Zobrazeno 1 - 10
of 206
pro vyhledávání: '"C, Settembre"'
Autor:
Michael Cheung, Cheng Chang, Raveen Rathnasinghe, Evan Rossignol, Yunfei Zhang, Annette Ferrari, Harsh Patel, Yanjun Huang, Michelle Sanchez Guillen, Tina Scalzo, Changkeun Lee, Gillis R. Otten, Ethan C. Settembre, Nedzad Music, Giuseppe Palladino, Yingxia Wen
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Currently licensed influenza vaccines focus immune responses on viral hemagglutinin (HA), while the other major surface glycoprotein neuraminidase (NA) is not tightly controlled in inactivated vaccine formulations despite evidence that anti-
Externí odkaz:
https://doaj.org/article/34eefbdcbdca47e4b9effcc04a79f050
Autor:
Cheng Chang, Nedzad Music, Michael Cheung, Evan Rossignol, Sukhmani Bedi, Harsh Patel, Mohammad Safari, Changkeun Lee, Gillis R. Otten, Ethan C. Settembre, Giuseppe Palladino, Yingxia Wen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 195-205 (2022)
Vaccines are the primary intervention against influenza. Currently licensed inactivated vaccines focus immunity on viral hemagglutinin (HA). Self-amplifying mRNA (sa-mRNA) vaccines offer an opportunity to generate immunity to multiple viral proteins,
Externí odkaz:
https://doaj.org/article/912ad34f33834057b76e58f148316bfd
Autor:
Giuseppe Palladino, Cheng Chang, Changkeun Lee, Nedzad Music, Ivna De Souza, Jonathan Nolasco, Samuel Amoah, Pirada Suphaphiphat, Gillis R. Otten, Ethan C. Settembre, Yingxia Wen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 225-235 (2022)
The spike (S) protein of SARS-CoV-2 plays a crucial role in cell entry, and the nucleocapsid (N) protein is highly conserved among human coronavirus homologs. For potentially broad effectiveness against both original virus and emerging variants, we d
Externí odkaz:
https://doaj.org/article/f78df334f83d4554ba745ba254900e27
Autor:
Cheng Chang, Nedzad Music, Michael Cheung, Evan Rossignol, Sukhmani Bedi, Harsh Patel, Mohammad Safari, Changkeun Lee, Gillis R. Otten, Ethan C. Settembre, Giuseppe Palladino, Yingxia Wen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 11- (2023)
Externí odkaz:
https://doaj.org/article/f42ddb960d474101a8756cdd0d6e57e5
Autor:
Rhiannon R. Penkert, Sumana Chandramouli, Philip R. Dormitzer, Ethan C. Settembre, Robert E. Sealy, Susan Wong, Neal S. Young, Yilun Sun, Li Tang, Alyssa Cotton, Jola Dowdy, Randall T. Hayden, Jane S. Hankins, Julia L. Hurwitz
Publikováno v:
Vaccines, Vol 9, Iss 8, p 860 (2021)
Children with sickle cell disease (SCD) suffer life-threatening transient aplastic crisis (TAC) when infected with parvovirus B19. In utero, infection of healthy fetuses may result in anemia, hydrops, and death. Unfortunately, although promising vacc
Externí odkaz:
https://doaj.org/article/f7f113713a25483684b72228951921e3
Akademický článek
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Publikováno v:
Vaccine. 39:5351-5357
Vaccination is the most effective approach to reduce the substantial morbidity and mortality caused by influenza infection. Vaccine efficacy is highly sensitive to antigenic changes causing differences between circulating and vaccine viruses. Adjuvan
Akademický článek
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Akademický článek
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Autor:
Claudio Ciferri, Sumana Chandramouli, Alexander Leitner, Danilo Donnarumma, Michael A Cianfrocco, Rachel Gerrein, Kristian Friedrich, Yukti Aggarwal, Giuseppe Palladino, Ruedi Aebersold, Nathalie Norais, Ethan C Settembre, Andrea Carfi
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005230 (2015)
Human Cytomegalovirus (HCMV) is a major cause of morbidity and mortality in transplant patients and in fetuses following congenital infection. The glycoprotein complexes gH/gL/gO and gH/gL/UL128/UL130/UL131A (Pentamer) are required for HCMV entry in
Externí odkaz:
https://doaj.org/article/3a5daf217abf400db6ba314b6b613072