Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cécile Mingard"'
Autor:
Yang Jiang, Cécile Mingard, Sabrina M. Huber, Vakil Takhaveev, Maureen McKeague, Seiichiro Kizaki, Mirjam Schneider, Nathalie Ziegler, Vera Hürlimann, Julia Hoeng, Nicolas Sierro, Nikolai V. Ivanov, Shana J. Sturla
Publikováno v:
ACS Central Science, Vol 10, Iss 2, Pp 487-487 (2024)
Externí odkaz:
https://doaj.org/article/1d492b4c72f641b9b4fed67367b8adcb
Autor:
Cécile Mingard, James N. D. Battey, Vakil Takhaveev, Katharina Blatter, Vera Hürlimann, Nicolas Sierro, Nikolai V. Ivanov, Shana J. Sturla
Publikováno v:
Chemical Research in Toxicology, 36 (4)
Tobacco smoke delivers a complex mixture of hazardous and potentially hazardous chemicals. Some of these may induce the formation of DNA mutations, which increases the risk of various cancers that display characteristic patterns of accumulated mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a184fc51ff066698944979b5af107e
Autor:
Yang Jiang, Cécile Mingard, Sabrina M. Huber, Vakil Takhaveev, Maureen McKeague, Seiichiro Kizaki, Mirjam Schneider, Nathalie Ziegler, Vera Hürlimann, Julia Hoeng, Nicolas Sierro, Nikolai V. Ivanov, Shana J. Sturla
Publikováno v:
ACS Central Science, 9 (3)
Chemical modifications to DNA bases, including DNA adducts arising from reactions with electrophilic chemicals, are well-known to impact cell growth, miscode during replication, and influence disease etiology. However, knowledge of how genomic sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5c945859089740f0c7f9bcedc5db96
Publikováno v:
Chemical Society Reviews, 49 (20)
Cellular DNA is constantly chemically altered by exogenous and endogenous agents. As all processes of life depend on the transmission of the genetic information, multiple biological processes exist to ensure genome integrity. Chemically damaged DNA h
Autor:
Franziska Paech, Stephan Krähenbühl, Cécile Mingard, Vanessa F. Abegg, Jamal Bouitbir, David Grünig
Publikováno v:
Toxicology. 395
Previous studies have shown that certain kinase inhibitors are mitochondrial toxicants. In the current investigation, we determined the mechanisms of mitochondrial impairment by the kinase inhibitors ponatinib, regorafenib, and sorafenib in more deta
Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines
Publikováno v:
Journal of applied toxicology : JAT. 38(3)
Tyrosine kinase inhibitors have revolutionized the treatment of certain cancers. They are usually well tolerated, but can cause adverse reactions including liver injury. Currently, mechanisms of hepatotoxicity associated with tyrosine kinase inhibito