Transparent reporting of adaptive clinical trials using concurrently randomised cohorts

Autor: Mark Jones, David Price, Jason Roberts, Joseph John, Tim Spelman, Thomas L Snelling, Vivekanand Jha, Steven Y C Tong, David Paterson, Balasubramanian Venkatesh, Naomi Hammond, James McFadyen, Robert Medcalf, Huyen Tran, Asha Bowen, Sanjeev Chunilal, Megan Rees, Joshua Davis, Justin Denholm, Susan Morpeth, Ian C Marschner, James McGree, James A Totterdell, Robert K Mahar, Bhupendra Basnet, Grace McPhee, Zoe McQuilten, Matthew O’Sullivan, Nanette Trask, Jennifer Curnow, Eileen Merriman, Todd Cooper, Julie Marsh

Publikováno v: BMJ Medicine, Vol 2, Iss 1 (2023)

Adaptive clinical trials have designs that evolve over time because of changes to treatments or changes to the chance that participants will receive these treatments. These changes might introduce confounding that biases crude comparisons of the trea

Externí odkaz: https://doaj.org/article/d5fb4ca321794c40b2977505be9d9985

Estimating age-specific COVID-19 fatality risk and time to death by comparing population diagnosis and death patterns: Australian data

Autor: Ian C. Marschner

Publikováno v: BMC Medical Research Methodology, Vol 21, Iss 1, Pp 1-10 (2021)

Abstract Background Mortality is a key component of the natural history of COVID-19 infection. Surveillance data on COVID-19 deaths and case diagnoses are widely available in the public domain, but they are not used to model time to death because the

Externí odkaz: https://doaj.org/article/b53c8bc1a5904ce081e34e94787ba896

Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration: protocol for a systematic review with individual participant data meta-analysis of behavioural interventions for the prevention of early childhood obesity

Autor: Finn Rasmussen, Hein Raat, Cristina Palacios, Barry J Taylor, Lisa Askie, Alison Hayes, Cindy-Lee Dennis, Karen Campbell, Wendy Smith, Luke Wolfenden, Sharleen O’Reilly, Eva Corpeleijn, Maria Bryant, Chris Rissel, Denise O’Connor, Paul Chadwick, Jessica Thomson, Anna Lene Seidler, Kylie E Hunter, Rachael W Taylor, Angie Barba, Kristy Robledo, Ken Ong, Carolina González Acero, Ana Pérez-Expósito, Kylie D Hesketh, Rebecca K Golley, David Espinoza, Ken K Ong, Sarah Taki, Rachael Taylor, Louise A Baur, Li Ming Wen, Seema Mihrshahi, Emily Oken, Barry Taylor, Ian Marschner, Junilla K Larsen, Kylie Hesketh, Rajalakshmi Lakshman, Amanda L Thompson, Sharleen L O'Reilly, Jonathan Williams, Charles Wood, Alison J Hayes, Kaumudi Joshipura, Hongping Xia, Lynne Daniels, Rebecca Byrne, Alison Karasz, Rebecca Golley, Kaumudi J Joshipura, Angela Webster, Nina Cecilie Øverby, Brittany J Johnson, Mason Aberoumand, Sol Libesman, Kristy P Robledo, Charles T Wood, Lukas P Staub, Michelle Sue-See, Ian C Marschner, Jessica L Thomson, Vera Verbestel, Sarah-Jeanne Salvy, Levie T Karssen, Finn E Rasmussen, Mary Jo Messito, Rachel S Gross, Ian M Paul, Heather M Wasser, Claudio Maffeis, Ata Ghaderi, Jinan C Banna, Maribel Campos Rivera, Ana B Pérez-Expósito, Jennifer S Savage, Margrethe Røed, Michael Goran, Kayla de la Haye, Stephanie Anzman-Frasca, Kylie Hunter, Brittany Johnson, Louise Baur, Lukas Staub, Shonna Yin, Lee Sanders, Amanda Thompson, Ana Maria Linares, Cathleen Odar Stough, Christine Helle, Eliana Perrin, Heather Wasser, Jinan Banna, Kayla dela Haye, Levie Karssen, Nina Øverby, Rachel Gross, Russell Rothman, Wendy A Smith, Alexander Fiks, Deborah Jacobvitz, Jennifer Savage Williams, Márcia Regina Vitolo, Elizabeth Widen

Publikováno v: BMJ Open, Vol 12, Iss 1 (2022)

Externí odkaz: https://doaj.org/article/091bcf02122241f490982c3cf8dab1fd

Parameter expansion for fitting regression models with non-negativity constraints

Autor: Mark W. Donoghoe, Ian C. Marschner

Publikováno v: Communications in Statistics - Simulation and Computation. :1-18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02c90f9bf4272738e4ae5e3b8590a880
https://doi.org/10.1080/03610918.2022.2154791

Analysis of adaptive platform trials using a network approach

Autor: Ian C Marschner, I Manjula Schou

Publikováno v: Clinical Trials. 19:479-489

Background Adaptive platform trials allow randomized controlled comparisons of multiple treatments using a common infrastructure and the flexibility to adapt key design features during the study. Nonetheless, they have been criticized due to the pote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d51216e2b0a964f949c3f0b8147cfd9
https://doi.org/10.1177/17407745221112001