Zobrazeno 1 - 10 of 74 pro vyhledávání: '"C, Roolf"'
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Akademický článek
Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines
Autor: L.-M. Sklarz, Y. S. Gladbach, M. Ernst, M. Hamed, C. Roolf, S. Sender, J. Beck, E. Schütz, S. Fischer, S. Struckmann, C. Junghanss, G. Fuellen, H. Murua Escobar
Publikováno v: Cancer Cell International, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background The introduction of combined conventional cytostatics and pathway-specific inhibitors has opened new treatment options for several cancer types including hematologic neoplasia such as leukaemias. As the detailed understanding of t
Externí odkaz: https://doaj.org/article/b57c4052d3ff44699e1ea56403b7ff78
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2
Akademický článek
Decitabine demonstrates antileukemic activity in B cell precursor acute lymphoblastic leukemia with MLL rearrangements
Autor: C. Roolf, A. Richter, C. Konkolefski, G. Knuebel, A. Sekora, S. Krohn, J. Stenzel, B. J. Krause, B. Vollmar, H. Murua Escobar, C. Junghanss
Publikováno v: Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-13 (2018)
Abstract Background Promotor hypermethylation of CpG islands is common in B cell precursor acute lymphoblastic leukemia (BCP-ALL) with mixed lineage leukemia (MLL) gene rearrangements. Hypomethylating agents (HMA) such as azacitidine (AZA) and decita
Externí odkaz: https://doaj.org/article/45601950b7b64166967ef05f6a062b47
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8
Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines
Autor: L-M, Sklarz, Y S, Gladbach, M, Ernst, M, Hamed, C, Roolf, S, Sender, J, Beck, E, Schütz, S, Fischer, S, Struckmann, C, Junghanss, G, Fuellen, H, Murua Escobar
Publikováno v: Cancer Cell International
Background The introduction of combined conventional cytostatics and pathway-specific inhibitors has opened new treatment options for several cancer types including hematologic neoplasia such as leukaemias. As the detailed understanding of the combin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::98bf44e035189759dc1406b46dbced4d
https://pubmed.ncbi.nlm.nih.gov/32817744
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