Zobrazeno 1 - 10
of 174
pro vyhledávání: '"C, Hession"'
Autor:
Matan Sorek, Walaa Oweis, Malka Nissim-Rafinia, Moria Maman, Shahar Simon, Cynthia C. Hession, Xian Adiconis, Sean K. Simmons, Neville E. Sanjana, Xi Shi, Congyi Lu, Jen Q. Pan, Xiaohong Xu, Mahmoud A. Pouladi, Lisa M. Ellerby, Feng Zhang, Joshua Z. Levin, Eran Meshorer
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-25 (2021)
Abstract Background Many neurodegenerative diseases develop only later in life, when cells in the nervous system lose their structure or function. In many forms of neurodegenerative diseases, this late-onset phenomenon remains largely unexplained. Re
Externí odkaz:
https://doaj.org/article/ef6b9f08c22b4b3bb7ae4a84695c552b
Autor:
Cynthia C. Hession, Walaa Oweis, Lisa M. Ellerby, Mahmoud A. Pouladi, Xiaohong Xu, Malka Nissim-Rafinia, Matan Sorek, Xian Adiconis, Neville E. Sanjana, Congyi Lu, Xi Shi, Moria Maman, Jen Q. Pan, Eran Meshorer, Sean Simmons, Shahar Simon, Joshua Z. Levin, Feng Zhang
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-25 (2021)
Genome Biology
Genome Biology
Background Many neurodegenerative diseases develop only later in life, when cells in the nervous system lose their structure or function. In many forms of neurodegenerative diseases, this late-onset phenomenon remains largely unexplained. Results Ana
Autor:
Tyler Burks, Jiarui Ding, Shaina Carroll, Lan T. Nguyen, Shuqiang Li, Travis K. Hughes, Boaz Barak, Joshua Z. Levin, Alex K. Shalek, William Ge, Xian Adiconis, Nir Hacohen, John Y. Kwon, Sean Simmons, Aviv Regev, Nemanja D. Marjanovic, Cynthia C. Hession, Alexandra-Chloé Villani, Monika S. Kowalczyk, Orit Rozenblatt-Rosen, Marc H. Wadsworth, Amanda J. Kedaigle
Publikováno v:
Nature Biotechnology. 38:737-746
The scale and capabilities of single-cell RNA-sequencing methods have expanded rapidly in recent years, enabling major discoveries and large-scale cell mapping efforts. However, these methods have not been systematically and comprehensively benchmark
Autor:
Brian C. Hession, Carlos M. Duarte, Alan Barozzi, Grégoire Michoud, Francis L. Mallon, Antonio Delgado-Huertas, Daniele Daffonchio, Abdulakader M. Afifi, Anders Røstad, Giuseppe Merlino
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
The previously uncharted Afifi brine pool was discovered in the eastern shelf of the southern Red Sea. It is the shallowest brine basin yet reported in the Red Sea (depth range: 353.0 to 400.5 m). It presents a highly saline (228 g/L), thalassohaline
Autor:
Yinqing Li, Zhanyan Fu, Holger Lerche, Stephen Sanders, Andreas Brunklaus, Xian Adiconis, Joshua Z. Levin, Dennis Lal, Steven A. McCarroll, Miriam H. Meisler, Boaz Barak, Cynthia C. Hession, Reut Shema, Rikke S. Møller, Sean Simmons, Guoping Feng, Juanjiangmeng Du, Arthur J. Campbell
Publikováno v:
Du, J, Simmons, S, Brunklaus, A, Adiconis, X, Hession, C C, Fu, Z, Li, Y, Shema, R, Møller, R S, Barak, B, Feng, G, Meisler, M, Sanders, S, Lerche, H, Campbell, A J, McCarroll, S, Levin, J Z & Lal, D 2020, ' Differential excitatory vs inhibitory SCN expression at single cell level regulates brain sodium channel function in neurodevelopmental disorders ', European Journal of Paediatric Neurology, vol. 24, pp. 129-133 . https://doi.org/10.1016/j.ejpn.2019.12.019
The four voltage-gated sodium channels SCN1/2/3/8A have been associated with heterogeneous types of developmental disorders, each presenting with disease specific temporal and cell type specific gene expression. Using single-cell RNA sequencing trans
Akademický článek
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Autor:
Junying Yuan, Kongyan Niu, Zhirui Hu, Lauren Mifflin, Beth Stevens, Cynthia C. Hession, Jun Liu, Connor Dufort, Nan Liu, Joshua Z. Levin, Alec J. Walker, Hong Zhu, Chengyu Zou
Publikováno v:
Proc Natl Acad Sci U S A
Microglial-derived inflammation has been linked to a broad range of neurodegenerative and neuropsychiatric conditions, including amyotrophic lateral sclerosis (ALS). Using single-cell RNA sequencing, a class of Disease-Associated Microglia (DAMs) hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9db6efe7a8c7513bc8baa3be649e490
https://europepmc.org/articles/PMC8020785/
https://europepmc.org/articles/PMC8020785/
Autor:
Jen Q. Pan, Cynthia C. Hession, Walaa Oweis, Matan Sorek, Xian Adiconis, Malka Nissim-Rafinia, Neville E. Sanjana, Shahar Simon, Moria Maman, Lisa M. Ellerby, Congyi Lu, Joshua Z. Levin, Eran Meshorer, Xi Shi, Sean Simmons, Mahmoud A. Pouladi, Xiaohong Xu, Feng Zhang
BackgroundMany neurodegenerative diseases (NDs) develop only later in life, when cells in the nervous system lose their structure or function. In genetic forms of NDs, this late onset phenomenon remains largely unexplained.ResultsAnalyzing single cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77553adc97990baadc98c9503602ff5b
https://doi.org/10.1101/2020.12.02.398263
https://doi.org/10.1101/2020.12.02.398263
Autor:
Aviv Regev, Orit Rozenblatt-Rosen, Cynthia C. Hession, Travis K. Hughes, Jiarui Ding, Nir Hacohen, Amanda J. Kedaigle, Marc H. Wadsworth, Alex K. Shalek, Sean Simmons, William Ge, Joshua Z. Levin, Lan T. Nguyen, Nemanja D. Marjanovic, Boaz Barak, Tyler Burks, Shaina Carroll, Monika S. Kowalczyk, Shuqiang Li, John Y. Kwon, Alexandra-Chloé Villani, Xian Adiconis
Publikováno v:
Nat Biotechnol
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
John Y. Kwon, Sean Simmons, Tyler Burks, Joshua Z. Levin, Shaina Carroll, Aviv Regev, Jiarui Ding, Monika S. Kowalczyk, Lan T. Nguyen, Alexandra-Chloé Villani, Orit Rozenblatt-Rosen, Boaz Barak, Cynthia C. Hession, Shuqiang Li, Amanda J. Kedaigle, Travis K. Hughes, Xian Adiconis, Marc H. Wadsworth, Alex K. Shalek, William Ge, Nir Hacohen, Nemanja D. Marjanovic
A multitude of single-cell RNA sequencing methods have been developed in recent years, with dramatic advances in scale and power, and enabling major discoveries and large scale cell mapping efforts. However, these methods have not been systematically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34a09c1cf4ed435014e1154d27078bd