Disrupted sleep-wake regulation in the MCI-Park mouse model of Parkinson’s disease

Autor: K. C. Summa, P. Jiang, P. González-Rodríguez, X. Huang, X. Lin, M. H. Vitaterna, Y. Dan, D. J. Surmeier, F. W. Turek

Publikováno v: npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-9 (2024)

Abstract Disrupted sleep has a profound adverse impact on lives of Parkinson’s disease (PD) patients and their caregivers. Sleep disturbances are exceedingly common in PD, with substantial heterogeneity in type, timing, and severity. Among the most

Externí odkaz: https://doaj.org/article/6b9450931cf64148be60c36a1798d79e

A Prebiotic Diet Alters the Fecal Microbiome and Improves Sleep in Response to Sleep Disruption in Rats

Autor: Samuel J. Bowers, Keith C. Summa, Robert S. Thompson, Antonio González, Fernando Vargas, Christopher Olker, Peng Jiang, Christopher A. Lowry, Pieter C. Dorrestein, Rob Knight, Kenneth P. Wright, Monika Fleshner, Fred W. Turek, Martha H. Vitaterna

Publikováno v: Frontiers in Neuroscience, Vol 16 (2022)

Sleep disruption is a challenging and exceedingly common physiological state that contributes to a wide range of biochemical and molecular perturbations and has been linked to numerous adverse health outcomes. Modern society exerts significant pressu

Externí odkaz: https://doaj.org/article/225c36f354aa4d12b7a2ea0ef503e494

Contributors

Autor: Sabra M. Abbott, Takashi Abe, Imran I. Ali, J. Todd Arnedt, Alon Y. Avidan, Ronny P. Bartsch, Ruth M. Benca, Orfeu M. Buxton, Anne-Marie Chang, Ronald D. Chervin, Nancy Collop, Jennifer Corrigan, David F. Dinges, Emmanuel H. During, Mohan Dutt, Danny J. Eckert, Jack D. Edinger, E. Devon Eldridge-Smith, Chiara Formentin, Patrick M. Fuller, Jacqueline Geer, Cathy Goldstein, Patrick J. Hanly, Ronald M. Harper, Max Hirshkowitz, Michael J. Howell, Mary S.M. Ip, Muna Irfan, Plamen Ch. Ivanov, Shahrokh Javaheri, Sogol Javaheri, Christopher W. Jones, Yo-El S. Ju, Marc Kaizi-Lutu, Levente Kapas, Meir H. Kryger, Scott J. Kutscher, Won Y. Lee, Peter Y. Liu, Macy M.S. Lui, Bethany L. Lussier, Atul Malhotra, Raman K. Malhotra, Catherine A. McCall, William V. McCall, Wallace Mendelson, Sara Montagnese, Pier Luigi Parmeggiani, Aric A. Prather, Kathryn J. Reid, Thomas Roth, Logan Douglas Schneider, Colin M. Shapiro, Amir Sharafkhaneh, Ajaz A. Sheikh, Stephen H. Sheldon, Deena Sherman, Jerome M. Siegel, Andrea M. Spaeth, Robert Stickgold, Keith C. Summa, Leslie Swanson, Éva Szentirmai, Lauren Tobias, Fred W. Turek, Christopher D. Turnbull, Bradley V. Vaughn, Richard L. Verrier, Erin J. Wamsley, Sophie D. West, Daniel Whibley, John W. Winkelman, Brian S. Wojeck, Christine H.J. Won, Steven Yao, Kin M. Yuen, Phyllis C. Zee

Publikováno v: Atlas of Clinical Sleep Medicine ISBN: 9780323654036

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::930fd84484c707a8f8c13d92a7e499f1
https://doi.org/10.1016/b978-0-323-65403-6.00003-2

A Systems Approach Identifies Networks and Genes Linking Sleep and Stress: Implications for Neuropsychiatric Disorders

Autor: Peng Jiang, Joseph R. Scarpa, Karrie Fitzpatrick, Bojan Losic, Vance D. Gao, Ke Hao, Keith C. Summa, He S. Yang, Bin Zhang, Ravi Allada, Martha H. Vitaterna, Fred W. Turek, Andrew Kasarskis

Publikováno v: Cell Reports, Vol 11, Iss 5, Pp 835-848 (2015)

Sleep dysfunction and stress susceptibility are comorbid complex traits that often precede and predispose patients to a variety of neuropsychiatric diseases. Here, we demonstrate multilevel organizations of genetic landscape, candidate genes, and mol

Externí odkaz: https://doaj.org/article/7df3068f1f4e47d9a4cb04332748279b

Environmental perturbation of the circadian clock disrupts pregnancy in the mouse.

Autor: Keith C Summa, Martha Hotz Vitaterna, Fred W Turek

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e37668 (2012)

The circadian clock has been linked to reproduction at many levels in mammals. Epidemiological studies of female shift workers have reported increased rates of reproductive abnormalities and adverse pregnancy outcomes, although whether the cause is c

Externí odkaz: https://doaj.org/article/db1309f2532f4500a60a584bc865141e