Zobrazeno 1 - 10
of 413
pro vyhledávání: '"C, Hocke"'
Autor:
Nico Joel Halwe, Lea Hamberger, Julia Sehl-Ewert, Christin Mache, Jacob Schön, Lorenz Ulrich, Sten Calvelage, Mario Tönnies, Jonas Fuchs, Pooja Bandawane, Madhumathi Loganathan, Anass Abbad, Juan Manuel Carreño, Maria C. Bermúdez-González, Viviana Simon, Ahmed Kandeil, Rabeh El-Shesheny, Mohamed A. Ali, Ghazi Kayali, Matthias Budt, Stefan Hippenstiel, Andreas C. Hocke, Florian Krammer, Thorsten Wolff, Martin Schwemmle, Kevin Ciminski, Donata Hoffmann, Martin Beer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Influenza A viruses (IAVs) of subtype H9N2 have reached an endemic stage in poultry farms in the Middle East and Asia. As a result, human infections with avian H9N2 viruses have been increasingly reported. In 2017, an H9N2 virus was isolated
Externí odkaz:
https://doaj.org/article/27c9b3ce2fd746359b0b64d22dcabd10
Autor:
Umer Bin Abdul Aziz, Ali Saoud, Marcel Bermudez, Maren Mieth, Amira Atef, Thomas Rudolf, Christoph Arkona, Timo Trenkner, Christoph Böttcher, Kai Ludwig, Angelique Hoelzemer, Andreas C. Hocke, Gerhard Wolber, Jörg Rademann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Pneumolysin (PLY) is a cholesterol-dependent cytolysin (CDC) from Streptococcus pneumoniae, the main cause for bacterial pneumonia. Liberation of PLY during infection leads to compromised immune system and cytolytic cell death. Here, we repo
Externí odkaz:
https://doaj.org/article/d115b78ddffa4616af6f6aa528f3f42c
Autor:
Umer Bin Abdul Aziz, Ali Saoud, Marcel Bermudez, Maren Mieth, Amira Atef, Thomas Rudolf, Christoph Arkona, Timo Trenkner, Christoph Böttcher, Kai Ludwig, Angelique Hoelzemer, Andreas C. Hocke, Gerhard Wolber, Jörg Rademann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/a9c589d94a30489c8d0d88a9d47ad5a8
Autor:
Ronja Mothes, Anna Pascual-Reguant, Ralf Koehler, Juliane Liebeskind, Alina Liebheit, Sandy Bauherr, Lars Philipsen, Carsten Dittmayer, Michael Laue, Regina von Manitius, Sefer Elezkurtaj, Pawel Durek, Frederik Heinrich, Gitta A. Heinz, Gabriela M. Guerra, Benedikt Obermayer, Jenny Meinhardt, Jana Ihlow, Josefine Radke, Frank L. Heppner, Philipp Enghard, Helena Stockmann, Tom Aschman, Julia Schneider, Victor M. Corman, Leif E. Sander, Mir-Farzin Mashreghi, Thomas Conrad, Andreas C. Hocke, Raluca A. Niesner, Helena Radbruch, Anja E. Hauser
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Infection with SARS-CoV-2 has been linked with substantive inflammation, lung pathology and development of COVID-19. Here the authors spatially associate CCL18 and CCL21 in distinct tissue niches with lung pathology of severe COVID-19.
Externí odkaz:
https://doaj.org/article/1b2247b6d5234d329b89d09ddd2a8d84
Autor:
Wilhelm Bertrams, Katja Hönzke, Benedikt Obermayer, Mario Tönnies, Torsten T. Bauer, Paul Schneider, Jens Neudecker, Jens C. Rückert, Thorsten Stiewe, Andrea Nist, Stephan Eggeling, Norbert Suttorp, Thorsten Wolff, Stefan Hippenstiel, Bernd Schmeck, Andreas C. Hocke
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Influenza A virus (IAV) causes pandemics and annual epidemics of severe respiratory infections. A better understanding of the molecular regulation in tissue and cells upon IAV infection is needed to thoroughly understand pathogenesis. We ana
Externí odkaz:
https://doaj.org/article/c50c2cb466264e50b387903c6f1c25d3
Autor:
Kristin Köppen, Diana Fatykhova, Gudrun Holland, Jessica Rauch, Dennis Tappe, Mareike Graff, Kerstin Rydzewski, Andreas C. Hocke, Stefan Hippenstiel, Klaus Heuner
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionTularemia is mainly caused by Francisella tularensis (Ft) subsp. tularensis (Ftt) and Ft subsp. holarctica (Ftt) in humans and in more than 200 animal species including rabbits and hares. Human clinical manifestations depend on the route
Externí odkaz:
https://doaj.org/article/d6e9ebf52bbd4cc2a2203240deec7a4e
Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury
Autor:
Christian Hinze, Christine Kocks, Janna Leiz, Nikos Karaiskos, Anastasiya Boltengagen, Shuang Cao, Christopher Mark Skopnik, Jan Klocke, Jan-Hendrik Hardenberg, Helena Stockmann, Inka Gotthardt, Benedikt Obermayer, Laleh Haghverdi, Emanuel Wyler, Markus Landthaler, Sebastian Bachmann, Andreas C. Hocke, Victor Corman, Jonas Busch, Wolfgang Schneider, Nina Himmerkus, Markus Bleich, Kai-Uwe Eckardt, Philipp Enghard, Nikolaus Rajewsky, Kai M. Schmidt-Ott
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background Acute kidney injury (AKI) occurs frequently in critically ill patients and is associated with adverse outcomes. Cellular mechanisms underlying AKI and kidney cell responses to injury remain incompletely understood. Methods We perf
Externí odkaz:
https://doaj.org/article/2152453158884a80961272912072ce81
Autor:
Karen Hoffmann, Benedikt Obermayer, Katja Hönzke, Diana Fatykhova, Zeynep Demir, Anna Löwa, Luiz Gustavo Teixeira Alves, Emanuel Wyler, Elena Lopez-Rodriguez, Maren Mieth, Morris Baumgardt, Judith Hoppe, Theresa C. Firsching, Mario Tönnies, Torsten T. Bauer, Stephan Eggeling, Hong-Linh Tran, Paul Schneider, Jens Neudecker, Jens C. Rückert, Achim D. Gruber, Matthias Ochs, Markus Landthaler, Dieter Beule, Norbert Suttorp, Stefan Hippenstiel, Andreas C. Hocke, Mirjana Kessler
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
The GSK3 inhibitor CHIR99021 is required to maintain the alveolar lineage in alveolar progenitors grown in airway media or AT2 cells become plastic, with the observed effects acting outside of its role as a GSK3B inhibitor.
Externí odkaz:
https://doaj.org/article/04f4581a1d914ad59d4e1d253cb8de1e
Autor:
Morris Baumgardt, Maren Hülsemann, Anna Löwa, Diana Fatykhova, Karen Hoffmann, Mirjana Kessler, Maren Mieth, Katharina Hellwig, Doris Frey, Alina Langenhagen, Anne Voss, Benedikt Obermayer, Emanuel Wyler, Simon Dökel, Achim D Gruber, Ulf Tölch, Stefan Hippenstiel, Andreas C Hocke, Katja Hönzke
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294216 (2023)
[This corrects the article DOI: 10.1371/journal.pone.0276115.].
Externí odkaz:
https://doaj.org/article/27cd70b6b78d49fa83211a11aca3609c
Autor:
Daniela Niemeyer, Saskia Stenzel, Talitha Veith, Simon Schroeder, Kirstin Friedmann, Friderike Weege, Jakob Trimpert, Julian Heinze, Anja Richter, Jenny Jansen, Jackson Emanuel, Julia Kazmierski, Fabian Pott, Lara M Jeworowski, Ruth Olmer, Mark-Christian Jaboreck, Beate Tenner, Jan Papies, Felix Walper, Marie L Schmidt, Nicolas Heinemann, Elisabeth Möncke-Buchner, Morris Baumgardt, Karen Hoffmann, Marek Widera, Tran Thi Nhu Thao, Anita Balázs, Jessica Schulze, Christin Mache, Terry C Jones, Markus Morkel, Sandra Ciesek, Leif G Hanitsch, Marcus A Mall, Andreas C Hocke, Volker Thiel, Klaus Osterrieder, Thorsten Wolff, Ulrich Martin, Victor M Corman, Marcel A Müller, Christine Goffinet, Christian Drosten
Publikováno v:
PLoS Biology, Vol 20, Iss 11, p e3001871 (2022)
Epidemiological data demonstrate that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) Alpha and Delta are more transmissible, infectious, and pathogenic than previous variants. Phenotypic properties of VOC rema
Externí odkaz:
https://doaj.org/article/f439c20a5aa647faba500c0b3fd9f88a