Zobrazeno 1 - 10
of 77
pro vyhledávání: '"C, Stratowa"'
Autor:
W Spevak, M Wiche-Castanon, R Schafer, C Stratowa, U Weyer, A Himmler, H Machat, A P Czernilofsky, E Burger
Publikováno v:
Journal of Receptors and Signal Transduction. 15:617-630
The neurokinin receptor family is known to modulate phospholipase C activity. In order to find new compounds modulating the activity of these receptors we have developed a cellular screening system that measures the biological activity of receptors c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d678fab914dfa84a47ba8640b6508eb
https://doi.org/10.3109/10799899509045244
https://doi.org/10.3109/10799899509045244
Autor:
C, Stratowa, K K, Wilgenbus
Publikováno v:
Current opinion in molecular therapeutics. 1(6)
Recent advances in technology, especially the merger between molecular biology, automation technology and computer science, are rapidly changing the manner in which pharmaceutical companies will discover new drug targets and develop new therapeutic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6fc73d9c276f68403cecc7efddaa2e8b
https://pubmed.ncbi.nlm.nih.gov/19629863
https://pubmed.ncbi.nlm.nih.gov/19629863
Publikováno v:
The Journal of Immunology. 147:2777-2786
Human intercellular adhesion molecule-1 (ICAM-1), a specific ligand for the lymphocyte function-associated Ag-1 (LFA-1), plays an important role in leukocyte-endothelial cell interactions. It is induced by proinflammatory cytokines such as IL-1, TNF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c85d2aeaa6188a89ba5d12614667e38
https://doi.org/10.4049/jimmunol.147.8.2777
https://doi.org/10.4049/jimmunol.147.8.2777
Autor:
K Luber, Georg Weitzer, R Hauptmann, Gerhard Wiche, Murray Stewart, C Stratowa, M J Castañon, Bruno Becker
Publikováno v:
The Journal of Cell Biology
We have determined the complete cDNA sequence of rat plectin from a number of well-characterized overlapping lambda gt11 clones. The 4,140-residue predicted amino acid sequence (466,481 D) is consistent with a three-domain structural model in which a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e4ae59d26ee92daa5ab5af1d9b86ba
https://doi.org/10.1083/jcb.114.1.83
https://doi.org/10.1083/jcb.114.1.83
Autor:
C, Stratowa, A, Baum, M J, Castañon, G, Dahmann, F, Himmelsbach, A, Himmler, G, Loeber, T, Metz, R, Schnitzer, F, Solca, W, Spevak, U, Tontsch, T, von Rüden
Publikováno v:
Anti-cancer drug design. 14(5)
Growth factor receptor tyrosine kinases (RTK) have been implicated in tumor growth, metastasis and angiogenesis, and are thus considered promising targets for therapeutic intervention in malignant diseases. We present a novel drug discovery strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71794078fee8f9ff26dcd03db34408d6
https://pubmed.ncbi.nlm.nih.gov/10766294
https://pubmed.ncbi.nlm.nih.gov/10766294
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 8(3)
Human intercellular adhesion molecule-1 (ICAM-1) plays an important role in immune responses as the major specific ligand for the beta2-integrins LFA-1 and Mac-1. During the inflammatory process, ICAM-1 expression is stimulated by various proinflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a78b96f3bff870f232570f3ab64f68ae
https://pubmed.ncbi.nlm.nih.gov/9056676
https://pubmed.ncbi.nlm.nih.gov/9056676
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(5)
Human intercellular adhesion molecule-1 (ICAM-1), a specific ligand for the leukocyte-function associated antigen-1 and for Mac-1, plays an important role in immune responses. ICAM-1 expression is regulated by various proinflammatory cytokines, phorb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9f8a020d2c993cfc105bc5da6e7454a
https://pubmed.ncbi.nlm.nih.gov/7647034
https://pubmed.ncbi.nlm.nih.gov/7647034
Publikováno v:
Journal of receptor research. 13(1-4)
A large number of G-protein coupled receptors are known to modulate adenylyl cyclase activity. In order to find new compounds modulating the activity of specific receptor subtypes we developed a cellular screening system that measures the biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b83702b4fb7f50d30ef7e889f4bbf00
https://pubmed.ncbi.nlm.nih.gov/8383768
https://pubmed.ncbi.nlm.nih.gov/8383768
Publikováno v:
Receptorschannels. 1(3)
A functional cellular assay system was developed for the detection of substances modulating the activity of G protein-coupled receptors, linked to the phospholipase C second messenger system. The human adenocarcinoma cell line A549 was transformed wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::844227ccde23cd79e6a88fc08abce7d1
https://pubmed.ncbi.nlm.nih.gov/7522900
https://pubmed.ncbi.nlm.nih.gov/7522900
Publikováno v:
Acta Physica Academiae Scientiarum Hungaricae. 49:153-158
In the last years a series of measurements on weak-interaction in neutron decay has been performed using the coincidence detector developed byO. Benka. A short description of this detector will be presented with special emphasis on the problem of cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f526977fd3fb97d45d783705e9f1e23e
https://doi.org/10.1007/bf03158730
https://doi.org/10.1007/bf03158730