Výsledky vyhledávání - "Cédric Godefroy"

TAT-RasGAP 317-326 kills cells by targeting inner-leaflet–enriched phospholipids

Autor: Christian Widmann, Filip Stojceski, Pierre-Emmanuel Milhiet, Gabriel Ichim, Gianvito Grasso, Robyn Roth, Cédric Godefroy, Kushal Kumar Das, Andrea Danani, Marc Serulla, Tim Schober, Ana J. García-Sáez, Sergii Afonin, Mathieu Heulot

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (50), pp.31871-31881. ⟨10.1073/pnas.2014108117⟩
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (50), pp.31871-31881. ⟨10.1073/pnas.2014108117⟩

International audience; TAT-RasGAP 317–326 is a cell-penetrating peptide-based construct with anticancer and antimicrobial activities. This peptide kills a subset of cancer cells in a manner that does not involve known programmed cell death pathway

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b26f0b4c3c018a1b1ed8e632f43982
https://doi.org/10.1073/pnas.2014108117

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Correlative AFM and fluorescence imaging demonstrate nanoscale membrane remodeling and ring-like and tubular structure formation by septins

Autor: Stéphanie Mangenot, Cyntia Taveneau, Hussein Nasrallah, Brieuc Chauvin, Daniel Lévy, Cédric Godefroy, Luca Costa, Patrice Dosset, Pierre-Emmanuel Milhiet, Aurélie Bertin, Anthony Vial, Kien Xuan Ngo, Hervé Isambert

Publikováno v: Nanoscale
Nanoscale, Royal Society of Chemistry, In press, ⟨10.1039/D1NR01978C⟩

International audience; Septins are ubiquitous cytoskeletal filaments that interact with the inner plasma membrane and are essential for cell division in eukaryotes. In cellular contexts, septins are often localized at micrometric Gaussian curvatures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ebd11428ea6e249f84d2dff27d8398
https://hal.sorbonne-universite.fr/hal-03280303

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Imaging Artificial Membranes Using High-Speed Atomic Force Microscopy

Autor: Hussein, Nasrallah, Anthony, Vial, Nicolas, Pocholle, Jérémy, Soulier, Luca, Costa, Cédric, Godefroy, Eric, Bourillot, Eric, Lesniewska, Pierre-Emmanuel, Milhiet

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1886

Supported lipid bilayers represent a very attractive way to mimic biological membranes, especially to investigate molecular mechanisms associated with the lateral segregation of membrane components. Observation of these model membranes with high-spee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::83c6e7bbca5710bd11c3a2f6feb48680
https://pubmed.ncbi.nlm.nih.gov/30374861

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Imaging Artificial Membranes Using High-Speed Atomic Force Microscopy

Autor: Jérémy Soulier, Luca Costa, Cédric Godefroy, Eric Bourillot, Pierre-Emmanuel Milhiet, Anthony Vial, Nicolas Pocholle, Eric Lesniewska, Hussein Nasrallah

Publikováno v: Methods in Molecular Biology ISBN: 9781493988938
Methods in Molecular Biology
Methods in Molecular Biology, Humana Press/Springer Imprint, 2019, pp.45-59. ⟨10.1007/978-1-4939-8894-5_3⟩
Methods in Molecular Biology, 2019, pp.45-59. ⟨10.1007/978-1-4939-8894-5_3⟩

International audience; Supported lipid bilayers represent a very attractive way to mimic biological membranes, especially to investigate molecular mechanisms associated with the lateral segregation of membrane components. Observation of these model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e623421ed86f03e51fd5411d26150ae
https://doi.org/10.1007/978-1-4939-8894-5_3

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Mimicking Influenza Virus Fusion Using Supported Lipid Bilayers

Autor: Frédéric Ronzon, Olivier Adam, Pierre-Emmanuel Milhiet, Selma Dahmane, Patrice Dosset, Marie-Claire Nicolaï, Cédric Godefroy

Publikováno v: Langmuir. 30:11394-11400

Influenza virus infection is a serious public health problem in the world, and understanding the molecular mechanisms involved in viral replication is crucial. In this paper, we used a minimalist approach based on a lipid bilayer supported on mica, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4c8c50478fed4db0a0557589a5e96c
https://doi.org/10.1021/la502591a

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Structure and DNA-binding properties of the Bacillus subtilis SpoIIIE DNA translocase revealed by single-molecule and electron microscopies

Autor: Antoine Le Gall, Diego I. Cattoni, Marcelo Nollmann, Joséphine Lai-Kee-Him, Patrick Bron, Pierre-Emmanuel Milhiet, Shreyasi Thakur, Cédric Godefroy

Publikováno v: Nucleic Acids Research

SpoIIIE/FtsK are a family of ring-shaped, membrane-anchored, ATP-fuelled motors required to segregate DNA across bacterial membranes. This process is directional and requires that SpoIIIE/FtsK recognize highly skewed octameric sequences (SRS/KOPS for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820a133094d685d6a45ee77c223546b0
https://doi.org/10.1093/nar/gkt1231

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Milk Sphingomyelin Domains in Biomimetic Membranes and the Role of Cholesterol: Morphology and Nanomechanical Properties Investigated Using AFM and Force Spectroscopy

Autor: Shan Zou, Pierre-Emmanuel Milhiet, Cédric Godefroy, Véronique Vié, Fanny Guyomarc'H, Maohui Chen, Christelle Lopez

Publikováno v: Langmuir
Langmuir, 2014, 30 (22), pp.6516-6524. ⟨10.1021/la501640y⟩
Langmuir, American Chemical Society, 2014, 30 (22), pp.6516-6524. ⟨10.1021/la501640y⟩

Milk sphingomyelin (MSM) and cholesterol segregate into domains in the outer bilayer membrane surrounding milk fat globules. To elucidate the morphology and mechanical properties of theses domains, supported lipid bilayers with controlled molar propo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6422d634047c8f3e8374790b8206ca0d
https://hal.science/hal-01209643

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Interaction of Antibiotics with Lipid Vesicles on Thin Film Porous Silicon Using Reflectance Interferometric Fourier Transform Spectroscopy

Autor: Cédric Godefroy, Frédérique Cunin, Pierre-Emmanuel Milhiet, Stephanie Pace, Taryn Guinan, Nicolas H. Voelcker, Nicole Lautredou

Publikováno v: Langmuir
Langmuir, American Chemical Society, 2013, 29 (32), pp.10279−10286. ⟨10.1021/la401804e⟩

International audience; The ability to observe interactions of drugs with cell membranes is an important area in pharmaceutical research. However, these processes are often difficult to understand due to the dynamic nature of cell membranes. Therefor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9611444bd282a4c8d8c259d744c2ad8d
https://hal.archives-ouvertes.fr/hal-00881098

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SpoIIIE mechanism of directional translocation involves target search coupled to sequence-dependent motor stimulation

Autor: Emmanuel Margeat, Osvaldo Chara, Marcelo Nollmann, Cédric Godefroy, Diego I. Cattoni, Pierre-Emmanuel Milhiet, Sonia Trigueros

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

SpoIIIE/FtsK are membrane‐anchored, ATP‐fuelled, directional motors responsible for chromosomal segregation in bacteria. Directionality in these motors is governed by interactions between specialized sequence‐recognition modules (SpoIIIE‐γ/F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b25284bb19a4f827760f199abb10b4
http://ora.ox.ac.uk/objects/uuid:e02c0f1b-a9f1-4820-b2a4-8abf72e5a60a

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