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of 10
pro vyhledávání: '"C, Goulah"'
Autor:
Michael G. Malkowski, Danielle M. Simmons, Christopher C. Goulah, Mary Koszelak-Rosenblum, Liliana Wroblewski, Adam Krol
Publikováno v:
Journal of Biological Chemistry. 283:24962-24971
Pathogen-inducible oxygenase (PIOX) oxygenates fatty acids into 2R-hydroperoxides. PIOX belongs to the fatty acid α-dioxygenase family, which exhibits homology to cyclooxygenase enzymes (COX-1 and COX-2). Although these enzymes share common catalyti
Autor:
Laurie K. Read, Christopher C. Goulah
Publikováno v:
Journal of Biological Chemistry. 282:7181-7190
Mitochondrial gene expression in Trypanosoma brucei involves the coordination of multiple events including polycistronic transcript cleavage, polyadenylation, RNA stability, and RNA editing. Arg methylation of RNA binding proteins has the potential t
Autor:
Michal K. Stachowiak, Timothy Buckley, Purnendu Dutta, Indrajit Roy, Ewa K. Stachowiak, Haridas E. Pudavar, John Nayda, Thomas D. Corso, German Torres, Earl J. Bergey, Angelo S. Gambino, David C. Bloom, William J. Bowers, Christopher C. Goulah
Publikováno v:
Molecular Brain Research. 139:361-366
The effects of HSV-1 amplicon and polyethyleneimine (PEI)-mediated transfection of dominant negative FGF receptor-1 mutant FGFR1(TK-) into the rat brain substantia nigra (SN) were examined in vivo to model the reduced FGF signaling documented to occu
Publikováno v:
Nucleic Acids Research. 29:5216-5225
RBP16 is a guide RNA (gRNA)-binding protein that was shown through immunoprecipitation experiments to interact with approximately 30% of total gRNAs in Trypanosoma brucei mitochondria. To gain insight into the biochemical function of RBP16, we used a
Elevated (4 to 7-fold) levels of urinary dolichol and coenzyme Q and substantially longer chain lengths for urinary dolichols have been reported in Smith-Lemli-Opitz Syndrome (SLOS) patients, compared to normal subjects. We investigated the possibili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321342edbe80179fa2e34a4dca50df3f
https://europepmc.org/articles/PMC3595616/
https://europepmc.org/articles/PMC3595616/
Arginine methylation is a post-translational modification that impacts gene expression in both the cytoplasm and nucleus. Here, we demonstrate that arginine methylation also affects mitochondrial gene expression in the protozoan parasite, Trypanosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e201d01482ae86d122b36d0aa7751c16
https://europepmc.org/articles/PMC1524885/
https://europepmc.org/articles/PMC1524885/
Autor:
S, Tabbaa, C, Goulah, R K, Tran, A, Lis, R, Korody, B, Stachowski, J M, Horowitz, G, Torres, E K, Stachowiak, D C, Bloom, M K, Stachowiak
Publikováno v:
Folia morphologica. 59(4)
Manipulation of gene expression in developing or in mature central nervous systems (CNS) holds a promise for the resolution of many compelling neurobiological questions, including the feasibility of gene therapy to treat diseases of the brain. In thi
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