Zobrazeno 1 - 10
of 1 301
pro vyhledávání: '"C, Tapia"'
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-33 (2024)
Abstract Background Although RNA-seq data are traditionally used for quantifying gene expression levels, the same data could be useful in an integrated approach to compute genetic distances as well. Challenges to using mRNA sequences for computing ge
Externí odkaz:
https://doaj.org/article/8337ce37fc1d4edb998fedc36164a029
Autor:
Francisco Rodas, Jetzabel A. Vidal-Vidal, Daniela Herrera, David A. Brown-Brown, Diego Vera, Joaquín Veliz, Pilar Püschel, José I. Erices, Verónica Sánchez Hinojosa, Julio C. Tapia, Eduardo Silva-Pavez, Claudia Quezada-Monrás, Pablo Mendoza-Soto, Flavio Salazar-Onfray, Cristian Carrasco, Ignacio Niechi
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Gallbladder cancer (GBC) is a prevalent and deadly biliary tract carcinoma, often diagnosed at advanced stages with limited treatment options. The 5-year survival rate varies widely from 4 to 60%, mainly due to differences in dise
Externí odkaz:
https://doaj.org/article/dbab4179d4a748d7bef2277a241ba50f
Autor:
Pablo Pérez-Moreno, Ismael Riquelme, Carolina Bizama, Luis Vergara-Gómez, Julio C. Tapia, Priscilla Brebi, Patricia García, Juan Carlos Roa
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6740 (2024)
Long non-coding RNAs (lncRNAs) are nucleotide sequences that participate in different biological processes and are associated with different pathologies, including cancer. Long intergenic non-protein-coding RNA 662 (LINC00662) has been reported to be
Externí odkaz:
https://doaj.org/article/ae01bf7a0cf4409c95595237c633710e
Autor:
Edio Maldonado, Paz Canobra, Matías Oyarce, Fabiola Urbina, Vicente J. Miralles, Julio C. Tapia, Christian Castillo, Aldo Solari
Publikováno v:
Microorganisms, Vol 12, Iss 5, p 907 (2024)
Chagas disease is caused by the single-flagellated protozoan Trypanosoma cruzi, which affects several million people worldwide. Understanding the signal transduction pathways involved in this parasite’s growth, adaptation, and differentiation is cr
Externí odkaz:
https://doaj.org/article/1505753e82db4edd9bed7ad3297d0f5e
Autor:
Dania Cataldo, Guillermo Aravena, Alejandro Escobar, Julio C. Tapia, Oscar A. Peralta, Cristian G. Torres
Publikováno v:
Animals, Vol 14, Iss 8, p 1229 (2024)
Mammary cancer is a frequent disease in female dogs, where a high proportion of cases correspond to malignant tumors that may exhibit drug resistance. Within the mammary tumor microenvironment, there is a cell subpopulation called cancer stem cells (
Externí odkaz:
https://doaj.org/article/4c0802bb75d246588475ab51af51c6e1
Autor:
Sebastián Morales-Pison, Julio C. Tapia, Sarai Morales-González, Edio Maldonado, Mónica Acuña, Gloria M. Calaf, Lilian Jara
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16076 (2023)
Cancer is a genomic disease, with driver mutations contributing to tumorigenesis. These potentially heritable variants influence risk and underlie familial breast cancer (BC). This study evaluated associations between BC risk and 13 SNPs in driver ge
Externí odkaz:
https://doaj.org/article/ed9bd84ab891405d95454b1962e458c0
Autor:
Sebastian Morales-Pison, Patricio Gonzalez-Hormazabal, Julio C. Tapia, Alexis Salas-Burgos, Sandra Ampuero, Fernando Gómez, Enrique Waugh, José Miguel Reyes, Lilian Jara
Publikováno v:
Biological Research, Vol 55, Iss 1, Pp 1-11 (2022)
Abstract Background Driver mutations are the genetic components responsible for tumor initiation and progression. These variants, which may be inherited, influence cancer risk and therefore underlie many familial cancers. The present study examines t
Externí odkaz:
https://doaj.org/article/05d1640173ac4906a08fe7b0724f4c1a
Autor:
Neudo Buelvas, Isidora Ugarte-Vio, Laura Asencio-Leal, Matías Muñoz-Uribe, Antonia Martin-Martin, Alejandro Rojas-Fernández, José A. Jara, Julio C. Tapia, María Elena Arias, Rodrigo A. López-Muñoz
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1383 (2023)
Indomethacin is a non-selective NSAID used against pain and inflammation. Although cyclooxygenase (COX) inhibition is considered indomethacin’s primary action mechanism, COX-independent ways are associated with beneficial effects in cancer. In colo
Externí odkaz:
https://doaj.org/article/dbca2459505846dbbdbb9e159dc7cac3
Autor:
Alvaro De la Mora, Nuria Morfin, José C. Tapia-Rivera, José O. Macías-Macías, José M. Tapia-González, Francisca Contreras-Escareño, Tatiana Petukhova, Ernesto Guzman-Novoa
Publikováno v:
Microorganisms, Vol 11, Iss 5, p 1258 (2023)
Honey bees (Apis mellifera L.) are affected by different biotic and abiotic stressors, such as the fungus Nosema ceranae and neonicotinoid insecticides, that negatively impact their health. However, most studies so far conducted have focused on the e
Externí odkaz:
https://doaj.org/article/98047a2f12da4ff6bf8a4cf367cfc7f7
Autor:
C. Halla, J. H. Blöthe, C. Tapia Baldis, D. Trombotto Liaudat, C. Hilbich, C. Hauck, L. Schrott
Publikováno v:
The Cryosphere, Vol 15, Pp 1187-1213 (2021)
The quantification of volumetric ice and water content in active rock glaciers is necessary to estimate their role as water stores and contributors to runoff in dry mountain catchments. In the semi-arid to arid Andes of Argentina, active rock glacier
Externí odkaz:
https://doaj.org/article/767ffc591f9c4c719db8de729449d86e