Výsledky vyhledávání - "Cédric Laloyaux"

Akademický článek

Change Blindness to Gradual Changes in Facial Expressions

Autor: Elodie David, Cédric Laloyaux, Christel Devue, Axel Cleeremans

Publikováno v: Psychologica Belgica, Vol 46, Iss 4, Pp 253-268 (2006)

Change blindness – our inability to detect changes in a stimulus – occurs even when the change takes place gradually, without disruption (Simons, Franconeri, & Reimer, 2000). Such gradual changes are more difficult to detect than changes that inv

Externí odkaz: https://doaj.org/article/dc3f5c2e77b1448aa6a6a2bfc80da6c8

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Tolerability and efficacy of adjunctive brivaracetam in adults with focal seizures by concomitant antiseizure medication use: Pooled results from three phase 3 trials

Autor: Philippe Ryvlin, Svetlana Dimova, Sami Elmoufti, Florin Floricel, Cédric Laloyaux, Xavier Nondonfaz, Victor Biton

Publikováno v: Ryvlin, P, Dimova, S, Elmoufti, S, Floricel, F, Laloyaux, C, Nondonfaz, X & Biton, V 2022, ' Tolerability and efficacy of adjunctive brivaracetam in adults with focal seizures by concomitant antiseizure medication use : Pooled results from three phase 3 trials ', Epilepsia, vol. 63, no. 8, pp. 2024-2036 . https://doi.org/10.1111/epi.17304

Objective: This study was undertaken to evaluate safety/tolerability and efficacy of adjunctive brivaracetam (BRV) in patients on one or two concomitant antiseizure medications (ASMs) and in patients on one specific concomitant ASM. Methods: Post hoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe708e073149db2d42b0072ca0a277ba
https://pubmed.ncbi.nlm.nih.gov/35582748

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Retention, efficacy, tolerability, and quality of life during long-term adjunctive brivaracetam treatment by number of lifetime antiseizure medications: A post hoc analysis of phase 3 trials in adults with focal seizures

Autor: Christian, Brandt, Svetlana, Dimova, Sami, Elmoufti, Cédric, Laloyaux, Xavier, Nondonfaz, Pavel, Klein

Publikováno v: Epilepsy & Behavior. 138:108967

To evaluate long-term retention, reasons for discontinuation, efficacy, tolerability, and health-related quality of life (HRQOL) during adjunctive brivaracetam (BRV) treatment in adults with focal seizures by number of lifetime antiseizure medication

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca98eca4f9abe613da693da58eb786db
https://doi.org/10.1016/j.yebeh.2022.108967

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Effect of Number of Previous Antiseizure Medications on Efficacy and Tolerability of Adjunctive Brivaracetam for Uncontrolled Focal Seizures: Post Hoc Analysis

Autor: Sang-Ahm Lee, Cédric Laloyaux, Boeun Hur, Sung Eun Kim, Sang-Kun Lee, Sami Elmoufti, Kyoung Heo

Publikováno v: Advances in therapy. 38(7)

The aim was to evaluate the efficacy and tolerability of adjunctive brivaracetam (BRV) in adults with severely drug-resistant focal seizures versus adults with less drug-resistant disease. Data were pooled from patients with focal seizures on 1–2 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ba397b0087eadf6e0f961d2c3473cc
https://pubmed.ncbi.nlm.nih.gov/34155568

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Behavioral adverse events with brivaracetam, levetiracetam, perampanel, and topiramate: A systematic review

Autor: Manuel Toledo, John M. Stern, Joseph I Sirven, Patricia A. Zipfel, Kristen Ricchetti-Masterson, Pavel Klein, Brien J. Smith, Brian D. Moseley, Henrik Klitgaard, Bernhard J. Steinhoff, Cédric Laloyaux, Vicente Villanueva, Felix Rosenow

Publikováno v: Epilepsybehavior : EB. 118

Purpose To understand the currently available post-marketing real-world evidence of the incidences of and discontinuations due to the BAEs of irritability, anger, and aggression in people with epilepsy (PWE) treated with the anti-seizure medications

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d334e8da5586923e8e2d6e0440a4ec
https://pubmed.ncbi.nlm.nih.gov/33839453

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Long-term safety and efficacy of brivaracetam in adults with focal seizures: Results from an open-label, multinational, follow-up trial

Autor: Stephen Yates, Anne-Liv Schulz, Sami Elmoufti, Cédric Laloyaux, Toufic Fakhoury, Stephan Arnold

Publikováno v: Epilepsy research. 166

Background This long-term follow-up (LTFU) trial was conducted to evaluate the long-term safety and tolerability of brivaracetam (BRV) at individualized doses (maximum of 200 mg/day) in patients with focal seizures. The secondary objective was to eva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe79aaa2140e585a163a16dad11b3d5
https://pubmed.ncbi.nlm.nih.gov/32731118

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Time course of drug-related treatment-emergent adverse side effects of brivaracetam

Autor: Cédric Laloyaux, Pavel Klein, Jesse Fishman, Kimford J. Meador, Sami Elmoufti, Teresa Gasalla, Melinda S. Martin

Publikováno v: Epilepsybehavior : EB. 111

Treatment-emergent adverse events (TEAEs) in clinical trials are typically reported for the full duration of the treatment period including titration and maintenance. Drug-related central nervous system (CNS) TEAEs are common with antiseizure medicat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0686a05d60b0499d01ebcb1c446447f2
https://pubmed.ncbi.nlm.nih.gov/32544700

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Time course of 75%-100% efficacy response of adjunctive brivaracetam

Autor: Cédric Laloyaux, Sami Elmoufti, Pavel Klein, Melinda S. Martin, Teresa Gasalla

Publikováno v: Acta Neurologica Scandinavica

BACKGROUND Time to sustained seizure frequency reduction can provide clinically meaningful epilepsy outcomes. AIMS OF THE STUDY To examine the time course of brivaracetam (BRV) efficacy in adults with focal seizures and focal to bilateral tonic-cloni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5e7b0a67daee06ac6845c551922690
https://pubmed.ncbi.nlm.nih.gov/32432339

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Long-term efficacy and tolerability of adjunctive brivaracetam in adults with focal to bilateral tonic-clonic (secondary generalized) seizures: Post hoc pooled analysis

Autor: Svetlana Dimova, Cédric Laloyaux, Aliakbar Asadi-Pooya, Brian D. Moseley, Sami Elmoufti

Publikováno v: Epilepsy Research. 176:106694

This post hoc analysis was conducted to evaluate the efficacy, tolerability, and health-related quality of life during long-term adjunctive brivaracetam (BRV) treatment in adult patients with focal to bilateral tonic-clonic seizures (FBTCS). Patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff82a9424aaf9a64e14a98ccec3d544
https://doi.org/10.1016/j.eplepsyres.2021.106694

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A review of the drug−drug interactions of the antiepileptic drug brivaracetam

Autor: Cédric Laloyaux, Brian D. Moseley, Jean-Marie Nicolas, Hugues Chanteux, Barry E. Gidal, Armel Stockis

Publikováno v: Epilepsy Research. 163:106327

Brivaracetam is an antiepileptic drug (AED) indicated for the treatment of focal seizures, with improved safety and tolerability vs first-generation AEDs. Brivaracetam binds with high affinity to synaptic vesicle protein 2A in the brain, which confer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2036ecc045a560595ec47d166a18c0e9
https://doi.org/10.1016/j.eplepsyres.2020.106327

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