Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cédric Barrière"'
Autor:
Hélène Bonnevaux, Stephane Guerif, Jana Albrecht, Erwan Jouannot, Thibaud De Gallier, Christian Beil, Christian Lange, Wulf Dirk Leuschner, Marion Schneider, Cendrine Lemoine, Anne Caron, Céline Amara, Cédric Barrière, Justine Siavellis, Valérie Bardet, Ernesto Luna, Pankaj Agrawal, Donald R. Drake, Ercole Rao, Peter Wonerow, Chantal Carrez, Véronique Blanc, Karl Hsu, Dmitri Wiederschain, Paula G. Fraenkel, Angéla Virone-Oddos
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Novel therapies are needed for effective treatment of AML. In the relapsed setting, prognosis is very poor despite salvage treatment with chemotherapy. Evidence suggests that leukemic stem cells (LSCs) cause relapse. The cell surface receptor CD123 i
Externí odkaz:
https://doaj.org/article/1e989dd4f1bc4fabbee1419fc76e4439
Autor:
Laurent Debussche, Dimitri Gorge-Bernat, Pascal Pannier, Stéphane Guerif, Laurent Besret, Odette Dos-Santos, Angelo Aguilar, Denzil Bernard, Shanghai Yu, Sanjeev Shangary, Jianfeng Lu, Cassandra Gianna Hoffman-Luca, Liu Liu, Longchuan Bai, Jennifer L. Meagher, Jeanne A. Stuckey, Cédric Barrière, Isabelle Meaux, Donna McEachern, Yujun Zhao, Wei Sun, Shaomeng Wang
SI Table S1. Crystallography data collection and refinement statistics for the co-crystal structure of SAR405838 complexed with human MMD2 protein. SI Table S2. Binding affinities of SAR405838, as well as reference compounds to different MDM2 protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10ee835201ab25b1bcd7983435e9cfe
https://doi.org/10.1158/0008-5472.22403966
https://doi.org/10.1158/0008-5472.22403966
Autor:
Benoit Pasquier, Youssef El-Ahmad, Bruno Filoche-Rommé, Christine Dureuil, Florence Fassy, Pierre-Yves Abecassis, Magali Mathieu, Thomas Bertrand, Tsiala Benard, Cédric Barrière, Samira El Batti, Jean-Philippe Letallec, Véronique Sonnefraud, Maurice Brollo, Laurence Delbarre, Véronique Loyau, Fabienne Pilorge, Luc Bertin, Patrick Richepin, Jérôme Arigon, Jean-Robert Labrosse, Jacques Clément, Florence Durand, Romain Combet, Pierre Perraut, Vincent Leroy, Frédéric Gay, Dominique Lefrançois, François Bretin, Jean-Pierre Marquette, Nadine Michot, Anne Caron, Christelle Castell, Laurent Schio, Gary McCort, Hélène Goulaouic, Carlos Garcia-Echeverria, Baptiste Ronan
Publikováno v:
Journal of Medicinal Chemistry. 58:376-400
Vps34 (the human class III phosphoinositide 3-kinase) is a lipid kinase involved in vesicle trafficking and autophagy and therefore constitutes an interesting target for cancer treatment. Because of the lack of specific Vps34 kinase inhibitors, we ai
Autor:
Claudine Tardy, Kathryn Newton, Marcos Malumbres, Antonio Cerqueira, Javier F. Cáceres, David Santamaría, Cédric Barrière, Mariano Barbacid, Pierre Dubus, Sarah L. Hunt
Publikováno v:
Nature. 448:811-815
Unicellular organisms such as yeasts require a single cyclin-dependent kinase, Cdk1, to drive cell division. In contrast, mammalian cells are thought to require the sequential activation of at least four different cyclin-dependent kinases, Cdk2, Cdk3
Autor:
Elodie Girard, Emmanuel Barillot, Perrine Paul-Gilloteaux, Silvia Fre, Silvina Dos Reis Tavares, David P. A. Cohen, Maia Chanrion, Andrei Zinovyev, Luc Fetler, Lev Stimmer, Ivan Bièche, Patricia Legoix-Né, Cédric Barrière, Danijela Matic Vignjevic, Sylvie Robine, Inna Kuperstein, Loredana Martignetti, Daniel Louvard, Giuseppe-Fulvio Boccia, Didier Meseure, Fatima El Marjou, Wulfran Cacheux
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2014, 5, pp.5005. ⟨10.1038/ncomms6005⟩
Nature Communications, 2014, 5, pp.5005. ⟨10.1038/ncomms6005⟩
Nature Communications, Nature Publishing Group, 2014, 5, pp.5005. ⟨10.1038/ncomms6005⟩
Nature Communications, 2014, 5, pp.5005. ⟨10.1038/ncomms6005⟩
Epithelial-to-mesenchymal transition-like (EMT-like) is a critical process allowing initiation of metastases during tumour progression. Here, to investigate its role in intestinal cancer, we combine computational network-based and experimental approa
Autor:
David Santamaría, Javier Galán, Sagrario Ortega, Antonio Cerqueira, Cédric Barrière, Pierre Dubus, Mariano Barbacid, Alberto Martín, Marcos Malumbres
Publikováno v:
Molecular oncology. 1(1)
Mammalian cell division is thought to be driven by sequential activation of several Cyclin-dependent kinases (Cdk), mainly Cdk4, Cdk6, Cdk2 and Cdk1. Since mice lacking Cdk4, Cdk6 or Cdk2 are viable, it has been proposed that they play compensatory r