Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C, Hilf"'
Publikováno v:
PLoS Biology, Vol 14, Iss 3, p e1002393 (2016)
Pentameric ligand-gated ion channels are activated by the binding of agonists to a site distant from the ion conduction path. These membrane proteins consist of distinct ligand-binding and pore domains that interact via an extended interface. Here, w
Externí odkaz:
https://doaj.org/article/6ac09183cdf04c2097f2c0fc18f0c7ce
Publikováno v:
PLoS Biology
PLoS Biology, Vol 14, Iss 3, p e1002393 (2016)
PLoS Biology, Vol 14, Iss 3, p e1002393 (2016)
Pentameric ligand-gated ion channels are activated by the binding of agonists to a site distant from the ion conduction path. These membrane proteins consist of distinct ligand-binding and pore domains that interact via an extended interface. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f177526c72991c5027fde37bbb4c562
http://europepmc.org/articles/PMC4778918
http://europepmc.org/articles/PMC4778918
Autor:
Raimund Dutzler, Ricarda J. C. Hilf
Publikováno v:
Nature. 452:375-379
Pentameric ligand-gated ion channels (pLGICs) are key players in the early events of electrical signal transduction at chemical synapses. The family codes for a structurally conserved scaffold of channel proteins that open in response to the binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2e82dd571d64c88678384009059a16
https://doi.org/10.1038/nature06717
https://doi.org/10.1038/nature06717
Autor:
Volker Huge, A. Beyer, P. Schöps, Shahnaz Christina Azad, Hans-Ulrich Dodt, C. Hilf, Walter Zieglgänsberger, Gerhard Rammes
Publikováno v:
Der Schmerz. 19:521-527
AIM The aim of this study was to evaluate the role of the endogenous cannabinoid system in controlling neuroplasticity. METHODS The pain threshold for electrical stimuli was determined in transgenic mice lacking the cannabinoid receptor type 1 (CB1(-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f147fc9385bf017de3eae1162d97a18
https://doi.org/10.1007/s00482-004-0342-2
https://doi.org/10.1007/s00482-004-0342-2
Autor:
Carlo Bertozzi, Dirk Trauner, Ricarda J. C. Hilf, Alwin Reiter, Iwan Zimmermann, Raimund Dutzler
Publikováno v:
Nature structural & molecular biology
The flow of ions through cation-selective members of the pentameric ligand-gated ion channel family is inhibited by a structurally diverse class of molecules that bind to the transmembrane pore in the open state of the protein. To obtain insight into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e731a9dc90aaad3ed53254247a8a84ec
Autor:
Raimund Dutzler, Ricarda J. C. Hilf
Publikováno v:
Current opinion in structural biology. 19(4)
The X-ray structures of two prokaryotic pentameric ligand-gated ion channels have recently provided detailed insight into this important family of neurotransmitter receptors. These prokaryotic homologs share the overall architecture of their eukaryot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3459432f5a7c9ac428baffd904d7c084
https://pubmed.ncbi.nlm.nih.gov/19646860
https://pubmed.ncbi.nlm.nih.gov/19646860
Autor:
Raimund Dutzler, Ricarda J. C. Hilf
Publikováno v:
Nature; Vol 457
The X-ray structure of a pentameric ligand-gated ion channel from Erwinia chrysanthemi (ELIC) has recently provided structural insight into this family of ion channels at high resolution. The structure shows a homo-pentameric protein with a barrel-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5bf175d354c0950c3266988cd68662
Publikováno v:
Schmerz (Berlin, Germany). 19(6)
The aim of this study was to evaluate the role of the endogenous cannabinoid system in controlling neuroplasticity.The pain threshold for electrical stimuli was determined in transgenic mice lacking the cannabinoid receptor type 1 (CB1(-/-)) and in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f81cefb52e06d9e1f15cd057e39a3f5b
https://pubmed.ncbi.nlm.nih.gov/16328555
https://pubmed.ncbi.nlm.nih.gov/16328555
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Akademický článek
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