Zobrazeno 1 - 10 of 304 pro vyhledávání: '"C, Trope"'
1
Akademický článek
A comparison of DNA repair pathways to achieve a site-specific gene modification of the Bruton's tyrosine kinase gene
Autor: David H. Gray, Jasmine Santos, Alexandra Grace Keir, Isaac Villegas, Simon Maddock, Edward C. Trope, Joseph D. Long, Caroline Y. Kuo
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 505-516 (2022)
Gene editing utilizing homology-directed repair has advanced significantly for many monogenic diseases of the hematopoietic system in recent years but has also been hindered by decreases between in vitro and in vivo gene integration rates. Homology-d
Externí odkaz: https://doaj.org/article/a50a2f85a4cc440a980c27bee1ffed02
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4
Akademický článek
The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism.
Autor: Briana R Flaherty, Yuxiao Wang, Edward C Trope, Tienhuei G Ho, Vasant Muralidharan, Eileen J Kennedy, David S Peterson
Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0129239 (2015)
Drug resistance poses a significant threat to ongoing malaria control efforts. Coupled with lack of a malaria vaccine, there is an urgent need for the development of new antimalarials with novel mechanisms of action and low susceptibility to parasite
Externí odkaz: https://doaj.org/article/3ff185045f204a87b4fa0ed3fe741960
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5
The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism
Autor: Edward C. Trope, David S. Peterson, Vasant Muralidharan, Yuxiao Wang, Eileen J. Kennedy, Tienhuei G. Ho, Briana R. Flaherty
Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0129239 (2015)
Drug resistance poses a significant threat to ongoing malaria control efforts. Coupled with lack of a malaria vaccine, there is an urgent need for the development of new antimalarials with novel mechanisms of action and low susceptibility to parasite
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe6ba982f260973b0c47a5a12a12066
https://pubmed.ncbi.nlm.nih.gov/26010880
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6
Long-term follow-up confirms a survival advantage of the paclitaxel–cisplatin regimen over the cyclophosphamide–cisplatin combination in advanced ovarian cancer
Autor: M. J. Piccart, K. Bertelsen, G. Stuart, J. Cassidy, C. Mangioni, E. Simonsen, K. James, S. Kaye, I. Vergote, R. Blom, R. Grimshaw, R. Atkinson, K. Swenerton, C. Trope, M. Nardi, J. Kaern, S. Tumolo, P. Timmers, J.-A. Roy, F. Lhoas, B. Lidvall, M. Bacon, A. Birt, J. Andersen, B. Zee, J. Paul, S. Pecorelli, B. Baron, W. Mcguire
Publikováno v: International Journal of Gynecologic Cancer. 13:144-148
Two independent and consecutive randomized clinical trials, conducted by the American Gynecological Oncology Group and by an European–Canadian Intergroup, have shown superiority, in clinical response rate, progression-free survival, and overall sur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52763297b4a3ee7fd72097b8fc750cda
https://doi.org/10.1136/ijgc-00009577-200311001-00003
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8
Ovarian cancer stage IIIC. Consequences of treatment level on overall and progression-free survival
Autor: H, Oksefjell, B, Sandstad, C, Trope
Publikováno v: European journal of gynaecological oncology. 27(3)
Maximum cytoreduction at primary surgery has been found to be one of the strongest prognostic factors for survival of ovarian cancer. The aim of the study was to investigate the influence of hospital level (primary vs secondary care centre), number a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96ed8ff84af76eec00cfb759d93a04f6
https://pubmed.ncbi.nlm.nih.gov/16800244
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10
Akademický článek
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