Zobrazeno 1 - 10
of 353
pro vyhledávání: '"C, Guaza"'
Publikováno v:
Neurobiology of Disease, Vol 59, Iss , Pp 141-150 (2013)
Inflammation in the central nervous system (CNS) is a complex process that involves a multitude of molecules and effectors, and it requires the transmigration of blood leukocytes across the blood–brain barrier (BBB) and the activation of resident i
Externí odkaz:
https://doaj.org/article/41e0fc32724248e6bd03babe9b39f8f7
Autor:
F. Loría, S. Petrosino, M. Hernangómez, L. Mestre, A. Spagnolo, F. Correa, V. Di Marzo, F. Docagne, C. Guaza
Publikováno v:
Neurobiology of Disease, Vol 37, Iss 1, Pp 166-176 (2010)
The aim of this study was to evaluate how endocannabinoids interact with excitotoxic processes both in vitro, using primary neural cell cultures, and in vivo, in the TMEV-IDD model of multiple sclerosis. First, we observed that neuronal cells respond
Externí odkaz:
https://doaj.org/article/26689636fb4040f29dab2923dee28832
Autor:
M. Aas, R. Abalo, O.M.E. Abdel-Salam, V.C. Abilio, G.R. Adelli, M.H. Ahmed, M. Alhouayek, J. Allen, D.J. Allsop, R.C. Almada, V. Almeida, A. Aloway, S. Amanullah, S.L. Ames, B. Annaheim, G. Appendino, H. Aramaki, F. Arias-Horcajadas, C. Ariza, J.C. Arnold, D. Asmaro, V. Auwärter, S. Bachmann, A. Baker, R.E. Balter, P.G. Baraldi, P.A. Barber, E. Barbería, G. Bar-Sela, L. Bastiani, D. Basu, I. Basurte, O. Beck, S. Behrendt, D. Bergen-Cico, F. Berrendero, P. Bhagav, S. Bhattacharyya, M. Bioque, S. Bolkent, J.H. Boman, P. Bondallaz, U. Bonnet, R.S. Borges, K. Borowiak, I. Boschi, L.K. Brents, C.H. Bridts, A. Bruno, B.T. Burrows, G.F. Busatto, R.C. Callaghan, A.C. Campos, U.M. Camsari, A. Canfield, E. Carra, F.-J. Carrillo-Salinas, F. Cascini, M.P. Castelli, S.O. Cawich, E.E. Cawston, C. Cedro, M.H.N. Chagas, C. Chen, C. Chisari, H. Chtioui, R.D. Cico, I.A. Ciechomska, N.C. Coimbra, J. Cole, J. Cookey, J. Copeland, Z.M. Coskun, W.D. Crano, J.A.S. Crippa, C.E. Crocker, M.J. Cuesta, P.J. Cunha, L. Cutando, A.B.F. da Silva, J.A. da Silva, V.K. da Silva, D. Dan, R.B. De Boni, F. Rodríguez de Fonseca, R. Gómez de Heras, A.C.P. de Oliveira, A.C. de Souza Crippa, J.A. de Souza Crippa, F. Degenhardt, L. Degenhardt, S. Deiana, U. Deonarine, M. Di Forti, T. dos Anjos-Garcia, R. Guimarães dos Santos, M. Drozd, F.L.S. Duran, M. Earleywine, D.G. Ebo, N. Egashira, J. Egnatios, A. Ellert-Miklaszewska, S.A. ElShebiney, M.A. ElSohly, C. Evren, L. Fañanás, M.M. Faber, S. Farag, A. Farré, M. Farré, M. Fatjó-Vilas, B. Favrat, D. Feingold, A. Feliú, A.A. Fernández, S. Fernández-Artamendi, A.J. Ferrari, L. Ferraro, J. Fichna, D.B. Finlay, J. Fiz, Á. Flores, J.S. Fogel, E. Fornari, L. Fortunato, T. Fyfe, A.E.D.M. Gaafar, S. Gade, E. Gaffal, A.F. Galal, R. Gandhi, P. Gates, J.M. Gatley, C. Giroud, M. Glass, S.R. Goldberg, I. González-Ortega, A. González-Pinto, C. Guaza, V. Guillon, F.S. Guimarães, W. Gul, F.M. Guven, W.D. Hall, J.E.C. Hallak, M. Hamerle, M. Haney, H.E. Harding, S. Hassan, K. Haugland, A. Healey, C. Heck, A. Helander, L. Hernandez-Folgado, D.A. Herzig, M. Hesse, M.G. Hill, R. Hirst, C.R. Hjorthøj, E. Hoch, M.D. Holder, M. Holtkamp, M.R. Hunter, E. Ikeda, Y. Izumi, T. Janus, B. Kaminska, A.S. Kanaan, R. Karinen, T. Karl, T. Katsu, F. Kay-Lambkin, O. Kayser, M. Kells, B.C. Kelly, T.H. Kelly, A. Kokona, A. Kumar, P. Kumar, D. La Barbera, T.V. Lagerberg, A. Lahat, H.J. Larsen, A.S. Laun, T. Lecomte, S. Legleye, S. Lev-Ran, J.A. Lile, R.P. Limberger, I.M.P. Linares, K.M. Lisdahl, M. Little, W. Liu, M.J. Loflin, R. Lorente-Omeñaca, V. Lorenzetti, D. Lu, J. Mørland, K.R. Müller-Vahl, A. Machoy-Mokrzyńska, P. Maeder, S. Majumdar, R. Maldonado, K.E. Maple, T. Marrón, M. Martínez-Cengotitabengoa, M. Isabel Martín-Fontelles, R. Martín-Santos, K. Masuda, A.L. McRae-Clark, M. Mecha, J. Medallo, I. Melle, S. Menahem, J. Mendes-Gomes, B. Mesías, S. Miller, R. Mizrahi, S. Molinaro, C. Moore, M.F. Moraes, F.A. Moreira, L. Moreno-Izco, H.A. Morris, E. Muñoz, G.G. Muccioli, M.R.A. Muscatello, S.A. Nada, V. Naraynsingh, S. Narimatsu, G. Nogueira-Filho, M. Nordentoft, G. Oguz, Å.M.L. Øiestad, E.L. Øiestad, H. Okazaki, M.F. Olive, L. Orio, A. Ozaita, A. Pérez, G. Panagis, G. Pandolfo, L.V. Panlilio, K. Paquin, P. Parakh, L.A. Parker, V.B. Patel, M. Pawson, F.F. Peres, H. Petras, F. Pollastro, A. Porcu, R. Potente, D.E. Potter, S. Potvin, C. Prats, V.R. Preedy, R. Rajendram, L. Rathke, K.L. Reed, M.A. Repka, H. Rigter, E.M. Rock, H. Rohrbacher, P.G.P. Rosa, F. Sánchez-Martínez, A.M. Sánchez-Torres, M. Sałaga, V. Sabato, A.N. Sanders, L.C. Santos, M. Scalese, M.S. Schaufelberger, N. Schröder, G. Scimeca, R. Secades-Villa, D. Selvarajah, O. Senormanci, K. Shivakumar, L.A. Shrier, V. Siciliano, L. Sideli, J.T. Siegel, A.A. Sleem, J. Sobczyński, L. Sodos, N. Solowij, Z.-H. Song, A.W. Stacy, F. Stehle, J.M. Stogner, S. Sussman, W. Swift, N. Szerman, T. Tüting, M. Aghazadeh Tabrizi, O. Taglialatela-Scafati, R.N. Takahashi, S. Takeda, I. Tarricone, D.P. Tashkin, T. Tellioğlu, Z. Tellioğlu, S. Tesfaye, L. Thornton, B. Thylstrup, P.G. Tibbo, G. Todd, M. Torrens, J. Tsai, H.-H. Tseng, A. Turner, S.S. Tuv, F. Ullah, T. Van der Linden, A.L. Van Gasse, P. Vega, G. Vera, M. Verdichevski, T.R. Vieira Sousa, L.R. Vilela, V. Vindenes, Z. Walsh, K. Watanabe, L.R. Watterson, J.M. White, N.E. Wright, M. Yücel, I. Yamamoto, S. Yamaori, A. Zalesky, D. Zalman, J. Zhang, Y. Zhang, R. Zoccali, C.F. Zorumski, A.W. Zuardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59eadc94fe0b85fc20a11a35bf472649
https://doi.org/10.1016/b978-0-12-800756-3.00140-x
https://doi.org/10.1016/b978-0-12-800756-3.00140-x
Akademický článek
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Autor:
A, Feliú, M, Moreno-Martet, M, Mecha, F J, Carrillo-Salinas, E, de Lago, J, Fernández-Ruiz, C, Guaza
Publikováno v:
British journal of pharmacology. 172(14)
Sativex(®) is an oromucosal spray, containing equivalent amounts of Δ(9) -tetrahydrocannabinol (Δ(9) -THC) and cannabidiol (CBD)-botanical drug substance (BDS), which has been approved for the treatment of spasticity and pain associated to multipl
PDE7 inhibitor TC3.6 ameliorates symptomatology in a model of primary progressive multiple sclerosis
Autor:
L, Mestre, M, Redondo, F J, Carrillo-Salinas, J A, Morales-García, S, Alonso-Gil, A, Pérez-Castillo, C, Gil, A, Martínez, C, Guaza
Publikováno v:
British journal of pharmacology. 172(17)
cAMP plays an important role in the transduction of signalling pathways involved in neuroprotection and immune regulation. Control of the levels of this nucleotide by inhibition of cAMP-specific PDEs such as PDE7 may affect the pathological processes
Akademický článek
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Autor:
A, Arévalo-Martín, D, García-Ovejero, O, Gómez, A, Rubio-Araiz, B, Navarro-Galve, C, Guaza, E, Molina-Holgado, F, Molina-Holgado
Publikováno v:
British journal of pharmacology. 153(2)
Amongst the various demyelinating diseases that affect the central nervous system, those induced by an inflammatory response stand out because of their epidemiological relevance. The best known inflammatory-induced demyelinating disease is multiple s
Publikováno v:
Microscopy research and technique. 52(6)
Maturation of oligodendrocyte progenitors (O2A) is characterized by morphological changes and the sequential expression of specific antigens leading to the formation of myelin membrane. Monoclonal antibodies A2B5, A007, anti-vimentin, and anti-galact
Publikováno v:
The European journal of neuroscience. 13(3)
Proinflammatory mediators have been implicated in demyelinating disorders, including multiple sclerosis, whereas it has been proposed that the anti-inflammatory cytokines interleukin- (IL-) 4 and IL-10 participate in disease recovery. The present stu