Zobrazeno 1 - 10
of 215
pro vyhledávání: '"C, Hinrichs"'
Publikováno v:
Biogeosciences, Vol 20, Pp 3717-3735 (2023)
The partitioning of CO2 between atmosphere and ocean depends to a large degree not only on the amount of dissolved inorganic carbon (DIC) but also on alkalinity in the surface ocean. That is also why ocean alkalinity enhancement (OAE) is discussed as
Externí odkaz:
https://doaj.org/article/5283a7273a7c4b18bbdade3f17a036ec
Autor:
Adriana Lori, Brad D. Pearce, Seyma Katrinli, Sierra Carter, Charles F. Gillespie, Bekh Bradley, Aliza P. Wingo, Tanja Jovanovic, Vasiliki Michopoulos, Erica Duncan, Rebecca C. Hinrichs, Alicia Smith, Kerry J. Ressler
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
BackgroundMood disorders such as major depressive and bipolar disorders, along with posttraumatic stress disorder (PTSD), schizophrenia (SCZ), and other psychotic disorders, constitute serious mental illnesses (SMI) and often lead to inpatient psychi
Externí odkaz:
https://doaj.org/article/c52d3c4632094541ae1abe3fc3769a9f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionMucosal-associated invariant T (MAIT) cells might play a role in B cell hyperactivity and local inflammation in primary Sjögren’s syndrome (pSS), just like previously studied mucosa-associated CCR9+ and CXCR5+ T helper cells. Here, we
Externí odkaz:
https://doaj.org/article/8937f8207a854d288f39f6a3bbedfb78
Autor:
Anneline C. Hinrichs, Sofie L. M. Blokland, Aike A. Kruize, Floris P. J. Lafeber, Helen L. Leavis, Joel A. G. van Roon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionIncreased CCL5 expression and CD8 T cells have been shown to be pivotal regulators of immunopathology in primary Sjögren’s syndrome (pSS) and pSS-like disease. Increased CCL5 expression by CCR9+ CD4 T cells has previously been implicat
Externí odkaz:
https://doaj.org/article/72a6a876f5d248908f8f6663bcfcea3a
Autor:
Ana P. Lopes, Cornelis P. J. Bekker, Maarten R. Hillen, Sofie L. M. Blokland, Anneline C. Hinrichs, Aridaman Pandit, Aike A. Kruize, Timothy R. D. J. Radstake, Joel A. G. van Roon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by infiltration of the exocrine glands and prominent B cell hyperactivity. Considering the key role of monocytes in promoting B cell hyperactivity, we performed RNA-se
Externí odkaz:
https://doaj.org/article/a9722ea29bae488390f401c8092783ed
Autor:
Anneline C. Hinrichs, Sofie L. M. Blokland, Ana P. Lopes, Catharina G. K. Wichers, Aike A. Kruize, Aridaman Pandit, Timothy R. D. J. Radstake, Joel A. G. van Roon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionCCR9+ Tfh-like pathogenic T helper (Th) cells are elevated in patients with primary Sjögren’s syndrome (pSS) and indicated to play a role in pSS immunopathology. Here we delineate the CCR9+ Th cell-specific transcriptome to study the m
Externí odkaz:
https://doaj.org/article/2ee682a5fca5423b96e9810c5dd65a8c
Autor:
D. Sidorenko, H.F. Goessling, N.V. Koldunov, P. Scholz, S. Danilov, D. Barbi, W. Cabos, O. Gurses, S. Harig, C. Hinrichs, S. Juricke, G. Lohmann, M. Losch, L. Mu, T. Rackow, N. Rakowsky, D. Sein, T. Semmler, X. Shi, C. Stepanek, J. Streffing, Q. Wang, C. Wekerle, H. Yang, T. Jung
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 11, Iss 11, Pp 3794-3815 (2019)
Abstract A new global climate model setup using FESOM2.0 for the sea ice‐ocean component and ECHAM6.3 for the atmosphere and land surface has been developed. Replacing FESOM1.4 by FESOM2.0 promises a higher efficiency of the new climate setup compa
Externí odkaz:
https://doaj.org/article/788031fb96614560af7484ebb868377d
Autor:
Tiago Carvalheiro, Marzia Rossato, Marta Cossu, Catherina G.K. Wichers, Lorenzo Beretta, Eleni Chouri, Jonas J.W. Kuiper, Femke Bonte-Minheur, Sandra C Silva-Cardoso, Nila H. Servaas, Anneline C Hinrichs, Timothy R D J Radstake, Aridaman Pandit, Nadia Vazirpanah, Alsya J. Affandi, Maarten van der Kroef, Cornelis P. J. Bekker, Andrea Ottria, Marianne Boes, Sanne Hiddingh
Publikováno v:
Arthritis and Rheumatology. John Wiley and Sons Ltd
ObjectivesTo identify key disease pathways driving conventional dendritic cell (cDC) alterations in Systemic Sclerosis (SSc).MethodsTranscriptomic profiling was performed on peripheral blood CD1c+ cDCs (cDC2s) isolated from 12 healthy donors and 48 S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f44e5944c3ffe699cec9a70c44ca8b1
https://doi.org/10.1002/art.42319
https://doi.org/10.1002/art.42319
Autor:
Ana P Lopes, Maarten R Hillen, Anneline C Hinrichs, Sofie LM Blokland, Cornelis PJ Bekker, Aridaman Pandit, Aike A Kruize, Timothy RDJ Radstake, Joel A van Roon
Publikováno v:
Annals of the Rheumatic Diseases. 82:374-383
ObjectiveType 2 conventional dendritic cells (cDC2s) are key orchestrators of inflammatory responses, linking innate and adaptative immunity. Here we explored the regulation of immunological pathways in cDC2s from patients with primary Sjögren’s s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e670d596b7b5668c635bf623e23d803d
https://doi.org/10.1136/ard-2022-222728
https://doi.org/10.1136/ard-2022-222728
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