The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression

Autor: Hélène Lazareth, Carole Henique, Olivia Lenoir, Victor G. Puelles, Martin Flamant, Guillaume Bollée, Cécile Fligny, Marine Camus, Lea Guyonnet, Corinne Millien, François Gaillard, Anna Chipont, Blaise Robin, Sylvie Fabrega, Neeraj Dhaun, Eric Camerer, Oliver Kretz, Florian Grahammer, Fabian Braun, Tobias B. Huber, Dominique Nochy, Chantal Mandet, Patrick Bruneval, Laurent Mesnard, Eric Thervet, Alexandre Karras, François Le Naour, Eric Rubinstein, Claude Boucheix, Antigoni Alexandrou, Marcus J. Moeller, Cédric Bouzigues, Pierre-Louis Tharaux

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)

In both focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN), kidney injury is characterised by the invasion of glomerular tufts by parietal epithelial cells (PECs). Here Lazareth et al. identify the tetraspanin CD9 as a

Externí odkaz: https://doaj.org/article/b682a5c3bcb44d6ba72e2b6a4e2372c3

Transient Directed Motions of GABAA Receptors in Growth Cones Detected by a Speed Correlation Index

Autor: Cédric Bouzigues, Maxime Dahan

Publikováno v: Biophysical Journal. 92:654-660

Single-molecule tracking of membrane proteins has become an important tool for investigating dynamic processes in live cells, such as cell signaling, membrane compartmentation or trafficking. The extraction of relevant parameters, such as interaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b20e9817a868a6d0d0ae2318c4d5063
https://doi.org/10.1529/biophysj.106.094524

Single europium-doped nanoparticles measure temporal pattern of reactive oxygen species production inside cells

Autor: Antigoni Alexandrou, Thanh-Liem Nguyen, Pierre-Louis Tharaux, Thierry Gacoin, Didier Casanova, Jean-Pierre Boilot, Latifa Bouzhir-Sima, Cédric Bouzigues, Rivo Ramodiharilafy

Publikováno v: Nature Nanotechnology
Nature Nanotechnology, Nature Publishing Group, 2009, 4 (9), pp.581. 〈10.1038/nnano.2009.200〉
Nature Nanotechnology, Nature Publishing Group, 2009, 4 (9), pp.581. ⟨10.1038/nnano.2009.200⟩

Low concentrations of reactive oxygen species, notably hydrogen peroxide (H2O2), mediate various signalling processes in the cell1,2. Production of these signals is highly regulated3 and a suitable probe is needed to measure these events. Here, we sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59b8d970716c941ae0b7de5ee063876
https://hal-polytechnique.archives-ouvertes.fr/hal-00818493

Asymmetric redistribution of GABA receptors during GABA gradient sensing by nerve growth cones analyzed by single quantum dot imaging

Autor: Mathieu Morel, Antoine Triller, Maxime Dahan, Cédric Bouzigues

During development of the nervous system, the tip of a growing axon, the growth cone (GC), must respond accurately to stimuli that direct its growth. This axonal navigation depends on extracellular concentration gradients of numerous guidance cues, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603ff06faa17e48ca23f130e85852c6b
https://europepmc.org/articles/PMC2040885/

Single Quantum Dot Tracking of Membrane Receptors

Autor: Cédric Bouzigues, Antoine Triller, Sabine Lévi, Maxime Dahan

The dynamics of membrane proteins in living cells has become a major issue to understand important biological questions such as chemotaxis, synaptic regulation, or signal transduction. The advent of semi-conductor quantum dots (QDs) has opened new pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3430c1c309d6221db861c3eb4fd3ff8d
https://doi.org/10.1385/1-59745-369-2:81