Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Cársky J"'
Autor:
Ivan Herčko, Cársky J
Publikováno v:
Acta Metallurgica Slovaca, Vol 21, Iss 4 (2015)
Based on Empress Maria Theresa’s order (of December 13, 1762) the first higher school institution specialised in technical education in Europe with the Department of Chemistry, Mineralogy and Metallurgy was founded in Schemnitz (present-day Banská
Autor:
Olga Ulicna, Liptáková A, M Sivonova, Zuzana Országhová, Zdenka Durackova, Cársky J, Ol’ga Vančová, Jana Muchová, Bozek P
Publikováno v:
General Physiology and Biophysics. 28:347-355
Oxidative damage is considered to play an important role in the pathogenesis of several diseases, such as diabetes mellitus (DM), atherosclerosis, cardiovascular complications and chronic renal failure. DM is associated with the oxidative stress and
Publikováno v:
Toxicology in Vitro. 20:868-873
Background: Pyridoxylidene aminoguanidine is an appropriate inhibitor of protein glycation, respectively formation of advanced glycation products, which are connected with mechanism of pathogenesis in chronic diabetic complications. Moreover, it was
Publikováno v:
Pharmacological reports : PR. 67(3)
Background β-Resorcylidene aminoguanidine (RAG), a highly reactive derivative of aminoguanidine, possesses antithrombotic activity which involves the activation of the vascular COX-2/PGI 2 pathway. This endothelium-dependent effect suggests that RAG
Autor:
Cársky J, Iveta Garaiova, Tison P, Jana Muchová, Zuzana Országhová, Zdenka Durackova, Liptáková A
Publikováno v:
Diabetic Medicine. 16:74-78
Summary Aims To examine the effect of Type 2 diabetes mellitus (DM) on enzymes of importance for oxygen-dependent killing of microorganisms by leucocytes. Methods Twenty patients with Type 2 DM and 20 nondiabetic controls provided blood samples for a
Publikováno v:
Toxicological & Environmental Chemistry. 57:163-170
The Schiff‐base aminoguanidine compounds including a resorcylidene aminoguanidine copper(II) complex that were synthesized at our laboratory posses non‐mutagenic properties when tested with Ames test using Salmonella typhimurium TA97, TA100 and T
Autor:
Marek Nocun, Cezary Watala, Piotr Kazmierczak, Iveta Waczulíková, Jerzy Gebicki, Cársky J, Olga Ulicna, Marcin Dobaczewski, Stefan Chlopicki, Ingrid Zitnanova, Zdena Durackova
Publikováno v:
Vascular pharmacology. 51(4)
There is good evidence supporting the notion that aminoguanidine(AG)-derived compounds prevent glycation/glycooxidation-dependent processes and therefore inhibit late diabetic complications. The aim of the present work was to analyse the antithrombot
Autor:
Cezary Watala, Tomasz Przygodzki, Magdalena Labieniec, Cársky J, Dominika Malinska, Jacek Rysz
Publikováno v:
Chemico-biological interactions. 179(2-3)
In the present investigation, we attempted to study possible mechanisms of the interactions of resorcylidene aminoguanidine (RAG), the agent with a recognized anti-glycation and antioxidative activity, with rat liver mitochondria. We hypothesized tha
Autor:
Pagácová E, Cársky J, Vanda Repiská, Braxatorisová T, Duríková M, V. Geislerova, Vojtassák J, Milan Blaško, Daniel Böhmer, Lubos Danisovic
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 25(1)
The potential genotoxi activity of chemical substances in vitro is usually assessed by the micronucleustest and by kuryological analysis. Use of the fluorescent plus Giemsa ( FPC) technique is also recommended in the event that positive results are f
Publikováno v:
Bioelectrochemistry (Amsterdam, Netherlands). 55(1-2)
We estimated in vitro membrane fluidity gradient in erythrocytes (RBC) from diabetic patients, using a fluorescent dye 1,6-diphenyl-1,3,5-hexatriene (DPH). The rate constant of DPH incorporation (k) into the membranes was determined by fitting experi