Výsledky vyhledávání - "Cécile Daussy"

Styk1 expression is a hallmark of murine NK cells and other NK1.1(+) subsets but is dispensable for NK cell development and effector functions

Autor: Sébastien Fauteux-Daniel, Cécile Daussy, Marie Marotel, Joseph C. Sun, Clair D. Geary, Thierry Walzer, Fabrice Faure

Publikováno v: Eur J Immunol

To gain insight into the biology of Natural Killer (NK) cells, others and we previously identified the NK cell signature, defined as the set of transcripts which expression is highly enriched in these cells compared to other immune subtypes. The tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4387a1257b1ee70cb7ac4fef6b584bdc
https://europepmc.org/articles/PMC8351758/

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S1PR5 is pivotal for the homeostasis of patrolling monocytes

Autor: Dominique Kaiserlian, Vincent Biajoux, Katia Mayol, Cécile Daussy, Morgan Taillardet, Thierry Walzer, Thomas Henry, Emilie Debien, Bertrand Dubois, Nicolas Dagany, Mercedes Gomez de Agüero, Karl Balabanian, Lilia Brinza, Jacqueline Marvel

Publikováno v: European Journal of Immunology. 43:1667-1675

Patrolling Ly6C(-) monocytes are blood-circulating cells that play a role in inflammation and in the defense against pathogens. Here, we show that similar to natural killer (NK) cells, patrolling monocytes express high levels of S1PR5, a G-coupled re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9bccac4f4cb045a947ff13108efadc5
https://doi.org/10.1002/eji.201343312

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Autoimmune lymphoproliferative syndrome caused by a homozygous null FAS ligand (FASLG) mutation

Autor: Marie-Claude Stolzenberg, Meghana Rao, Mukesh Desai, Manisha Madkaikar, Aude Magerus-Chatinet, Kanjaksha Ghosh, Cécile Daussy, Bénédicte Neven, Alain Fischer, Frédéric Rieux-Laucat, Nina Lanzarotti, Capucine Picard, Nathalie Neveux

Publikováno v: Journal of Allergy and Clinical Immunology. 131:486-490

Background Autoimmune lymphoproliferative syndrome (ALPS) is characterized by chronic nonmalignant lymphoproliferation, accumulation of double-negative T cells, hypergammaglobulinemia G and A, and autoimmune cytopenia. Objectives Although mostly asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1d277fc2cc8b3676771e85f4e878d6
https://doi.org/10.1016/j.jaci.2012.06.011

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Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation

Autor: Cécile Daussy, Gérard Michel, Aude Magerus-Chatinet, Filomeen Haerynck, Sophie Cluet-Dennetiere, Capucine Picard, Serge Romana, Alain Fischer, Nina Lanzarotti, Frédéric Rieux-Laucat, Christine Bole-Feysot, Catherine Schaffner, Mohammed Zarhrate, Isabelle Radford-Weiss, Marie-Claude Stolzenberg, Bénédicte Neven, Peter D. Arkwright

Publikováno v: JOURNAL OF CLINICAL INVESTIGATION

Autoimmune diseases develop in approximately 5% of humans. They can arise when self-tolerance checkpoints of the immune system are bypassed as a consequence of inherited mutations of key genes involved in lymphocyte activation, survival, or death. Fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14155564f229abc388c10ec3a154ec0f
https://doi.org/10.1172/jci43752

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Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

Publikováno v: The Journal of Experimental Medicine
JOURNAL OF EXPERIMENTAL MEDICINE
Journal of Experimental Medicine
Journal of Experimental Medicine, 2015, 212 (12), pp.2015-2025. ⟨10.1084/jem.20150809⟩
Journal of Experimental Medicine, 212(12), 2015-2025. Rockefeller University Press
Journal of Experimental Medicine, Rockefeller University Press, 2015, 212 (12), pp.2015-2025. ⟨10.1084/jem.20150809⟩

The transcription factor Zeb2 cooperates with T-bet to control NK cell maturation, viability, and exit from the bone marrow and is essential for rejection of melanoma lung metastasis.
Natural killer (NK) cell maturation is a tightly controlled p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b860525cde67b84693ae3c9db75d196
http://jem.rupress.org/cgi/pmidlookup?view=long&pmid=26503444

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T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow

Autor: Satoru Takahashi, Thierry Walzer, Fabrice Faure, Immo Prinz, Simon de Bernard, Keigyou Yoh, Emilie Debien, Jacqueline Marvel, Uzma Hasan, Thomas Henry, Laurent Buffat, Jacques Bienvenu, Sébastien Viel, Emily Charrier, Katia Mayol, Cécile Daussy, Georg Gasteiger

Publikováno v: Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2014, 211 (3), pp.563-77. ⟨10.1084/jem.20131560⟩
Journal of Experimental Medicine, 2014, 211 (3), pp.563-77. ⟨10.1084/jem.20131560⟩
The Journal of Experimental Medicine

Mutually exclusive expression of T-bet and Eomes drives the development of distinct NK cell lineages with complementary functions.
Trail+DX5−Eomes− natural killer (NK) cells arise in the mouse fetal liver and persist in the adult liver. Thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c991a55587367025b726be8e4d23b1
https://hal.archives-ouvertes.fr/hal-00972070

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Immune adaptive microenvironment profiles in intracerebral and intrasplenic lymphomas share common characteristics

Autor: Sylvain Fisson, Claire Galand, Wolf H. Fridman, Sabrina Donnou, Cécile Daussy, Lucile Crozet, Catherine Sautès-Fridman

Publikováno v: Clinical and experimental immunology. 165(3)

Summary A large body of evidence indicates that the immune microenvironment controls tumour development. Primary central nervous system lymphomas (PCNSL) are aggressive tumours growing in the central nervous system (CNS). To evaluate the role and cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b994b3dba4890c122ddec89c232c4ca6
https://pubmed.ncbi.nlm.nih.gov/21668435

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Defective IL10 signaling defining a subgroup of patients with inflammatory bowel disease

Autor: Julien Verdier, Danielle Canioni, Frank M. Ruemmele, Nadine Cerf-Bensussan, Virginie Verkarre, Frédéric Rieux-Laucat, Olivier Goulet, Cécile Daussy, A. Morali, Jean-Pierre Hugot, Alain Fischer, Bernadette Bègue, Christoph Klein, Bénédicte Pigneur

Publikováno v: The American journal of gastroenterology. 106(8)

Objectives Early onset inflammatory bowel diseases (EO-IBD) developing during the first year of life are likely to reflect inherited defects in key mechanism(s) controlling intestinal homeostasis, as recently suggested for interleukin 10 (IL10). Thus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d97baa1138b59eaf3db5697e902aadd
https://pubmed.ncbi.nlm.nih.gov/21519361

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Critical role of monocytes to support normal B cell and diffuse large B cell lymphoma survival and proliferation

Autor: Charlotte Boix, Thierry Jo Molina, Emilie M. Fournier, Christopher G. Mueller, Cécile Daussy, Wolf H. Fridman, Wing-Hong Kwan

Publikováno v: Journal of Leukocyte Biology
Journal of Leukocyte Biology, Society for Leukocyte Biology, 2007, 82 (3), pp.567-75 val UPR9021. ⟨10.1189/jlb.0706481⟩
Journal of Leukocyte Biology, 2007, 82 (3), pp.567-75 val UPR9021. ⟨10.1189/jlb.0706481⟩

Large B cell lymphomas can comprise numerous CD14+ cells in the tumor stroma, which raises the question of whether monocytes can support B cell survival and proliferation. We show that the coculture of monocytes with B cells from peripheral blood or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b535884816c251940b4b56af19dc6a07
https://hal.archives-ouvertes.fr/hal-00165353

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