Mechanism of plasma electrolytic oxidation in Mg3ZnCa implants: a study of double-layer formation and properties through nanoindentation

Autor: S. Lashkarara, A. fazlali, K. Ghaseminezhad, C. Fleck, M. Salavati

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Abstract Plasma electrolytic oxidation (PEO), applied to light metals such as titanium, aluminum, and magnesium, creates a two-layer coating and has become increasingly important in metal coatings. However, due to the high voltage and temperature of

Externí odkaz: https://doaj.org/article/ecbdc1e4365846d68cb933adaddd9fff

Nanofatigue behaviour of single struts of cast A356.0 foam: cyclic deformation, nanoindent characteristics and sub-surface microstructure

Autor: M. Schmahl, A. Märten, P. Zaslansky, C. Fleck

Publikováno v: Materials & Design, Vol 195, Iss , Pp 109016- (2020)

Struts are the main load carrying elements in cyclically loaded open cell metal foams. Little is known about the local fatigue behaviour and the influence of the microstructure on nanoscale deformation mechanisms. Different to the bulk counterpart, t

Externí odkaz: https://doaj.org/article/61da763318a24c6bab4e3e7cd7a04a7c

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Safety and efficacy of low-dose PI3K inhibitor taselisib in adult patients with CLOVES and Klippel–Trenaunay syndrome (KTS): the TOTEM trial, a phase 1/2 multicenter, open-label, single-arm study

Autor: Marc Bardou, Pierre Vabres, Laurence Faivre, Annabel Maruani, Victoria E R Parker, A. Phan, Christine Chiaverini, L. Martin, Jill Clayton-Smith, C. Fleck, Maxime Luu, Tristan Mirault, Fanny Morice-Picard, M. Carpentier, Marie-Line Jacquemont, Hervé Devilliers, Marjolaine Willems, A. Maurer, Romaric Loffroy, Didier Bessis, Florence Petit, Robert K. Semple, M. Yousfi

Publikováno v: Genetics in Medicine
Genetics in Medicine, Nature Publishing Group, 2021, ⟨10.1038/s41436-021-01290-y⟩
Luu, M, Vabres, P, Devilliers, H, Loffroy, R, Phan, A, Martin, L, Morice-Picard, F, Petit, F, Willems, M, Bessis, D, Jacquemont, M-L, Maruani, A, Chiaverini, C, Mirault, T, Clayton-Smith, J, Carpentier, M, Fleck, C, Maurer, A, Yousfi, M, Parker, V E R, Semple, R K, Bardou, M & Faivre, L 2021, ' Safety and efficacy of low-dose PI3K inhibitor taselisib in adult patients with CLOVES and KLIPPEL TRENAUNAY SYNDROME (KTS): the TOTEM trial, a phase 1/2 multicentre, open-label, single-arm study ', Genetics in Medicine . https://doi.org/10.1038/s41436-021-01290-y

International audience; ABSTRACT Purpose PIK3CA pathogenic variants in the PIK3CA-related overgrowth spectrum (PROS) activate phosphoinositide 3-kinase signaling, providing a rationale for targeted therapy, but no drug has proven efficacy and safety

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb35a651c9d3e22a4c1a05d557c9a14
https://doi.org/10.1038/s41436-021-01290-y

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