Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cédrik, Schöne"'
Autor:
Cédrik Schöne, Benjamin Balluff, Axel Walch, Liam A. McDonnell, Michaela Aubele, Wilma E. Mesker, Emrys A. Jones, T.J.A. Dekker, Manfred Schmitt, Rob A. E. M. Tollenaar, Vincent T.H.B.M. Smit, Judith R. Kroep
Publikováno v:
J. Proteome Res. 13, 4730-4738 (2014)
Journal of Proteome Research, 13(11), 4730-4738
Journal of Proteome Research, 13(11), 4730-4738
MALDI mass spectrometry imaging (MSI) has rapidly established itself as a powerful biomarker discovery tool. To date, no formal investigation has assessed the center-to-center comparability of MALDI MSI experiments, an essential step for it to develo
Autor:
Marius Ueffing, Cédrik Schöne, Rupert Langer, Stefanie M. Hauck, Stefan Maier, Benjamin Balluff, Ludwig Hierber, Axel Walch, Stephan Meding, Marcus Feith, Michaela Aichler, Manfred Schmitt, Bernhard Kuster, Sandra Rauser, H. Braselmann, Horst Zitzelsberger, Heinz Höfler, Mareike Elsner, Michaela Aubele, Natalie Ludyga, Verena Zangen, Hans Zischka, Annette Feuchtinger
Publikováno v:
The Journal of Pathology. 230:410-419
Chemotherapeutic drugs kill cancer cells, but it is unclear why this happens in responding patients but not in non-responders. Proteomic profiles of patients with oesophageal adenocarcinoma may be helpful in predicting response and selecting more eff
Autor:
Hakan Sarioglu, Axel Walch, Sandra Rauser, Bernhard Kuster, Benjamin Balluff, Mareike Elsner, Gerhard Jung, Michaela Aichler, Cédrik Schöne, Heinz Höfler, Horst Zitzelsberger, Giuseppina Maccarrone, Stephan Meding, Marcus Feith, Uta Jütting, Stefan Maier, Marius Ueffing, Rupert Langer, Martin Nipp, Annette Feuchtinger
Publikováno v:
Journal of Proteomics. 75:4693-4704
To characterize proteomic changes found in Barrett's adenocarcinoma and its premalignant stages, the proteomic profiles of histologically defined precursor and invasive carcinoma lesions were analyzed by MALDI imaging MS. For a primary proteomic scre
Autor:
Stephan Meding, Helmut Friess, Heinz Höfler, Axel Walch, Stefanie M. Hauck, Marius Ueffing, Rupert Langer, Alexander Schäfer, Sandra Rauser, Robert D. Rosenberg, Cédrik Schöne, Mareike Elsner, Matthias Maak, Benjamin Balluff, Ulrich Nitsche
Publikováno v:
The Journal of Pathology. 228:459-470
Regional lymph node metastasis negatively affects prognosis in colon cancer patients. The molecular processes leading to regional lymph node metastasis are only partially understood and proteomic markers for metastasis are still scarce. Therefore, a
Autor:
Axel Walch, Benjamin Balluff, Robert D. Rosenberg, Rupert Langer, Helmut Friess, Cédrik Schöne, Matthias Maak, Heinz Höfler, Matthias P. Ebert, Stephan Meding, Marcus Feith, Ulrich Nitsche, Martin Nipp, Mareike Elsner, Sandra Rauser, Horst Zitzelsberger
Publikováno v:
Journal of Proteome Research. 11:1996-2003
In clinical diagnostics, it is of outmost importance to correctly identify the source of a metastatic tumor, especially if no apparent primary tumor is present. Tissue-based proteomics might allow correct tumor classification. As a result, we perform
Publikováno v:
Histochemistry and Cell Biology. 136:227-244
Matrix assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a method that allows the investigation of the molecular content of tissues within its morphological context. Since it is able to measure the distribution of hundre
Autor:
Stefanie M. Hauck, Michael Becker, Stephan Meding, Michaela Aichler, Detlev Suckau, Axel Walch, Janine Rattke, Marius Ueffing, Alice Ly, Cédrik Schöne
Publikováno v:
Histochemistry and cell biology. 143(5)
Matrix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI) is emerging as a powerful tool for the analysis of molecular distributions in biological samples in situ. When compared to classical histology, the major benefit of th
Autor:
Michaela, Aichler, Mareike, Elsner, Natalie, Ludyga, Annette, Feuchtinger, Verena, Zangen, Stefan K, Maier, Benjamin, Balluff, Cédrik, Schöne, Ludwig, Hierber, Herbert, Braselmann, Stephan, Meding, Sandra, Rauser, Hans, Zischka, Michaela, Aubele, Manfred, Schmitt, Marcus, Feith, Stefanie M, Hauck, Marius, Ueffing, Rupert, Langer, Bernhard, Kuster, Horst, Zitzelsberger, Heinz, Höfler, Axel K, Walch
Publikováno v:
The Journal of pathology. 230(4)
Chemotherapeutic drugs kill cancer cells, but it is unclear why this happens in responding patients but not in non-responders. Proteomic profiles of patients with oesophageal adenocarcinoma may be helpful in predicting response and selecting more eff
Publikováno v:
Clinical biochemistry. 46(6)
Despite the tendency to regard tumors as a simple mass of cancer cells, tumors have a high degree of complexity that is difficult to access with most analytical methods. Because the cancer tissue itself directly contains all information concerning pr
Autor:
Alexander Novotny, Hakan Sarioglu, Sandra Rauser, Benjamin Balluff, Marius Ueffing, Giuseppina Maccarrone, Heinz Höfler, Christoph Schuhmacher, Mareike Elsner, Horst Zitzelsberger, Stephan Meding, Annette Feuchtinger, H. Braselmann, Roland M. Schmid, Cédrik Schöne, Matthias P. Ebert, Axel Walch, Uta Jütting
Publikováno v:
Am. J. Pathol. 179, 2720-2729 (2011)
Proteomics-based approaches allow us to investigate the biology of cancer beyond genomic initiatives. We used histology-based matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry to identify proteins that predict disease outc