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Autor:
Sylvia Müller, Manuel Grez, K Pietschmann, Dorle Hennig, Oliver H. Krämer, Gesine Bug, Thorsten Heinzel, Lisann Pelzl, Sebastian Drube, Christian Wichmann
Publikováno v:
British Journal of Cancer
Background: Transcriptional repression is a key mechanism driving leukaemogenesis. In acute promyelocytic leukaemia (APL), the fusion protein promyelocytic leukaemia-retinoic acid receptor-α fusion (PML-RARα) recruits transcriptional repressors to