Zobrazeno 1 - 10
of 470
pro vyhledávání: '"C, Orban"'
Autor:
Carmen L. Bayly, Xiao-Qing Dai, Cuilan Nian, Paul C. Orban, C. Bruce Verchere, Patrick E. MacDonald, Francis C. Lynn
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102017- (2024)
Objective: Human embryonic stem cell (hESC; SC)-derived pancreatic β cells can be used to study diabetes pathologies and develop cell replacement therapies. Although current differentiation protocols yield SCβ cells with varying degrees of maturati
Externí odkaz:
https://doaj.org/article/fec9a33079604cce9f9fa718f5adb276
Autor:
C. Orban, S. Lener, H. Koller, R. Gmeiner, A. Abramovic, M. Konschake, W. Schmölz, S. Hartmann, C. Thomé
Publikováno v:
Brain and Spine, Vol 4, Iss , Pp 103945- (2024)
Externí odkaz:
https://doaj.org/article/3e98427eae9741ea8a2a0e5f0246e160
Autor:
R. Gmeiner, H. Koller, A. Abramovic, S. Lener, C. Orban, M. Konschake, W. Schmölz, C. Thomé, S. Hartmann
Publikováno v:
Brain and Spine, Vol 4, Iss , Pp 103950- (2024)
Externí odkaz:
https://doaj.org/article/0b3eecba257c4d9795bed590d3f96b76
Autor:
V. Hubertus, L. Viezens, M. Stangenberg, R. Liang, A. Kramer, C. Orban, J. Kerschbaumer, B. Kunze, S. Telera, A. Früh, H. Miller, C.J. Entenmann, T. Keller, D. Kaul, J. Krönke, I.W. Blau, U. Keller, F. Ringel, C. Thomé, H.S. Meyer, M. Dreimann, B. Meyer, P. Vajkoczy, J.S. Onken
Publikováno v:
Brain and Spine, Vol 4, Iss , Pp 104054- (2024)
Externí odkaz:
https://doaj.org/article/97a30a4f19474851b22da3abecdf6141
Publikováno v:
Brain and Spine, Vol 4, Iss , Pp 104056- (2024)
Externí odkaz:
https://doaj.org/article/25c4be81bc5a408fab9f8ab969549698
Autor:
Justin A. Spanier, Vivian Fung, Christine M. Wardell, Mohannad H. Alkhatib, Yixin Chen, Linnea A. Swanson, Alexander J. Dwyer, Matthew E. Weno, Nubia Silva, Jason S. Mitchell, Paul C. Orban, Majid Mojibian, C. Bruce Verchere, Brian T. Fife, Megan K. Levings
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 18 (2023)
Adoptive immunotherapy with Tregs is a promising approach for preventing or treating type 1 diabetes. Islet antigen–specific Tregs have more potent therapeutic effects than polyclonal cells, but their low frequency is a barrier for clinical applica
Externí odkaz:
https://doaj.org/article/07b12edb27a645e0ba884c7c896ee39b
Autor:
Austin J. Taylor, Evgeniy Panzhinskiy, Paul C. Orban, Francis C. Lynn, David F. Schaeffer, James D. Johnson, Janel L. Kopp, C. Bruce Verchere
Publikováno v:
Molecular Metabolism, Vol 68, Iss , Pp 101667- (2023)
Objectives: Pancreatic cancer risk is elevated approximately two-fold in type 1 and type 2 diabetes. Islet amyloid polypeptide (IAPP) is an abundant beta-cell peptide hormone that declines with diabetes progression. IAPP has been reported to act as a
Externí odkaz:
https://doaj.org/article/3b960dd09db649a3b0d27836178a6bad
Publikováno v:
Brain and Spine, Vol 2, Iss , Pp 101380- (2022)
Externí odkaz:
https://doaj.org/article/ce67992bcc2645e89ca904f1e6d90b05
Autor:
Hamid R. Razzaghian, Zohreh Sharafian, Ashish A. Sharma, Guilaine K. Boyce, Kelsey Lee, Rachel Da Silva, Paul C. Orban, Rafick-Pierre Sekaly, Colin J. Ross, Pascal M. Lavoie
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Newborns are frequently affected by mucocutaneous candidiasis. Th17 cells essentially limit mucosal invasion by commensal Candida spp. Here, we sought to understand the molecular basis for the developmental lack of Th17 cell responses in circulating
Externí odkaz:
https://doaj.org/article/28208e0f99b54cc9b66ac58a41238d23
Publikováno v:
Brain and Spine, Vol 1, Iss , Pp 100419- (2021)
Externí odkaz:
https://doaj.org/article/4d40e53253574330831bbd54132e4005