Zobrazeno 1 - 10
of 165
pro vyhledávání: '"C, Nachev"'
Publikováno v:
Journal of neurology. 269(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c203e4acb0069189f38cb8c2a1f7eb20
https://pubmed.ncbi.nlm.nih.gov/35094152
https://pubmed.ncbi.nlm.nih.gov/35094152
Autor:
Alberto Zanchetti, Willem H. Birkenhäger, Jaakko Tuomilehto, Gastone Leonetti, Patricia McCormack, Peter W. de Leeuw, Jan A. Staessen, Cinzia Sarti, Eoin O'Brien, Jose L. Rodicio, C Nachev, Joseph B. Rosenfeld, Françoise Forette, Christopher J. Bulpitt, John Webster, Hilde Celis, Astrid E. Fletcher, Lutgarde Thijs, Yair Yodfat, Robert Fagard
Publikováno v:
Journal of Hypertension. 22:847-857
Background To assess the impact of immediate versus delayed anti hypertensive treatment on the outcome of older patients with isolated systolic hypertension, we extended the double- blind placebo-controlled Systolic Hypertension in Europe (Syst- Eur)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3c9af51977fc1e1044adf4338060d1
https://doi.org/10.1097/00004872-200404000-00029
https://doi.org/10.1097/00004872-200404000-00029
Autor:
Jan A. Staessen, Lutgarde Thijs, Blas Gil-Extremera, D Dumitrascu, Christopher J. Bulpitt, Ruth Peters, Jonathan Cooke, Nigel Beckett, Maria do Carmo Pereira Nunes, C Nachev
Publikováno v:
Journal of Hypertension. 21:2409-2417
BACKGROUND: The risks and benefits of treating hypertension in individuals older than 80 years are uncertain. A meta-analysis has suggested that a reduction in stroke events of 36% may have to be balanced against a 14% increase in total mortality. OB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c478960fa50b3d6fae57c0a2fd74b37f
https://doi.org/10.1097/00004872-200312000-00030
https://doi.org/10.1097/00004872-200312000-00030
Autor:
Christopher J. Bulpitt, Jaakko Tuomilehto, Christopher Davidson, Lutgarde Thijs, Matti Jääskivi, John Webster, Eoin O'Brien, Robert Fagard, Jan A. Staessen, Edward Pringle, C Nachev, Gianfranco Parati, Peter W. de Leeuw, Charles Phillips
Publikováno v:
Journal of Hypertension. 21:2251-2257
OBJECTIVE: To investigate whether baseline systolic blood pressure variability was a risk factor for stroke, cardiovascular mortality or cardiac events during the Syst-Eur trial. DESIGN: The Syst-Eur study was a randomized, double-blind, placebo-cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd98b5f6a777eba4d2d0d1ce28761b80
https://doi.org/10.1097/00004872-200312000-00012
https://doi.org/10.1097/00004872-200312000-00012
Systolic Hypertension in Europe (Syst-Eur) Trial Phase 2: objectives, protocol, and initial progress
Autor:
C Nachev, P. W. De Leeuw, Lutgarde Thijs, Y Yodfat, A E Fletcher, Christopher J. Bulpitt, M. Safar, K Kawecka-Jaszcz, J Webster, Robert Fagard, J Rosenfeld, GG Arabidze, Hilde Celis, Jan A. Staessen, J Duggan, J Tuomilehto, Jerzy Gasowski, W. H. Birkenhäger, JL Rodicio, M.-L. Seux, CT Dollery, G Leonetti
Publikováno v:
Journal of Human Hypertension. 13:135-145
The Systolic Hypertension in Europe (Syst-Eur) trial proved that blood pressure (BP) lowering therapy starting with nitrendipine reduces the risk of cardiovascular complications in older (> or = 60 years) patients with isolated systolic hypertension
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0285ef6762d988f3c56c5cecd99ed9b8
https://doi.org/10.1038/sj.jhh.1000769
https://doi.org/10.1038/sj.jhh.1000769
Autor:
Peter W. de Leeuw, Robert Fagard, Aris D. Efstratopoulos, Astrid E. Fletcher, Guramy Arabidze, Blas Gil-Extremera, Lutgarde Thijs, M.L. Seux, Willem H. Birkenhäger, Kalina Kawecka-Jaszcz, Yair Yodfat, Matti Jääskivi, C Nachev, Jaakko Tuomilehto, Jan A. Staessen, Christopher J. Bulpitt, Roberto Fogari, Speranta Babeanu, John Webster, J C Petrie, Christopher Davidson
Publikováno v:
Hypertension. 32:410-416
Abstract —In the double-blind Systolic Hypertension in Europe (Syst-Eur) Trial, active treatment was initiated with nitrendipine (10 to 40 mg/d) with the possible addition of enalapril (5 to 20 mg/d) and/or hydrochlorothiazide (12.5 to 25 mg/d) tit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29db19b789909d240094292caef07d3d
https://doi.org/10.1161/01.hyp.32.3.410
https://doi.org/10.1161/01.hyp.32.3.410
Autor:
ET O'Brien, Willem H. Birkenhäger, Alberto Zanchetti, Lutgarde Thijs, P. W. De Leeuw, Joseph B. Rosenfeld, Jan A. Staessen, G G Arabidze, Robert Fagard, Jose L. Rodicio, Astrid E. Fletcher, Gastone Leonetti, Hilde Celis, Jaakko Tuomilehto, C Nachev, Colin T. Dollery, Françoise Forette, Christopher J. Bulpitt
Publikováno v:
The Lancet. 350:757-764
Summary Background Isolated systolic hypertension occurs in about 15% of people aged 60 years or older. In 1989, the European Working Party on High Blood Pressure in the Elderly investigated whether active treatment could reduce cardiovascular compli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e14d1c0d756202c04cdeaf7c29a6ec5d
https://doi.org/10.1016/s0140-6736(97)05381-6
https://doi.org/10.1016/s0140-6736(97)05381-6
Publikováno v:
Metal-Based Drugs
Zn(II) picolinate and aspartate, Zn(pic)2 and Zn(asp)2, have been shown to inhibit key steps of the replication of HSV-1. In the present study we describe the effect of Zn(pic)2 and Zn(asp)2 on the replication of VZV and on the infectivity of free vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509668414ea019ed9df522cfe0f2897f
https://doi.org/10.1155/mbd.1996.11
https://doi.org/10.1155/mbd.1996.11
Autor:
Stoyan Shishkov, D. Strachilov, Z. Paskalev, P. Bontchev, M. Panteva, C. Nachev, A. Toutekova, T.L. Varadinova
Publikováno v:
Journal of Chemotherapy. 5:3-9
SummaryThe influence of Zn-complexes with biologically active ligands like aminoacids: picolinic acid as Zn(pic)2 and asparaginic acid as Zn(asp)2 on HSV-1 infection in vitro was investigated. Studies on kinetics of Zn-ions using labeled 65Zn(pic)2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a909074bcf51827da4022b3ddb34ad60
https://doi.org/10.1080/1120009x.1993.11739200
https://doi.org/10.1080/1120009x.1993.11739200