Zobrazeno 1 - 10
of 885
pro vyhledávání: '"C, Neville"'
Publikováno v:
Chemistry, Vol 5, Iss 3, Pp 1998-2008 (2023)
Herein, we report the expansion of chemical space available from chitin, accessible via the biogenic N-platforms 3A5AF, M4A2C, and di-HAF. The biologically active heteroaromatics furo[3,2-d]pyrimidin-4-one and furo[3,2-d]pyrimidin-4-amine can be sele
Externí odkaz:
https://doaj.org/article/1510400c97d44963a76c6519b40b64aa
Publikováno v:
Annals of Surgery Open, Vol 4, Iss 3, p e301 (2023)
Objective:. With the increased global prevalence of older people with dementia, more will present for surgery over the coming decades. Therefore, the objective of this study was to synthesize the existing research about how pain in managed for people
Externí odkaz:
https://doaj.org/article/58f2400c568744bcbd40258d6c9fad82
Autor:
Thomas R. W. Oliver, Lia Chappell, Rashesh Sanghvi, Lauren Deighton, Naser Ansari-Pour, Stefan C. Dentro, Matthew D. Young, Tim H. H. Coorens, Hyunchul Jung, Tim Butler, Matthew D. C. Neville, Daniel Leongamornlert, Mathijs A. Sanders, Yvette Hooks, Alex Cagan, Thomas J. Mitchell, Isidro Cortes-Ciriano, Anne Y. Warren, David C. Wedge, Rakesh Heer, Nicholas Coleman, Matthew J. Murray, Peter J. Campbell, Raheleh Rahbari, Sam Behjati
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The molecular characterisation of germ cell tumours (GCT) is necessary to understand their development and histological diversification. Here, the authors use whole-genome and transcriptome sequencing of GCTs across distinct histologies to reveal the
Externí odkaz:
https://doaj.org/article/a04dee3f9628403093fe2d0a118a0411
Autor:
Arjun Rajan, Lucas Anhezini, Noemi Rives-Quinto, Jay Y Chhabra, Megan C Neville, Elizabeth D Larson, Stephen F Goodwin, Melissa M Harrison, Cheng-Yu Lee
Publikováno v:
eLife, Vol 12 (2023)
Coordinated regulation of gene activity by transcriptional and translational mechanisms poise stem cells for a timely cell-state transition during differentiation. Although important for all stemness-to-differentiation transitions, mechanistic unders
Externí odkaz:
https://doaj.org/article/66c1d0c26bf94422a25197895b76c7fa
Publikováno v:
Heliyon, Vol 8, Iss 10, Pp e10862- (2022)
Claudin-4, a protein with the structure of classic claudins most often found in cell-cell junctions, is frequently overexpressed in epithelial cancers where its localization has not been studied. In this study we aimed to find out where this membrane
Externí odkaz:
https://doaj.org/article/a41d0d5f72c1467789792a7d3777359f
Autor:
Hilary C. Martin, Eugene J. Gardner, Kaitlin E. Samocha, Joanna Kaplanis, Nadia Akawi, Alejandro Sifrim, Ruth Y. Eberhardt, Ana Lisa Taylor Tavares, Matthew D. C. Neville, Mari E. K. Niemi, Giuseppe Gallone, Jeremy McRae, Deciphering Developmental Disorders Study, Caroline F. Wright, David R. FitzPatrick, Helen V. Firth, Matthew E. Hurles
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Developmental disorders (DDs) are more prevalent in males, thought to be due to X-linked genetic variation. Here, the authors investigate the burden of X-linked coding variants in 11,044 DD patients, showing that this contributes to ~6% of both male
Externí odkaz:
https://doaj.org/article/97934482d6eb4ef4a62a77b65cc8aafa
Autor:
Margaret C. Neville, Ellen W. Demerath, Jennifer Hahn-Holbrook, Russell C. Hovey, Jayne Martin-Carli, Mark A. McGuire, Edward R. Newton, Kathleen M. Rasmussen, Michael C. Rudolph, Daniel J. Raiten
Publikováno v:
The American Journal of Clinical Nutrition. 117:S11-S27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea7debe3c7cfc5c1ee4e0f933a01c708
https://doi.org/10.1016/j.ajcnut.2022.11.026
https://doi.org/10.1016/j.ajcnut.2022.11.026
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009468 (2021)
Doublesex (Dsx) and Fruitless (Fru) are the two downstream transcription factors that actuate Drosophila sex determination. While Dsx assists Fru to regulate sex-specific behavior, whether Fru collaborates with Dsx in regulating other aspects of sexu
Externí odkaz:
https://doaj.org/article/93ef57dbd7c34c08a959ff57cebf8e92
Publikováno v:
Cell Reports, Vol 33, Iss 11, Pp 108516- (2020)
Summary: Sexual dimorphism in Drosophila courtship circuits requires the male-specific transcription factor fruM, which is alternatively spliced to encode the FruMA, FruMB, and FruMC isoforms. Most fruM-positive neurons express multiple variants; how
Externí odkaz:
https://doaj.org/article/50365f12babb4edc85882be089dc0821
Publikováno v:
BMC Geriatrics, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Research highlights the need for carers of people with dementia to acquire relevant and timely information to assist them to access appropriate respite services. Unfortunately, negative experiences of information-seeking can creat
Externí odkaz:
https://doaj.org/article/8a9bd0a5723148db980bcec58c5c9d94