Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence

Autor: N Hamajima, K Hirose, K Tajima, T Rohan, CM Friedenreich, SM Gapstur, MM Gaudet, RJ Coates, JM Liff, E Kakouri, Y Marcou, SW Duffy, A Morabia, L Schuman, W Stewart, M Szklo, P Band, AJ Coldman, RP Gallagher, TG Hislop, P Yang, SR Cummings, J Hu, KC Johnson, Y Mao, P Chao, J Lissowska, K Canfell, PL Horn-Ross, LM Kolonel, AMY Nomura, T Bishop, D Palli, S De Sanjose, CA Gonzalez, N Lee, P Marchbanks, HW Ory, HB Peterson, P Wingo, K Ebeling, D Kunde, P Nishan, L Bergkvist, JL Hopper, F Sitas, S Franceschi, L Dal Maso, TH Chan, AH Eliassen, RM Tamimi, WC Willett, V Gajalakshmi, N Martin, T Pardthaisong, S Silpisornkosol, C Theetranont, B Boosiri, S Chutivongse, P Jimakorn, P Virutamasen, C Wongsrichanalai, A Neugut, R Santella, A Hadjisavvas, K Kyriacou, M Loizidou, CJ Baines, N Kreiger, AB Miller, C Wall, A Tjonneland T Jorgensen, C Stahlberg, A T0nnes Pedersen, E Negri, SE Hankinson, D Flesch-Janys, C La Vecchia, N Hakansson, I Heuch, HO Adami, E Weiderpass, A Ekbom, G Erlandsson, I Persson, C Magnusson, L Jones, K McPherson, A Neil, M Vessey, D Yeates, G Berry, J Cooper Booth, T Jelihovsky, R MacLennan, J Chang-Claude, R Kaaks, M Iwasaki, S Tsugane, GL Anderson, JR Daling, WB Hutchinson, CI Li, KE Malone, M Mandelson, PA Newcomb, EA Noonan, RM Ray, JL Stanford, MTC Tang, DB Thomas, NS Weiss, E White, A Izquierdo, P Viladiu, KM Egan, HR Cuevas, P Ontiveros, A Palet, SB Salazar, N Aristizabal, A Cuadros, L Tryggvadottir, EJ Olafsdottir, E Riboli, N Andrieu, A Bachelot, A Bremond, B Gairard, J Lansac, MG Le, L Piana, R Renaud, MC Boutron-Ruault, N Chabbert-Buffet, F Clavel-Chapelon, A Fournier, S Mesrine, F Levi, M Jones, AJ Swerdlow, A Wolk, K Kosmelj, M Primic-Zakelj, J Stare, G Torres-Mejia, I Romieu, P Boyle, F Lubin, B Modan, E Ron, Y Wax, M Ferraroni, E Marubini, EM Monninkhof, NC Onland-Moret, PHM Peeters, GD Friedman, RA Hiatt, M Touillaud, WL Beeson, G Fraser, J Peto, RL Hanson, MC Leske, MC Mahoney, PC Nasca, AO Varma, AL Weinstein, RA Goldbohm, PA van den Brandt, N Chantarakul, S Koetsawang, D Rachawat, MC Pike, M Gerber, S Richardson, C Segala, S Teitelbaum, D Gatei, P Kenya, A Kungu, JG Mati, LA Brinton, M Freedman, R Hoover, C Schairer, RG Ziegler, E Banks, R Spirtas, HP Lee, MA Rookus, FE van Leeuwen, JA Schoenberg, S Graff-Iversen, R Selmer, S Atkinson, I Barnes, V Beral, D Bull, T Gathani, A Goodill, J Green, C Hermon, T Key, K Pirie, G Reeves, K Shaw, TO Yang, R Collins, HC Pan, R Peto, R Ghiasvand, K Mabuchi, D Preston, SE McCann, P Hannaford, C Kay, JM Hampton, LJ Titus, A Trentham-Dietz, B Liu, YT Gao, F Jin, J-M Yuan, HY Wei, T Yun, C Zhiheng, PF Coogan, JR Palmer, L Rosenberg, EM John, Q-S Wang, M Kawai, Y Minami, I Tsuji, M Kumle, H Stalsberg, E Lund, EO Fourkala, I Jacobs, U Menon, A Ryan, L Hartman, H Olsson, K Katsouyanni, A Trichopoulou, A Tzonou, KA Baltzell, A Dabancens, L Martinez, R Molina, O Salas, L Rosero-Bixby, FE Alexander, K Anderson, AR Folsom, MD Gammon, BS Hulka, R Millikan, CED Chilvers, M McCredie, C Paul, DCG Skegg, GFS Spears, F Lumachi, TR Rebbeck, RA Apelo, J Baens, JR de la Cruz, B Javier, LB Lacaya, CA Ngelangel, J Cauley, for the Study of Osteoporotic Fractures, C Bain, F Schofield, V Siskind, L Bernstein, S Enger, RW Haile, A Paganini-Hill, G Ursin, AH Wu, MC Yu, M Ewertz, EA Clarke, XO Shu, W Zheng, M Gass, MJ O’Sullivan, A Kalache, TMM Farley, S Holck, O Meirik, A Fukao, X Zhou

Publikováno v: Lancet, 394(10204), 1159-1168. Elsevier Science

Background: Published findings on breast cancer risk associated with different types of menopausal hormone therapy (MHT) are inconsistent, with limited information on long-term effects. We bring together the epidemiological evidence, published and un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439d0f8027a6f9d2226fb0e42b5966f1
https://cris.maastrichtuniversity.nl/en/publications/88a75911-ca7a-43e6-91a1-ba6c24758e34

Assessment and Treatment of Psychiatric Distress, Sexual Dysfunction, Sleep Disturbances, and Pain in Multiple Sclerosis

Autor: Eliana Pasternak, Elizabeth S. Gromisch, Laura C. Schairer, Frederick W. Foley, Stella H. Kim

Publikováno v: International Journal of MS Care. 18:291-297

Background: Psychiatric distress (depression and anxiety), sexual dysfunction, sleep disturbances, and pain are frequent comorbidities in multiple sclerosis (MS) that have the potential to interfere with functioning and quality of life. Often, patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d81537ce358753e14ae14ba09498e70
https://doi.org/10.7224/1537-2073.2016-007

The impact of sexual dysfunction on health-related quality of life in people with multiple sclerosis

Autor: Tuula Tyry, Laura C. Schairer, Denise I. Campagnolo, Elizabeth S. Gromisch, Ruth Ann Marrie, David Schairer, Frederick W. Foley, Vance Zemon

Publikováno v: Multiple Sclerosis Journal. 20:610-616

Background: Sexual dysfunction is a prevalent symptom in multiple sclerosis (MS) that may affect patients’ health-related quality of life (HrQoL). Objective: The objective of this paper is to examine the impact of sexual dysfunction on HrQoL in a l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a355359d7d24ee20cb2ba127035809
https://doi.org/10.1177/1352458513503598

Assessing the criterion validity of four highly abbreviated measures from the Minimal Assessment of Cognitive Function in Multiple Sclerosis (MACFIMS)

Autor: Mary Ann Picone, Roee Holtzer, Frederick W. Foley, Nancy D. Chiaravalloti, Elizabeth S. Gromisch, Eileen Farrell, Vance Zemon, Stacey Snyder, Jessica Sloan, Laura C. Schairer, Jason Botvinick, Meghan Beier, John DeLuca, Lisa Glukhovsky, Sonya Kim

Publikováno v: The Clinical neuropsychologist. 30(7)

Cognitive dysfunction is prevalent in multiple sclerosis. As self-reported cognitive functioning is unreliable, brief objective screening measures are needed. Utilizing widely used full-length neuropsychological tests, this study aimed to establish t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855a3915d871f222feac9889c511eb53
https://pubmed.ncbi.nlm.nih.gov/27279357

Inhibitors of hepatitis C virus NS3·4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics

Autor: Cynthia A. Gates, Kai Lin, Govinda Rao, Murcko Mark A, Chao Lin, John H. Van Drie, Yunyi Wei, John Maxwell, Wayne C. Schairer, Gurudatt Chandorkar, Kevin M. Cottrell, Janos Pitlik, Robert B. Perni, Yu-Ping Luong

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 17:3406-3411

Reversible tetrapeptide-based compounds have been shown to effectively inhibit the hepatitis C virus NS3.4A protease. Inhibition of viral replicon RNA production in Huh-7 cells has also been demonstrated. We show herein that the inclusion of hydrogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdfc4cf3109ab7123b112b53c078f21
https://doi.org/10.1016/j.bmcl.2007.03.090