Zobrazeno 1 - 10
of 101
pro vyhledávání: '"C, Le Goascogne"'
Publikováno v:
Journal of Cell Science. 113:4241-4251
A dynamic model for inducing and isolating polarized cell colonies from differentiated rat hepatoma was established with chenodeoxycholic acid (CDCA). Cells were treated with 75 microM CDCA in a 1% solvent mix (DMSO/ethanol: 0.5%/0.5%) for 11 days an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a6c7f418f3b78e89b3ddbed566537d
https://doi.org/10.1242/jcs.113.23.4241
https://doi.org/10.1242/jcs.113.23.4241
Publikováno v:
The Journal of Cell Biology
The rat central nervous system (CNS) has previously been shown to synthesize pregnenolone (PREG) and convert it to progesterone (PROG) and 7 alpha-hydroxy-PREG (7 alpha-OH PREG). Astrocytes, which participate to the regulation of the CNS function, mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628df6e12bdae138ad69074a39aadba3
https://doi.org/10.1083/jcb.121.1.135
https://doi.org/10.1083/jcb.121.1.135
Autor:
N. Sananès, M. Gouézou, C. Le Goascogne, Etienne-Emile Baulieu, S. Kominami, S. Takemori, Paul Robel
Publikováno v:
Reproduction. 93:609-622
The cytochrome P-450(17 alpha)-hydroxylase, 17----20 lyase (P-450(17 alpha)) is the key enzyme responsible for the biosynthesis of androgens in steroidogenic organs. Its cellular localization has been examined with an immunohistochemical technique. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d183b3fe74032b8037fd82de0c38c4b9
https://doi.org/10.1530/jrf.0.0930609
https://doi.org/10.1530/jrf.0.0930609
Publikováno v:
The European journal of neuroscience. 20(7)
Lesion of the sciatic nerve caused a rapid activation of p38MAP kinase in the injured nerve adjacent to the site of transection. This activation was detectable 3 min after lesioning, increased during the next 15 min and remained high for several hour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b607f6066f2e64461a883014d668c50
https://pubmed.ncbi.nlm.nih.gov/15380002
https://pubmed.ncbi.nlm.nih.gov/15380002
Publikováno v:
Neuroscience. 107(3)
Thyroid hormones are essential for the development and function of the brain and also for the maturation and repair of the peripheral nervous system. In the brain, most of the 3,5,3'-triiodothyronine is locally produced by 5'-deiodination of thyroxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7366143856b6c1ec398be2f9cc226992
https://pubmed.ncbi.nlm.nih.gov/11719005
https://pubmed.ncbi.nlm.nih.gov/11719005
Publikováno v:
Biology of reproduction. 58(2)
FKBP59 is an immunophilin that binds the immunosuppressant drugs FK506 and rapamycin. It is a 90-kDa heat shock protein (hsp90)-binding protein that was originally discovered as a member of steroid receptor complexes. FKBP59 is ubiquitous and well co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216e4e3df0e9ee5d0cce47bd0bb4af47
https://pubmed.ncbi.nlm.nih.gov/9475389
https://pubmed.ncbi.nlm.nih.gov/9475389
Publikováno v:
Endocrinology. 136(4)
Dehydroepiandrosterone (DHEA) and its conjugates persist in the rat brain, for up to 1 month after ablation of both adrenals and gonads. Since DHEA synthesis in brain from pregnenolone (PREG) was excluded, we have considered other tissular sources in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3a0d6ba37ac425ef57214bd6ff83c2
https://pubmed.ncbi.nlm.nih.gov/7895686
https://pubmed.ncbi.nlm.nih.gov/7895686
Autor:
A. N. Margioris, C. Stoumaras, Antonis Makrigiannakis, A. Gravanis, G. Nikas, C. Le Goascogne, A. Psychoyos, E. Zoumakis
Publikováno v:
Life sciences. 57(20)
We have shown previously that the epithelial cells of human endometrium produce CRH. The biological role of endometrial CRH is not yet known. Among other things, CRH appears to be involved in the inflammatory process, acting as an autocrine/paracrine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622b7a6b21296958069335601c6877db
https://pubmed.ncbi.nlm.nih.gov/7475934
https://pubmed.ncbi.nlm.nih.gov/7475934
Publikováno v:
The Journal of endocrinology. 139(1)
The testes of testicular feminized (Tfm) mice synthesize and secrete abnormally low amounts of testosterone, as a consequence of selectively decreased cytochrome P45017α activity. To investigate the mechanism of this deficiency, three steroidogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503ce1d60d56c0fd6fcdf9f39b48b162
https://pubmed.ncbi.nlm.nih.gov/8254285
https://pubmed.ncbi.nlm.nih.gov/8254285
Autor:
Do-Hyun Jo, K. Kabbadj, C. Le Goascogne, Jacques Young, Claire Vourc'h, Paul Robel, D. Zucman, C. Corpéchot, Zhong Yi Hu, Etienne-Emile Baulieu, Yvette Akwa, P. Simon, Ingrid Jung-Testas, M.J. Sancho
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 40(1-3)
Pregnenolone (P) and dehydroepiandrosterone (D) accumulate in the brain as unconjugated steroids and their sulfate (S) and fatty acid (L) esters. The microsomal acyl-transferase activity is highest in immature (1-3 weeks old) male rats. The immunocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02831a87caab806a2eb5089ec99bb7f3
https://pubmed.ncbi.nlm.nih.gov/1835645
https://pubmed.ncbi.nlm.nih.gov/1835645