Výsledky vyhledávání - "Cæcilie Skejø"

Akademický článek

Lymphocyte activation gene 3 is increased and affects cytokine production in rheumatoid arthritis

Autor: Janni Maria Pedersen, Aida Solhøj Hansen, Cæcilie Skejø, Kristian Juul-Madsen, Peter Junker, Kim Hørslev-Petersen, Merete Lund Hetland, Kristian Stengaard-Pedersen, Mikkel Østergaard, Bjarne Kuno Møller, Lene Dreyer, Ellen-Margrethe Hauge, Malene Hvid, Stinne Greisen, Bent Deleuran

Publikováno v: Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-13 (2023)

Abstract Background Lymphocyte activation gene-3 (LAG-3) inhibits T cell activation and interferes with the immune response by binding to MHC-II. As antigen presentation is central in rheumatoid arthritis (RA) pathogenesis, we studied aspects of LAG-

Externí odkaz: https://doaj.org/article/583e0f379e924c61b83a8eea2acef059

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Akademický článek

Tumor necrosis factor alpha neutralization attenuates immune checkpoint inhibitor-induced activation of intermediate monocytes in synovial fluid mononuclear cells from patients with inflammatory arthritis

Autor: Anne Sofie Sørensen, Morten Nørgaard Andersen, Kristian Juul-Madsen, Amalie Dyrelund Broksø, Cæcilie Skejø, Henrik Schmidt, Thomas Vorup-Jensen, Tue Wenzel Kragstrup

Publikováno v: Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-14 (2022)

Abstract Objective During treatment with immune checkpoint inhibitors (ICI) such as the anti-PD-1 antibody pembrolizumab, half of patients with pre-existing inflammatory arthritis experience disease flares. The underlying immunological mechanisms hav

Externí odkaz: https://doaj.org/article/6687f6d0e54d462c8755110d24f567a9

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Editorial: safety of ustekinumab in pregnancy-are we there yet?

Autor: Cæcilie Skejø, Thea Vestergaard, Mette Julsgaard

Publikováno v: Skejø, C, Vestergaard, T & Julsgaard, M 2022, ' Editorial : safety of ustekinumab in pregnancy-are we there yet? ', Alimentary Pharmacology and Therapeutics, vol. 55, no. 4, pp. 495-496 . https://doi.org/10.1111/apt.16767

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd572e53ce5d867cc4267ef2123eda2
https://pubmed.ncbi.nlm.nih.gov/34907546

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Juvenile idiopathic arthritis:lymphocyte activation gene-3 is a central immune receptor in children with oligoarticular subtypes

Autor: Stinne Ravn Greisen, Seza Ozen, Cæcilie Skejø, E. Sag, Maithri Prasad Aspari, Egemen Turhan, Selcan Demir, Morten Aagaard Nielsen, Malene Hvid, Bent Deleuran, Yelda Bilginer

Publikováno v: Sag, E, Demir, S, Aspari, M, Nielsen, M A, Skejø, C, Hvid, M, Turhan, E, Bilginer, Y, Greisen, S, Ozen, S & Deleuran, B 2021, ' Juvenile idiopathic arthritis : lymphocyte activation gene-3 is a central immune receptor in children with oligoarticular subtypes ', Pediatric Research, vol. 90, no. 4, pp. 744-751 . https://doi.org/10.1038/s41390-021-01588-2

Background: We investigated the role of inhibitory receptors (IRs) and especially lymphocyte activation gene-3 (LAG-3) in the pathogenesis of oligoarticular juvenile idiopathic arthritis (o-JIA). Methods: Paired samples of synovial fluid (SF) and pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4eff2c4b389590b41ebdd72ae37b9c
https://pure.au.dk/portal/da/publications/juvenile-idiopathic-arthritis(2e30bf0c-6605-421e-99d2-8e9ca61a55a0).html

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Juvenile idiopathic arthritis: lymphocyte activation gene-3 is a central immune receptor in children with oligoarticular subtypes

Autor: Erdal, Sag, Selcan, Demir, Maithri, Aspari, Morten Aagaard, Nielsen, Cæcilie, Skejø, Malene, Hvid, Egemen, Turhan, Yelda, Bilginer, Stinne, Greisen, Seza, Ozen, Bent, Deleuran

Publikováno v: Pediatric research. 90(4)

We investigated the role of inhibitory receptors (IRs) and especially lymphocyte activation gene-3 (LAG-3) in the pathogenesis of oligoarticular juvenile idiopathic arthritis (o-JIA).Paired samples of synovial fluid (SF) and plasma and peripheral blo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f13219c9cfb8676f97e91438a540f696
https://pubmed.ncbi.nlm.nih.gov/34031570

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SAT0006 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN 3 (TIM-3) IS INCREASED IN ACTIVE RHEUMATOID ARTHRITIS AND ASSOCIATED WITH CLINICAL DISEASE ACTIVITY AND RADIOGRAPHIC PROGRESSION

Autor: Peter Junker, Mette Deleuran, Morten Aagaard Nielsen, Malene Hvid, Merete Lund Hetland, Kristian Stengaard-Pedersen, Stinne Ravn Greisen, Cæcilie Skejø, Mikkel Ǿstergaard, Bent Deleuran, Aida S. Hansen, Kim Hørslev-Petersen

Publikováno v: SATURDAY, 15 JUNE 2019.

Background: Co-inhibitory receptors are important for the regulation of inflammation in autoimmune diseases. Among these, T-cell Immunoglobulin and mucin domain-3 (Tim-3) has recently gained attention, as it is expressed on exhausted T cells co-expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b02a55b03c63c8e71969f72925782a5c
https://doi.org/10.1136/annrheumdis-2019-eular.4614

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OP0130 IN VITRO CHARACTERIZATION OF INFLAMMATORY ARTHRITIS ASSOCIATED WITH IMMUNE CHECK POINT INHIBITION

Autor: Thomas Vorup-Jensen, M. Nørgaard Andersen, Anne Sørensen, Tue Wenzel Kragstrup, H. Schmidt, Kristian Juul-Madsen, Cæcilie Skejø

Publikováno v: Annals of the Rheumatic Diseases. 79:85.1-85

Background:During cancer treatment with immune checkpoint inhibitors (ICI) such as the anti-PD-1 antibody pembrolizumab, 2-4% of patients develop inflammatory arthritis as an immune related adverse event and half of patients with pre-existing inflamm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e2b54545e9b54e1f33cd13f91a7aefc
https://doi.org/10.1136/annrheumdis-2020-eular.1356

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