Zobrazeno 1 - 10
of 89
pro vyhledávání: '"C, Jomary"'
Publikováno v:
Molecular Brain Research. 29:172-176
To define the relationship between progressive photoreceptor degeneration and clusterin upregulation, we analysed the spatio-temporal distribution and level of clusterin mRNA in the retinal degeneration (rd) mouse. Expression was increased in the ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97efdd46c718a0e183505eb7a07e0654
https://doi.org/10.1016/0169-328x(94)00252-a
https://doi.org/10.1016/0169-328x(94)00252-a
Publikováno v:
FEBS Letters. 352:171-174
To explore the molecular and cellular mechanisms associated with photoreceptor death in retinitis pigmentosa (RP), we have investigated altered transcriptional activity in RP retinas by a differential cDNA screening approach. We identified a clone (K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48fa8182577b3719902f1a2a9fd844d9
https://doi.org/10.1016/0014-5793(94)00951-1
https://doi.org/10.1016/0014-5793(94)00951-1
Publikováno v:
Molecular vision. 7
Neurturin (NTN) is a potent neuronal survival factor in the central and peripheral nervous systems. We previously described altered expression of mRNAs for NTN and one of its receptor components, GFRa-2 in degenerative retinas of rd/rd mice. Towards
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36c80994c0711caa2662059340d4fe0d
https://pubmed.ncbi.nlm.nih.gov/11239244
https://pubmed.ncbi.nlm.nih.gov/11239244
Publikováno v:
Investigative ophthalmologyvisual science. 41(6)
Inherited retinal degenerations such as retinitis pigmentosa (RP) are characterized by progressive death of the photoreceptors due to apoptosis. To identify changes in gene expression associated with the degenerative state in RP retinas, expression p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c84e9f38fa0af86420ec9bdbc9dafe1
https://pubmed.ncbi.nlm.nih.gov/10798643
https://pubmed.ncbi.nlm.nih.gov/10798643
Publikováno v:
Investigative ophthalmologyvisual science. 40(12)
High levels of expression of a form of gamma-crystallin mRNA in mouse retina have been identified. Because the six murine gamma-crystallins have generally been regarded as specific to the lens, the expression of these crystallins at the mRNA and prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0068685ea5fdfdaedba647d15e65f5d6
https://pubmed.ncbi.nlm.nih.gov/10549666
https://pubmed.ncbi.nlm.nih.gov/10549666
Publikováno v:
Investigative ophthalmologyvisual science. 40(3)
Neurturin (NTN) and its receptor components (GFRalpha2 and Ret) play an important role in the survival of different populations of neurons in the central and peripheral nervous systems. To gain insight into their possible functions throughout normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2d92aef629db6f1409e9228f5047f29
https://pubmed.ncbi.nlm.nih.gov/10067959
https://pubmed.ncbi.nlm.nih.gov/10067959
Publikováno v:
Gene therapy. 1
A possible route to the treatment of inherited retinal degenerations such as retinitis pigmentosa (RP) is the application of somatic gene therapy by the transfer and expression of corrective functional genes in ocular tissue. Cationic liposomes are e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5722e48ae3b98097dc6bf2c0d6cf99c
https://pubmed.ncbi.nlm.nih.gov/8542407
https://pubmed.ncbi.nlm.nih.gov/8542407
Publikováno v:
Brain research. Molecular brain research. 13(4)
Neuroanatomical data have documented the existence of synaptic contacts between γ-aminobutyric acid (GABA) terminals and periventricular hypothalamic somatostatin (SRIF) neurons. In other brain regions, like the cortex or hippocampus, GABA and SRIF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b88cdc043f15192091887ce2648392
https://pubmed.ncbi.nlm.nih.gov/1352611
https://pubmed.ncbi.nlm.nih.gov/1352611
Publikováno v:
FEBS Letters. (2-3):117-122
Adenovirus-mediated gene transfer to retinal cells was evaluated using the replication-defective recombinant adenovirus vector Ad2/CMVlacZ-1 (coding for beta-galactosidase) both in an in vitro murine culture model and in vivo in adult mice. In vitro,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0928fa78c5f0e53775875754e1a4d1a
Publikováno v:
NIDA research monograph. 75
Iodination of the kappa-selective peptide DPDYN, [D-Pro10]-dynorphin (1-11), has been performed. The non radioactive monoiodo derivative of DPDYN retains kappa-selectivity (kappa/mu = 48 and kappa/delta = 140), despite a general but moderate decrease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad290a61fa7e30bcdb3029467a1d5c02
https://pubmed.ncbi.nlm.nih.gov/2893266
https://pubmed.ncbi.nlm.nih.gov/2893266