Výsledky vyhledávání - "Cécile Thomas de La Pintière"

Vγ9Vδ2 T cell-mediated recognition of human solid tumors. Potential for immunotherapy of hepatocellular and colorectal carcinomas

Autor: Pascale Daniel, Karim Boudjema, Françoise Bouet-Toussaint, Florian Cabillic, Eric Dupont-Bierre, Olivier Toutirais, Véronique Catros, Cécile Thomas de La Pintière, Bernard Meunier, Noëlle Genetet, Matthieu Le Gallo

Publikováno v: Cancer Immunology, Immunotherapy. 57:531-539

Vgamma9Vdelta2 T lymphocytes are reported to participate in the anti-tumor immune surveillance in human. They are known to recognize phosphoantigens and molecules expressed on cells undergoing neoplasic transformation. In this study, we investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da67f1d0dd5d2fe6a86b0d7ebbb04fa
https://doi.org/10.1007/s00262-007-0391-3

Zobrazit plný text záznamu

CRTAM receptor engagement by Necl-2 on tumor cells triggers cell death of activated Vγ9Vδ2 T cells

Autor: Benoit Dessarthe, Pascale Daniel, Florian Cabillic, Aurélie Drouet, Véronique Catros, Aurélie Thedrez, Cécile Thomas de La Pintière, Jean-Baptiste Latouche, Olivier Toutirais

Publikováno v: Journal of Immunology
Journal of Immunology, 2013, 190 (9), pp.4868-76. ⟨10.4049/jimmunol.1202596⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2013, 190 (9), pp.4868-76. ⟨10.4049/jimmunol.1202596⟩

Human Vγ9Vδ2 T cells exert potent in vitro and in vivo antitumor activities, making them promising candidates for immunotherapy strategies. Recognition of tumor cells by Vγ9Vδ2 T cells requires engagement of the TCR and/or NK receptors. Recently,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dce91a23326cd586579b4887e57f15
https://pubmed.ncbi.nlm.nih.gov/23530148

Zobrazit plný text záznamu

New types of primers (stair primers) for PCR amplification of the variable V3 region of the human immunodeficiency virus

Autor: Annick Ruffault, Sophie Minjolle, François Cartier, Christian Michelet, Cécile Thomas De La Pintière, Ronald Colimon, Patrice Andre

Publikováno v: Journal of Virological Methods. 58:7-19

The aim of the study was to develop a reliable PCR method for the detection of viral genomes with frequent mutations like HIV and hepatitis C virus. A system of 'stair' primers is suggested which allows amplification of a genomic sequence despite the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f6361d39835fdb3d86111b86a146b7
https://doi.org/10.1016/0166-0934(95)01967-7

Zobrazit plný text záznamu

Sensitization of ovarian carcinoma cells with zoledronate restores the cytotoxic capacity of Vγ9Vδ2 T cells impaired by the prostaglandin E2 immunosuppressive factor: implications for immunotherapy

Autor: Sébastien Henno, Jean Levêque, Benoit Dessarthe, Vincent Lavoué, Estelle Bauville, F. Foucher, Pascale Daniel, Olivier Toutirais, Jean-Yves Bansard, Françoise Bouet-Toussaint, Florian Cabillic, Aurélie Thedrez, Cécile Thomas de La Pintière, Véronique Catros, Florence Burtin

Publikováno v: International Journal of Cancer
International Journal of Cancer, Wiley, 2012, 131 (4), pp.E449-62. ⟨10.1002/ijc.27353⟩
International Journal of Cancer, 2012, 131 (4), pp.E449-62. ⟨10.1002/ijc.27353⟩

International audience; Epithelial ovarian cancer (EOC) usually spreads into the peritoneal cavity, thereby providing an opportunity for intraperitoneal adoptive immunotherapy with Vγ9Vδ2 T lymphocytes, a T cell subpopulation endowed with high lyti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0a6e4d4194d409df54afa37b153e7e
https://hal.archives-ouvertes.fr/hal-00739882

Zobrazit plný text záznamu

HLA-A*0201-restricted CEA-derived peptide CAP1 is not a suitable target for T-cell-based immunotherapy

Autor: Aurélie Drouet, Jean Baptiste Latouche, Thierry Frebourg, Emilie Fauquembergue, Jérôme Leprince, Mireille Desille, Florian Cabillic, Véronique Catros, Hubert Vaudry, Olivier Toutirais, Licia Rivoltini, Cécile Thomas de La Pintière, Stéphanie Baert-Desurmont, Richard Sesboüé, David Tougeron, Matthieu Le Gallo, Manuela Iero

Publikováno v: Journal of immunotherapy : official journal of the Society for Biological Therapy
Journal of immunotherapy : official journal of the Society for Biological Therapy, Raven Press Publishers, 2010, 33 (4), pp.402-13. ⟨10.1097/CJI.0b013e3181d366da⟩
Journal of immunotherapy : official journal of the Society for Biological Therapy, 2010, 33 (4), pp.402-13. ⟨10.1097/CJI.0b013e3181d366da⟩
Scopus-Elsevier

International audience; Carcinoembryonic antigen (CEA) is a potential target for antigen-specific immunotherapy, as it is frequently overexpressed in human carcinomas. Moreover, an epitope derived from CEA, designated CAP1 (YLSGANLNL), has been propo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c52555f89d3082ba8ce4cb055582cc
https://hal.archives-ouvertes.fr/hal-00742157

Zobrazit plný text záznamu

Aminobisphosphonate-pretreated dendritic cells trigger successful Vgamma9Vdelta2 T cell amplification for immunotherapy in advanced cancer patients

Autor: Florian Cabillic, Cécile Thomas de La Pintière, Pascale Daniel, Véronique Catros, Bruno Turlin, Karim Boudjema, Hannu Mönkkönen, Olivier Toutirais, Jukka Mönkkönen, Vincent Lavoué, Nathalie Rioux-Leclerc, Françoise Bouet-Toussaint

Publikováno v: Cancer Immunology, Immunotherapy
Cancer Immunology, Immunotherapy, 2010, 59 (11), pp.1611-9. ⟨10.1007/s00262-010-0887-0⟩
Cancer Immunology, Immunotherapy, Springer Verlag, 2010, 59 (11), pp.1611-9. ⟨10.1007/s00262-010-0887-0⟩

International audience; Hepatocellular carcinoma (HCC) and colorectal carcinoma with hepatic metastases (mCRC) are cancers with poor prognosis and limited therapeutic options. New approaches are needed and adoptive immunotherapy with Vgamma9Vdelta2 T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f1d1203bb9cf8b3c9fa85e4d32376d
https://pubmed.ncbi.nlm.nih.gov/20582413

Zobrazit plný text záznamu

DNAX accessory molecule-1 (CD226) promotes human hepatocellular carcinoma cell lysis by Vgamma9Vdelta2 T cells

Autor: Cécile Thomas de La Pintière, Olivier Toutirais, Samuel Salot, Pascale Daniel, Mireille Desille, Pascal Loyer, Gaelle Le Friec, Françoise Bouet, Véronique Catros, Matthieu Le Gallo, Florian Cabillic

Publikováno v: European journal of immunology. 39(5)

Human Vgamma9Vdelta2 T lymphocytes can be activated by nonpeptidic antigens such as the mevalonate pathway-derived isopentenyl pyrophosphate or synthetic phosphoantigen such as bromohydrin pyrophosphate. They display a strong cytotoxic activity again

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fddfb4018204f5ab32cad8604d7b4e48
https://pubmed.ncbi.nlm.nih.gov/19404979

Zobrazit plný text záznamu

Cytotoxic effector cells with antitumor activity can be amplified ex vivo from biopsies or blood of patients with renal cell carcinoma for cell therapy use

Autor: Nathalie Rioux-Leclercq, Noëlle Genetet, Françoise Bouet-Toussaint, Anne-Sophie Thirouard, Alban Gervais, Véronique Catros-Quemener, Jean-Jacques Patard, Cécile Thomas de La Pintière, M.-P. Ramee, Olivier Toutirais

Publikováno v: Cancer immunology, immunotherapy : CII. 52(11)

Adoptive immunotherapy with antitumor effector cells is an attractive therapeutic approach in metastatic renal cell carcinoma (RCC). The aim of the work was to enhance in vitro activation of lymphocytes with optimal cytotoxic activity against tumor c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa145404ef5e68482be296dc2bd91105
https://pubmed.ncbi.nlm.nih.gov/12879292

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání