Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Cécile De Bruyn"'
Autor:
Basile Stamatopoulos, Nathalie Meuleman, Cécile De Bruyn, Karlien Pieters, Géraldine Anthoine, Philippe Mineur, Dominique Bron, Laurence Lagneaux
Publikováno v:
PLoS ONE, Vol 5, Iss 9, Pp 3307-3314 (2010)
BACKGROUND: Several markers have been proposed to predict the outcome of chronic lymphocytic leukemia (CLL) patients. However, discordances exist between the current prognostic factors, indicating that none of these factors are totally perfect. METHO
Externí odkaz:
https://doaj.org/article/f699ef4ed5c343d9816d21644a249b4c
Autor:
Thibaud André, Nathalie Meuleman, Basile Stamatopoulos, Cécile De Bruyn, Karlien Pieters, Dominique Bron, Laurence Lagneaux
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59756 (2013)
BACKGROUND: In multiple myeloma, bone marrow mesenchymal stromal cells support myeloma cell growth. Previous studies have suggested that direct and indirect interactions between malignant cells and bone marrow mesenchymal stromal cells result in cons
Externí odkaz:
https://doaj.org/article/33706c75bd60426aaccb649634f2ccde
Autor:
Basile Stamatopoulos, Nathalie Meuleman, Cécile De Bruyn, Karlien Pieters, Philippe Mineur, Christine Le Roy, Stéphane Saint-Georges, Nadine Varin-Blank, Florence Cymbalista, Dominique Bron, Laurence Lagneaux
Publikováno v:
Haematologica, Vol 97, Iss 4 (2012)
Background Interactions with the microenvironment, such as bone marrow mesenchymal stromal cells and nurse-like cells, protect chronic lymphocytic leukemia cells from spontaneous and drug-induced apoptosis. This protection is partially mediated by th
Externí odkaz:
https://doaj.org/article/e90b65b96e1a41afa3fe0fc80b30ead6
Autor:
Basile Stamatopoulos, Nathalie Meuleman, Cécile De Bruyn, Alain Delforge, Dominique Bron, Laurence Lagneaux
Publikováno v:
Haematologica, Vol 95, Iss 7 (2010)
Background Chronic lymphocytic leukemia is a neoplastic disorder that arises largely as a result of defective apoptosis leading to chemoresistance. Stromal cell-derived factor-1 and its receptor, CXCR4, have been shown to play an important role in ch
Externí odkaz:
https://doaj.org/article/d5955fdf238248eea1e7069f1a69a6ac
Autor:
Basile Stamatopoulos, Benjamin Haibe-Kains, Carole Equeter, Nathalie Meuleman, Anne Sorée, Cécile De Bruyn, Delphine Hanosset, Dominique Bron, Philippe Martiat, Laurence Lagneaux
Publikováno v:
Haematologica, Vol 94, Iss 6 (2009)
Background Zeta-associated protein 70 (ZAP70) is a widely recognized prognostic factor in chronic lymphocytic leukemia, but mechanisms by which its higher expression leads to a poor outcome must still be fully explained.Design and Methods In an attem
Externí odkaz:
https://doaj.org/article/b2a89117338443b39d80bf7455697dbf
Autor:
Laurence Lagneaux, Cécile De Bruyn, Dominique Bron, Hussein Fayyad-Kazan, Michel Toungouz, Gordana Raicevic, Mehdi Najar
Publikováno v:
Stem Cell Reviews and Reports. 11:442-452
Bone marrow mesenchymal stromal cells (BM-MSCs) display immunomodulatory features, representing a promising tool for cell-based therapies. However, the mechanisms used by MSCs to regulate T cell fate remain unclear.We investigated the potential of BM
Autor:
Mehdi, Najar, Gordana, Raicevic, Hussein, Fayyad-Kazan, Hussein Fayyad, Kazan, Cécile, De Bruyn, Dominique, Bron, Michel, Toungouz, Laurence, Lagneaux
Publikováno v:
Stem Cell Reviews and Reports. 8:1188-1198
Based on their ability to regulate immune responses, MSCs are considered to be potential candidates for managing immune-mediated diseases in the context of immune therapy. AT and WJ are considered valuable alternatives for BM as a source of MSCs. A d
Autor:
Laurence Lagneaux, Michel Toungouz, Gordana Raicevic, Dominique Bron, Mehdi Najar, Karlien Pieters, Cécile De Bruyn, Nathalie Meuleman
Publikováno v:
Tissue Engineering Part A. 18:1410-1418
Mesenchymal stromal cells (MSCs) can be isolated not only from bone marrow (BM) but also from other tissues, including adipose tissue (AT) and umbilical cord Wharton's Jelly (WJ). Thanks to their ability to differentiate into various cell types, MSC
Autor:
Mehdi Najar, Gordana Raicevic, Basile Stamatopoulos, Alain Delforge, Cécile De Bruyn, Laurence Lagneaux, Karlien Pieters, Nathalie Meuleman, Dominique Bron
Publikováno v:
Stem Cells and Development. 20:547-557
The co-infusion of mesenchymal stromal cells (MSCs) with hematopoietic stem cells could improve the hematopoietic engraftment after cord blood transplant. Adult bone marrow is the major source of MSCs for cell therapy. However, bone marrow aspiration
Autor:
Michel Toungouz, Laurence Lagneaux, Gordana Raicevic, Basile Stamatopoulos, Nathalie Meuleman, Mehdi Najar, Dominique Bron, Cécile De Bruyn, Hicham Id Boufker
Publikováno v:
Experimental Hematology. 38:922-932
Objective As mesenchymal stromal cells (MSCs) have been proposed as a tool for management or prevention of graft-vs-host disease, we investigated their immunoregulatory properties, their expression of adhesion molecules and galectin-1, and the impact