Výsledky vyhledávání - "Cécile Taflin"

Akademický článek

Endothelial Cell Amplification of Regulatory T Cells Is Differentially Modified by Immunosuppressors and Intravenous Immunoglobulin

Autor: Julien Lion, Maren Burbach, Amy Cross, Karine Poussin, Cécile Taflin, Srini Kaveri, Alain Haziot, Denis Glotz, Nuala Mooney

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

Immunosuppressive treatment is a prerequisite for both organ transplantation and tolerance of the allograft. However, long-term immunosuppression has been associated with a higher incidence of malignancies and infections. Immunosuppressors mainly tar

Externí odkaz: https://doaj.org/article/2aff0f899d234c85b5e57d36bc11771a

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HLA Class II Antibody Activation of Endothelial Cells Promotes Th17 and Disrupts Regulatory T Lymphocyte Expansion

Autor: E. Mariotto, A. Savenay, Macarena Robledo-Sarmiento, Dominique Charron, Caroline Suberbielle, Nuala Mooney, Amy Cross, Denis Glotz, Cécile Taflin, Julien Lion, Alain Haziot, Maryvonnick Carmagnat

Publikováno v: American Journal of Transplantation
American Journal of Transplantation, 2016, 16 (5), pp.1408-1420. ⟨10.1111/ajt.13644⟩
American Journal of Transplantation, Wiley, 2016, 16 (5), pp.1408-1420. ⟨10.1111/ajt.13644⟩
Europe PubMed Central

Kidney transplantation is the most successful treatment option for patients with end-stage renal disease, and chronic antibody-mediated rejection is the principal cause of allograft loss. Predictive factors for chronic rejection include high levels o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4690d5f37668efd5e128fed27976daec
https://hal.science/hal-02325476

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Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

Autor: Masahiro Ono, Alexis Mathian, Zahir Amoura, Cécile Taflin, Yumiko Yoshioka, Kajsa Wing, Shimon Sakaguchi, Toshio Heike, Christophe Parizot, Dominique Valeyre, Makoto Miyara, Tomoyuki Yamaguchi, Akihiko Kitoh, Tomoko Shima, Takashi Nomura, Akira Niwa, Tatsutoshi Nakahata, Guy Gorochov

Publikováno v: Immunity. 30:899-911

FoxP3 is a key transcription factor for the development and function of natural CD4(+) regulatory T cells (Treg cells). Here we show that human FoxP3(+)CD4(+) T cells were composed of three phenotypically and functionally distinct subpopulations: CD4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0049d0c427f809eeafa8be79bc70056
https://doi.org/10.1016/j.immuni.2009.03.019

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FoxP3+ Regulatory T Cells Suppress Early Stages of Granuloma Formation but Have Little Impact on Sarcoidosis Lesions

Autor: Pascale Salek-Peyron, Makoto Miyara, Jean-Marc Naccache, Julien Haroche, Dominique Valeyre, Patrick Bruneval, Dominique Nochy, Cécile Taflin, Gary S. Hill, Alexis Mathian, Cécile Badoual, Guy Gorochov, Frédéric Altare, Zahir Amoura

Publikováno v: The American Journal of Pathology. 174:497-508

Sarcoidosis is characterized by a disproportionate Th1 granulomatous immune response in involved organs. It is also associated with both peripheral and intratissular regulatory T cell (Treg) expansion. These cells exhibit powerful antiproliferative a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc11552b5f1a4e708ffe4d4a433a920
https://doi.org/10.2353/ajpath.2009.080580

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Study of the allogeneic response induced by endothelial cells expressing HLA class II after lentiviral transduction

Autor: Cécile, Taflin, Benoit, Favier, Dominique, Charron, Denis, Glotz, Nuala, Mooney

Publikováno v: Methods in molecular biology (Clifton, N.J.). 960

Rejection is still the major cause of allograft loss following organ transplantation and a more complete comprehension of the alloimmune response is required in order to develop new therapeutic approaches. Allogenicity is primarily generated by the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96feb8e8947788e6b5124b71fd6cdabe
https://pubmed.ncbi.nlm.nih.gov/23329507

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Regulation of the CD4+ T cell allo-immune response by endothelial cells

Autor: Cécile Taflin, Dominique Charron, Nuala Mooney, Denis Glotz

Publikováno v: Human Immunology
Human Immunology, Elsevier, 2012, 73 (12), pp.1269-1274. ⟨10.1016/j.humimm.2012.07.009⟩

Recent studies have revealed the presence of pro-inflammatory and/or regulatory CD4(+) T cells within allografts promoting either graft rejection or tolerance. Histological evidence has identified the microvascular endothelium as the primary site of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e097fe50c141038895e5730a2e583d4
https://hal.archives-ouvertes.fr/hal-02325532

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Study of the Allogeneic Response Induced by Endothelial Cells Expressing HLA Class II After Lentiviral Transduction

Autor: Dominique Charron, Cécile Taflin, Denis Glotz, Benoit Favier, Nuala Mooney

Publikováno v: Antigen Processing ISBN: 9781627032179

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::057d537876aa870dacb98db03f053a88
https://doi.org/10.1007/978-1-62703-218-6_34

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Human endothelial cells generate Th17 and regulatory T cells under inflammatory conditions

Autor: Denis Glotz, Benoit Favier, Patrice Hemon, Armand Bensussan, Nuala Mooney, Dominique Charron, Jeremy Baudhuin, Alain Savenay, Cécile Taflin

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2011, 108 (7), pp.2891-2896. ⟨10.1073/pnas.1011811108⟩
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (7), pp.2891-2896. ⟨10.1073/pnas.1011811108⟩

Organ transplantation represents a unique therapeutic option for irreparable organ dysfunction and rejection of transplants results from a breakdown in operational tolerance. Although endothelial cells (ECs) are the first target in graft rejection fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b47a666eab6d1a690fdeb0b72a67d7
https://hal.archives-ouvertes.fr/hal-02325548

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Immunological function of the endothelial cell within the setting of organ transplantation

Autor: Denis Glotz, Cécile Taflin, Nuala Mooney, Dominique Charron

Publikováno v: Immunology letters. 139(1-2)

In organ transplantation, development of immunosuppressive treatment and improved diagnosis of allograft rejection has resulted in increased allograft survival in recent years. Nevertheless, rejection remains a major cause of graft loss and a better

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e054f39203e69add855d21018535b4a5
https://pubmed.ncbi.nlm.nih.gov/21641935

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