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Publikováno v:
European Journal of Anaesthesiology. 15:297-303
Publikováno v:
Regional Anesthesia and Pain Medicine. 23:64-70
Publikováno v:
CNS Drugs. 8:189-198
Esterase hydrolysis is a metabolic pathway that can be exploited to increase the rate of metabolism and elimination and so reduce the duration of the pharmacodynamic effects of drugs. Previously applied to β-adrenergic blocking agents and muscle rel
Publikováno v:
Acta Anaesthesiologica Scandinavica. 40:948-952
The utility of preoperative ketorolac administration to reduce the intensity and duration of postoperative pain was compared with placebo in a randomized double-blind design of 60 ASA 1-2 patients scheduled for minor orthopaedic surgery. No opioids n
Publikováno v:
Acta Anaesthesiologica Scandinavica. 38:218-222
The difference in analgesic activity following lumbar (group I) or thoracic (group II) epidural administration of 50 micrograms sufentanil was studied after cholecystectomy. Fifteen patients in each group were evaluated for pain relief using a linear
Autor:
C, Vanlersberghe, F, Camu
Publikováno v:
Handbook of experimental pharmacology. (182)
The hypnotic agent propofol has pharmacokinetic characteristics that allow for rapid onset and offset of drug effect and fast elimination from the body. Elderly patients show a greater sensitivity to the hypnotic effect of propofol. The drug is exten
Autor:
C. Vanlersberghe, Frederic Camu
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783540728139
It is today generally accepted that anesthetics act by binding directly to sensitive target proteins. For certain intravenous anesthetics, such as propofol, barbiturates, and etomidate, the major target for anesthetic effect has been identified as th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7319fb5267fb3e9525f6a15bc096523
https://biblio.vub.ac.be/vubir/etomidate-and-other-nonbarbiturates(fe7cb1b5-2b39-462d-9774-7e44eff2beea).html
https://biblio.vub.ac.be/vubir/etomidate-and-other-nonbarbiturates(fe7cb1b5-2b39-462d-9774-7e44eff2beea).html
Autor:
C. Vanlersberghe, Frederic Camu
Systemic administration of analgesic drugs is still the most widely used method for providing pain relief in acute painful situations. Opioids may be selected on the basis of their physicochemical characteristics and their diffusion index to the brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c17bd72e10a527bf8639acaa3d63a7c
https://hdl.handle.net/20.500.14017/2704ca52-4531-4302-8b85-0915ef41af44
https://hdl.handle.net/20.500.14017/2704ca52-4531-4302-8b85-0915ef41af44
Publikováno v:
Acta anaesthesiologica Belgica. 52(1)
The cyclooxygenase enzymes produce large amounts of prostaglandins in presence of tissue injury and inflammation. Prostaglandins exert their influence on nerve membrane excitability both at the peripheral site and at the spinal dorsal horn. Their key