Zobrazeno 1 - 10
of 1 553
pro vyhledávání: '"C, Hay"'
Autor:
Eduardo H. Gilglioni, Ao Li, Wadsen St-Pierre-Wijckmans, Tzu-Keng Shen, Israel Pérez-Chávez, Garnik Hovhannisyan, Michela Lisjak, Javier Negueruela, Valerie Vandenbempt, Julia Bauzá-Martinez, Jose M. Herranz, Daria Ezeriņa, Stéphane Demine, Zheng Feng, Thibaut Vignane, Lukas Otero Sanchez, Flavia Lambertucci, Alena Prašnická, Jacques Devière, David C. Hay, Jose A. Encinar, Sumeet Pal Singh, Joris Messens, Milos R. Filipovic, Hayley J. Sharpe, Eric Trépo, Wei Wu, Esteban N. Gurzov
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Fat accumulation, de novo lipogenesis, and glycolysis are key drivers of hepatocyte reprogramming and the consequent metabolic dysfunction-associated steatotic liver disease (MASLD). Here we report that obesity leads to dysregulated expressi
Externí odkaz:
https://doaj.org/article/47d15d12bd9c4154ade149ceeddbddb9
Publikováno v:
Biosensors, Vol 14, Iss 9, p 425 (2024)
Traditional drug development is a long and expensive process with high rates of failure. This has prompted the pharmaceutical industry to seek more efficient drug development frameworks, driving the emergence of organ-on-a-chip (OOC) based on microfl
Externí odkaz:
https://doaj.org/article/75cec231f84a4df882a469a0e36ad3f4
Publikováno v:
Cells, Vol 13, Iss 18, p 1594 (2024)
To accurately study human organ function and disease ‘in the dish’, it is necessary to develop reliable cell-based models that closely track human physiology. Our interest lay with the liver, which is the largest solid organ in the body. The live
Externí odkaz:
https://doaj.org/article/0462fd83545e40cb9ad3d4ac00b00098
Autor:
David C. Hay
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30396- (2024)
Externí odkaz:
https://doaj.org/article/e003d894591640de8e7ba3b5422997d9
Autor:
Melanie C. Hay, Ankit T. Hinsu, Prakash G. Koringa, Ramesh J. Pandit, Po-Yu Liu, Mithil J. Parekh, Subhash J. Jakhesara, Xiaoxai Dai, Matteo Crotta, Bruno Fosso, Georgina Limon, Javier Guitian, Fiona M. Tomley, Dong Xia, Androniki Psifidi, Chaitanya G. Joshi, Damer P. Blake
Publikováno v:
Frontiers in Microbiomes, Vol 2 (2023)
Identifying farming practices that decrease susceptibility to infectious diseases and optimise food conversion efficiency is valuable for chicken welfare and productivity, the environment, and public health. Enterotypes can be used to define microbia
Externí odkaz:
https://doaj.org/article/65ce23c9d4fe43a0804613505e671f1a
Publikováno v:
Cells, Vol 12, Iss 12, p 1604 (2023)
The liver performs a multitude of bodily functions, whilst retaining the ability to regenerate damaged tissue. In this review, we discuss sex steroid biology, regulation of mammalian liver physiology and the development of new model systems to improv
Externí odkaz:
https://doaj.org/article/71480124054547bf98b11a651933734b
Publikováno v:
Disability & Rehabilitation; Aug2024, Vol. 46 Issue 16, p3577-3585, 9p
Autor:
Sohinee Bhattacharya, Edwin Amalraj Raja, David C Hay, Rod Thomas Mitchell, Aikaterini Zafeiri, Paul A Fowler
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Objectives To identify any associations between in utero exposure to five over-the-counter (non-prescription) analgesics (paracetamol, ibuprofen, aspirin, diclofenac, naproxen) and adverse neonatal outcomes.Design Retrospective cohort study using the
Externí odkaz:
https://doaj.org/article/1b635d995f49455dbbcc9efa361a1ba6
Autor:
Abbie C. Hay, Jonathan Sandoval-Castillo, Georgina M. Cooke, Ning L. Chao, Luciano B. Beheregaray
Publikováno v:
Frontiers in Ecology and Evolution, Vol 10 (2022)
Understanding the role of natural selection in the evolution of wild populations is challenging due to the spatial complexity of natural systems. The richest diversity of freshwater fishes in the world is found in the Amazon Basin, a system where mar
Externí odkaz:
https://doaj.org/article/8db36bdc88e247a39849436f8bd99b01
Publikováno v:
The Planetary Science Journal, Vol 4, Iss 2, p 23 (2023)
Several solar system moons harbor subsurface water oceans; extreme internal heating or solar irradiation can form magma oceans in terrestrial bodies. Tidal forces drive ocean currents, producing tidal heating that affects the thermal−orbital evolut
Externí odkaz:
https://doaj.org/article/03e7582d4c64450b9494fa9604ea7bb2