Výsledky vyhledávání - "C, Paraskeva"

Akademický článek

Isolation of Purified High Added Value Products from Olive Mill Wastewater Streams through the Implementation of Membrane Technology and Cooling Crystallization Process

Autor: S. Kontos, I. Iakovides, P. Koutsoukos, C. Paraskeva

Publikováno v: Chemical Engineering Transactions, Vol 47 (2016)

Olive Mill Wastewater (OMW) and olive leaves are the main by-product associated with olive oil production. OMW is a by-product characterized by the very high concentration of organics and phenolic compounds rendering its biodegradability very difficu

Externí odkaz: https://doaj.org/article/6433b11e377f41b98974abdfba93051d

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Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis

Autor: Owen J. Sansom, Clare Bagley, Tracey J Collard, C Paraskeva, Paul Martin, Karim Malik, Kate J. Heesom, Alexander Greenhough, Ann C. Williams, David B Gurevich, Mark Bond

Publikováno v: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 10, Iss 11, Pp n/a-n/a (2018)
Greenhough, A, Bagley, C, Heesom, K, Gurevich, D, Gay, D, Bond, M, Collard, T, Paraskeva, C, Martin, P, Sansom, O J, Malik, K & Williams, A 2018, ' Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis ', EMBO Molecular Medicine, vol. 10, no. 11, e8699 . https://doi.org/10.15252/emmm.201708699

Hypoxia is a hallmark of solid tumours and a key physiological feature distinguishing cancer from normal tissue. However, a major challenge remains in identifying tractable molecular targets that hypoxic cancer cells depend on for survival. Here, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246b42e86a556838dc6eabdbcb0bb84f
https://eprints.gla.ac.uk/168162/1/168162.pdf

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BCL-3 enhances β-catenin signalling in colorectal tumour cells promoting a cancer stem cell phenotype

Autor: Alex P. Shephard, Tracey J Collard, C Paraskeva, Adam C. Chambers, Ann C. Williams, Danny Legge, Richard W. E. Clarkson, Alexander Greenhough

Increased nuclear BCL-3 (a key regulator of inflammation and NF-κB signalling when associated with p50 or p52 homodimers) has been reported in a subset of colorectal cancers, but its role in colorectal tumorigenesis remains poorly understood. Intere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a438120c1d68e697d36dd78021eb3608
https://doi.org/10.1101/178004

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Rapid Decline in HIV Incidence among Persons Who Inject Drugs during a Fast-Track Combination Prevention Program after an HIV Outbreak in Athens

Autor: Sypsa, V. Psichogiou, M. Paraskevis, D. Nikolopoulos, G. Tsiara, C. Paraskeva, D. Micha, K. Malliori, M. Pharris, A. Wiessing, L. Donoghoe, M. Friedman, S. Jarlais, D.D. Daikos, G. Hatzakis, A.

Background. A "seek-test-treat" intervention (ARISTOTLE) was implemented in response to an outbreak of human immunodeficiency virus (HIV) infection among persons who inject drugs (PWID) in Athens. We assess trends in HIV incidence, prevalence, risk b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::be10de84c19ee392199b6175110a5a80
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3108662

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β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells

Autor: Catherine A. Cherry, John M. Mariadason, Joerg Huelsken, Alan Richard Clarke, Lee Parry, Heather R. Roberts, Helena J M Smartt, Paloma Ordóñez-Morán, C Paraskeva, Ann C. Williams, Manal Al Al Kharusi, Elena Talero, Alexander Greenhough, Catherine A. Wallam

Publikováno v: Gut. 61:1306-1314

BACKGROUND: Cyclooxygenase-2 (COX-2) overexpression in colorectal cancer increases levels of its pro-tumorigenic product prostaglandin E2 (PGE(2)). The recently identified colorectal tumour suppressor 15-prostaglandin dehydrogenase (15-PGDH) catalyse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9571fafb62b1ca02843170d1a92c56c0
https://doi.org/10.1136/gutjnl-2011-300817

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The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE2 signalling in colorectal adenoma cells

Autor: C Paraskeva, Ann C. Williams, Diane J. Hicks, Moganaden Moorghen, Catherine A. Wallam, Alexander Greenhough

Publikováno v: Oncogene

Overexpression of cyclooxygenase-2 (COX-2) and elevated levels of its enzymatic product prostaglandin E2 (PGE(2)) occur in the majority of colorectal cancers and have important roles in colorectal tumorigenesis. However, despite the established prosu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb324ef1c259b437278044f2a08c8cd
https://doi.org/10.1038/onc.2010.94

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Study of LiMgVO4 electrical conductivity mechanism

Autor: A. Kazakopoulos, C. Paraskeva, Orestis Kalogirou, Konstantinos Chrissafis

Publikováno v: Journal of Alloys and Compounds. 489:714-718

This paper deals with impedance spectroscopy on single-phase polycrystalline LiMgVO 4 in the temperature range of 25–500 °C. Thermogravimetric measurements show a weight loss of 2.7% in the temperature range between 25 °C and 175 °C due to humid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b36dd9fa2c5ce085d730f14e433fcc83
https://doi.org/10.1016/j.jallcom.2009.09.159

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Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer

Autor: Evan M. Kroh, Andrew M. Kaz, Sanford D. Markowitz, Jun Ho Lee, April Allen, Patrick S. Mitchell, Young Ho Kim, Brian R. Fritz, James K V Willson, Rachael K. Parkin, Mary Kay Washington, William M. Grady, Muneesh Tewari, C Paraskeva, Karen D. Tsuchiya

Publikováno v: Oncogene. 27:3880-3888

MicroRNAs are small, non-coding RNAs that influence gene regulatory networks by post-transcriptional regulation of specific messenger RNA targets. MicroRNA expression is dysregulated in human malignancies, frequently leading to loss of expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec581619584491f5a1ce0dfb946fdb3d
https://doi.org/10.1038/onc.2008.10

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Circulating prostaglandins as biomarkers for colorectal cancer?

Autor: C Paraskeva, Ann C. Williams, Alexander Greenhough

Publikováno v: EBioMedicine
EBioMedicine, Vol 2, Iss 2, Pp 105-106 (2015)

Background Colorectal cancer (CRC) represents the third leading cause of cancer-related death in the United States. Lack of reliable biomarkers remains a critical issue for early detection of CRC. In this study, we investigated the potential predicti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19b7e48434d3d20d23e27c897b08218
https://pubmed.ncbi.nlm.nih.gov/25750933

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