Zobrazeno 1 - 10
of 1 402
pro vyhledávání: '"C, Tomlinson"'
Autor:
Alexander Gilerson, Mateusz Malinowski, Jacopo Agagliate, Eder Herrera-Estrella, Maria Tzortziou, Michelle C. Tomlinson, Andrew Meredith, Richard P. Stumpf, Michael Ondrusek, Lide Jiang, Menghua Wang
Publikováno v:
Frontiers in Marine Science, Vol 11 (2024)
Coastal waters require monitoring of chlorophyll-a concentration (Chl-a) in a wide range of Chl-a from a few mg/m3 to hundreds of mg/m3, which is of interest to the fisheries industry, evaluation of climate change effects, ecological modeling and det
Externí odkaz:
https://doaj.org/article/c5a1b6be5cfa431898aa47c8a79e1423
Autor:
Sophie E. Roberts, Heather L. Martin, Danah Al-Qallaf, Anna A. Tang, Christian Tiede, Thembaninkosi G. Gaule, Albor Dobon-Alonso, Ross Overman, Sachin Shah, Hadrien Peyret, Keith Saunders, Robin Bon, Iain W. Manfield, Sandra M. Bell, George P. Lomonossoff, Valerie Speirs, Darren C. Tomlinson
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110461- (2024)
Summary: Monoclonal antibodies have revolutionized therapies, but non-immunoglobulin scaffolds are becoming compelling alternatives owing to their adaptability. Their ability to be labeled with imaging or cytotoxic compounds and to create multimeric
Externí odkaz:
https://doaj.org/article/afbbfa1f915d4d408b05c261d3880b47
Autor:
R. Mohamed-Ahmed, C. Tomlinson, A. Taithongchai, A. Rantell, G. Araklitis, D. Robinson, L. Cardozo
Publikováno v:
Continence, Vol 9, Iss , Pp 101066- (2024)
Introduction:: Overactive bladder (OAB) affects 27% of women in the UK with an adverse impact on quality of life. Medical treatment with anticholinergics has a high discontinuation rate due to side effects. OnabotulinumtoxinA (BOTOX ®) is an establi
Externí odkaz:
https://doaj.org/article/5acc833060d34463a7bc42560d151207
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1040 (2024)
Src homology 3 (SH3) domains play a critical role in mediating protein–protein interactions (PPIs) involved in cell proliferation, migration, and the cytoskeleton. Despite their abundance in the human proteome, the functions and molecular interacti
Externí odkaz:
https://doaj.org/article/09656d7271eb4a709813154e06a09ec5
Autor:
Jilian Xiong, Jian Shen, Qubin Qin, Michelle C. Tomlinson, Yinglong J. Zhang, Xun Cai, Fei Ye, Linlin Cui, Margaret R. Mulholland
Publikováno v:
Limnology and Oceanography Letters, Vol 8, Iss 3, Pp 498-508 (2023)
Abstract Climate change and nutrient pollution contribute to the expanding global footprint of harmful algal blooms. To better predict their spatial distributions and disentangle biophysical controls, a novel Lagrangian particle tracking and biologic
Externí odkaz:
https://doaj.org/article/2e23e76bed2b440582cd153bb0c8ff59
Autor:
Heather L. Martin, Amy L. Turner, Julie Higgins, Anna A. Tang, Christian Tiede, Thomas Taylor, Sitthinon Siripanthong, Thomas L. Adams, Iain W. Manfield, Sandra M. Bell, Ewan E. Morrison, Jacquelyn Bond, Chi H. Trinh, Carolyn D. Hurst, Margaret A. Knowles, Richard W. Bayliss, Darren C. Tomlinson
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113184- (2023)
Summary: Kinases are important therapeutic targets, and their inhibitors are classified according to their mechanism of action, which range from blocking ATP binding to covalent inhibition. Here, a mechanism of inhibition is highlighted by capturing
Externí odkaz:
https://doaj.org/article/602d6e2e2cea4be1917c7c7c7b34ebd6
Autor:
Roberta Freitas-Lemos, Devin C. Tomlinson, Yu-Hua Yeh, Candice L. Dwyer, Hongying Daisy Dai, Adam Leventhal, Allison N. Tegge, Warren K. Bickel
Publikováno v:
Preventive Medicine Reports, Vol 35, Iss , Pp 102280- (2023)
Despite being a major threat to health, vaccine hesitancy (i.e., refusal or reluctance to vaccinate despite vaccine availability) is on the rise. Using a longitudinal cohort of young adults (N = 1260) from Los Angeles County, California we investigat
Externí odkaz:
https://doaj.org/article/ee21b352d3264629a4bb285aa98dae17
Autor:
Warren K. Bickel, Devin C. Tomlinson, William H. Craft, Manxiu Ma, Candice L. Dwyer, Yu-Hua Yeh, Allison N. Tegge, Roberta Freitas-Lemos, Liqa N. Athamneh
Publikováno v:
Addiction Neuroscience, Vol 6, Iss , Pp 100068- (2023)
This systematic review aims to characterize the utility of machine learning to identify the predictors of smoking cessation outcomes and identify the machine learning methods applied in this area. In the current study, multiple searches occurred thro
Externí odkaz:
https://doaj.org/article/9b58aec1e6e345008c091dbd0af03f41
Autor:
Peng Liu, Sophie Roberts, James T Shoemaker, Jelena Vukasinovic, Darren C Tomlinson, Valerie Speirs
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283044 (2023)
3D cell culture models of cancer are currently being developed to recapitulate in vivo physiological conditions and to assess therapeutic responses. However, most models failed to incorporate the biochemical and biophysical stimuli from fluid flow. I
Externí odkaz:
https://doaj.org/article/a1f3233e463f4959a479de1b5e0033e3
Autor:
Jack A. Caudwell, Jordan M. Tinkler, Ben R.G. Johnson, Kenneth J. McDowall, Fayez Alsulaimani, Christian Tiede, Darren C. Tomlinson, Steven Freear, W. Bruce Turnbull, Stephen D. Evans, Jonathan A.T. Sandoe
Publikováno v:
Biofilm, Vol 4, Iss , Pp 100074- (2022)
Staphylococcus aureus (S. aureus) is an important human pathogen and a common cause of bloodstream infection. The ability of S. aureus to form biofilms, particularly on medical devices, makes treatment difficult, as does its tendency to spread within
Externí odkaz:
https://doaj.org/article/d1f78f448c774844abf1c65ef9338d66