Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Cédric Brulé"'
Autor:
Nicolas Perzo, Richard Leduc, Cédric Brulé, Hélène Castel, Laurent Prézeau, Jane-Eileen Joubert, Xavier Sainsily
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2014, 28 (12), pp.5148--62. ⟨10.1096/fj.14-249771⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2014, 28 (12), pp.5148--62. ⟨10.1096/fj.14-249771⟩
International audience; Biased agonism by G-protein-coupled receptor ligands has opened up strategies for targeted physiological or therapeutic actions. We hypothesized that urotensin II (UII)-derived peptides displayed unexpected physiological effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6205655519d1f3863353abc9202ea9d
https://doi.org/10.1096/fj.14-249771
https://doi.org/10.1096/fj.14-249771
Autor:
Alain Brans, Georges Dive, Jacqueline Marchand-Brynaert, Bernard Joris, Cédric Brulé, Eric Sauvage, Jérôme Grugier
Publikováno v:
Asian Journal of Organic Chemistry. 2:654-661
Nitroveratrole esters (i.e. 4,5-dimethoxy-2-nitrobenzyl (NV) esters) of penicillin and cephalosporin derivatives have been prepared in the course of a program dedicated to photosensitive protein microarrays. Surprisingly, some molecules revealed to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50506c25632c672c7ade00bc20469e14
https://doi.org/10.1002/ajoc.201300108
https://doi.org/10.1002/ajoc.201300108
Publikováno v:
European Journal of Organic Chemistry. 2008:3700-3708
The isopropenyl derivatives of representative classes of polycyclic aromatic hydrocarbons (PAHs) having four and five fused-ring systems, namely pyrene, chrysene, benzo[c]phenanthrene (BcPh), dibenzo[a,c]anthracene (benzo[f]tetraphene) and perylene,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2263b525207fa6a3ac869ea02265157
https://doi.org/10.1002/ejoc.200800252
https://doi.org/10.1002/ejoc.200800252
Autor:
Sonia Gouault-Bironneau, Cédric Brulé, Charles Portella, Tiziano Nocentini, Jean-Philippe Bouillon
Publikováno v:
Journal of Fluorine Chemistry
Journal of Fluorine Chemistry, Elsevier, 2007, 128 (10), pp.1300-1305. ⟨10.1016/j.jfluchem.2007.07.014⟩
Journal of Fluorine Chemistry, Elsevier, 2007, 128 (10), pp.1300-1305. ⟨10.1016/j.jfluchem.2007.07.014⟩
Under fluoride activation, the vinyl fluorine of perfluoroketene dithioacetal may be substituted by silylated nucleophiles. Using silyl alkynes, a formal transition metal free sila-Sonogashira cross-coupling reaction occurred. The resulting enynes we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6af387467709424d25a2e25fe4c9de2
https://doi.org/10.1016/j.jfluchem.2007.07.014
https://doi.org/10.1016/j.jfluchem.2007.07.014
Publikováno v:
The Journal of Organic Chemistry. 72:3232-3241
A series of novel carbocations were generated by low-temperature protonation of substituted benzo[c]phenanthrenes, B[c]Phs, and their charge delocalization pathways were elucidated by NMR on the basis of the magnitude of Deltadelta13C values. It has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369f93fd5184d7dbeb9e71887fb0f24e
https://doi.org/10.1021/jo0625453
https://doi.org/10.1021/jo0625453
Publikováno v:
European Journal of Organic Chemistry. 2007:487-497
Persistent carbocations were generated from five A-ring mono- and di-substituted phenanthrenes [3-OMe; 4-OMe, 1,3-bis(OMe), 2,4-bis(OMe), and 1,3-bis(Me)]. In all cases protonation occurs in the A-ring, ortho/para relative to methoxy or methyl substi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efe8a66c6603d3635ec3ef1ebdc4a110
https://doi.org/10.1002/ejoc.200600780
https://doi.org/10.1002/ejoc.200600780
Autor:
Norbert Hoffmann, Cédric Brulé, Véronique Bulach, Sinisa Marinkovic, Elise Prost, Jean-Marc Nuzillard
Publikováno v:
The Journal of Organic Chemistry. 69:1646-1651
Acetalization of 5-hydroxyfuran-2[5H]-one with l-menthol yields (5R)- (1) and (5S)-5-l-menthyloxyfuran-2[5H]-one (2) in equal amounts. The diastereomer 1 crystallizes preferentially. For the first time, the isolation of pure diastereoisomer 2 is repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e9471bfb40c2a05d1c3c6a7a21681d
https://doi.org/10.1021/jo030292x
https://doi.org/10.1021/jo030292x
Autor:
Norbert Hoffmann, Cédric Brulé
Publikováno v:
Tetrahedron Letters. 43:69-72
Ketyl radicals were produced from ketones by photochemical electron transfer and subsequent proton transfer from tertiary amines. These radicals were stereoselectively added to (5 R )-5-(−)-menthyloxy-2[5 H ]-furanone 1 . Due to their low reactivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655b9ae590bffdd301a0a399491f1c4d
https://doi.org/10.1016/s0040-4039(01)02089-5
https://doi.org/10.1016/s0040-4039(01)02089-5
Autor:
Stéphane A. Laporte, Richard Leduc, Brandon Zimmerman, Cédric Brulé, Christine Lavoie, François Béliveau, Antoine Désilets
Publikováno v:
The Journal of biological chemistry. 286(33)
The type II transmembrane serine protease TMPRSS6 (also known as matriptase-2) controls iron homeostasis through its negative regulation of expression of hepcidin, a key hormone involved in iron metabolism. Upstream of the hepcidin-regulated signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffd1c1bda7a391316f9aeadb50942b7
https://pubmed.ncbi.nlm.nih.gov/21724843
https://pubmed.ncbi.nlm.nih.gov/21724843
Autor:
Cédric Brulé, Solo Goldstein, Jean A. Boutin, Isabelle Pevet, Arnaud Gohier, André Tizot, Francisco Cruzalegui
Publikováno v:
Bioorganicmedicinal chemistry. 19(8)
Among the recently investigated targets for cancer therapy is the c-Src non-receptor tyrosine kinase. Indeed research around deregulated activity of this enzyme has proven its role in tumor progression, while the beneficial effects of c-Src inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888f403fa78f7c59fd14881b6701ec31
https://pubmed.ncbi.nlm.nih.gov/21459579
https://pubmed.ncbi.nlm.nih.gov/21459579