Zobrazeno 1 - 10
of 1 571
pro vyhledávání: '"C, Drummond"'
Autor:
Jonathan B. Sellon, Kathy S. So, Andrew D'Arcangelo, Sarah Cancelarich, Meghan C. Drummond, Peter G. Slade, Ning Pan, Tyler M. Gibson, Tian Yang, Joseph C. Burns, Adam T. Palermo, Lars Becker
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Deafness-causing deficiencies in otoferlin (OTOF) have been addressed preclinically using dual adeno-associated virus (AAV)-based approaches. However, timing of transduction, recombination of mRNA, and protein expression with dual hybrid AAV methods
Externí odkaz:
https://doaj.org/article/a844378fd26b47b3b6c0c1450c88a3a4
Autor:
Rhianna C. Drummond-Clarke
Publikováno v:
Communicative & Integrative Biology, Vol 16, Iss 1 (2023)
ABSTRACTHypotheses have historically linked the emergence and evolution of defining human characteristics such as bipedal walking to ground-dwelling, envisioning our earliest ancestors as living in treeless savannahs (i.e. the traditional savannah hy
Externí odkaz:
https://doaj.org/article/491d1dd8cb66477991e4c188c83ac0ad
Autor:
Kavita Praveen, Lee Dobbyn, Lauren Gurski, Ariane H. Ayer, Jeffrey Staples, Shawn Mishra, Yu Bai, Alexandra Kaufman, Arden Moscati, Christian Benner, Esteban Chen, Siying Chen, Alexander Popov, Janell Smith, GHS-REGN DiscovEHR collaboration, Regeneron Genetics Center, Decibel-REGN collaboration, Olle Melander, Marcus B. Jones, Jonathan Marchini, Suganthi Balasubramanian, Brian Zambrowicz, Meghan C. Drummond, Aris Baras, Goncalo R. Abecasis, Manuel A. Ferreira, Eli A. Stahl, Giovanni Coppola
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
A GWAS and exome-wide association study meta-analysis identifies 53 loci affecting hearing loss risk from over half a million individuals across five cohorts. Rare variants in Mendelian hearing loss genes contribute to hearing loss risk in adults.
Externí odkaz:
https://doaj.org/article/c155a1e114c54095aa702bbcf6d62816
Autor:
B. Bigio, R. Lima-Filho, O. Barnhill, F. Sudo, C. Drummond, N. Assunção, B. Vanderborght, F. Tovar-Moll, P. Mattos, S. Ferreira, F. De Felice, M. Lourenco, C. Nasca
Publikováno v:
European Psychiatry, Vol 66, Pp S611-S611 (2023)
Introduction Prior mechanistic studies in rodents showed decreased levels of the pivotal mitochondrial metabolite acetyl-L-carnitine (LAC) in relation to cognitive deficits and depressive-like behavior (Neuron 2017, 10.1016/j.neuron.2017.09.020, PNAS
Externí odkaz:
https://doaj.org/article/43470aba568e4764930c429ea80b2279
Autor:
Melissa L. Geddie, Dmitri B. Kirpotin, Neeraj Kohli, Tad Kornaga, Bjoern Boll, Maja Razlog, Daryl C. Drummond, Alexey A. Lugovskoy
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Antibody-directed nanotherapeutics (ADNs) represent a promising delivery platform for selective delivery of an encapsulated drug payload to the site of disease that improves the therapeutic index. Although both single-chain Fv (scFv) and Fab antibody
Externí odkaz:
https://doaj.org/article/9d2891dc79f643129c3b3b205c1860ca
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-16 (2021)
Abstract Background COVID-19 continues to represent the single biggest challenge to contemporary community sport globally. Compliance with social distancing policies, strict return-to-play protocols, and COVID-19 specific training has, perhaps, forev
Externí odkaz:
https://doaj.org/article/5ecc38c66dda4aa0807473f62acee432
Autor:
R. Blackwood, A. Wolstenholme, A. Kimergård, S. Fincham-Campbell, Z. Khadjesari, S. Coulton, S. Byford, P. Deluca, S. Jennings, E. Currell, J. Dunne, J. O’Toole, J. Winnington, E. Finch, C. Drummond
Publikováno v:
BMC Public Health, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Alcohol-related hospital admissions have doubled in the last ten years to > 1.2 m per year in England. High-need, high-cost (HNHC) alcohol-related frequent attenders (ARFA) are a relatively small subgroup of patients, having multi
Externí odkaz:
https://doaj.org/article/0b680138614a4531b2e50b3855b06b0d
Publikováno v:
AKCE International Journal of Graphs and Combinatorics, Vol 17, Iss 2, Pp 638-640 (2020)
In this article, we provide an overview of Lowell Beineke’s amazing career at Purdue University Fort Wayne as seen and evaluated throughout the years. An outstanding teacher and researcher, Lowell has left a lasting impact in the careers of many co
Externí odkaz:
https://doaj.org/article/6dcc01f087d74d1c86a38e5eb4eee776
Autor:
Dmitri B. Kirpotin, Mark E. Hayes, Charles O. Noble, Zhaohua Richard Huang, Kshitija Wani, Doug Moore, Kevin Kesper, Drew O’ Brien, Daryl C. Drummond
Publikováno v:
Journal of Pharmaceutical Sciences. 112:416-434
Therapeutics at or close to the nanoscale, such as liposomal irinotecan, offer significant promise for the treatment of solid tumors. Their potential advantage over the unencapsulated or free form of the drug is due in part to their altered biodistri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59bd9f760d124dc003eb2aa686d5244c
https://doi.org/10.1016/j.xphs.2022.11.025
https://doi.org/10.1016/j.xphs.2022.11.025
Publikováno v:
Journal of Internet Services and Applications, Vol 9, Iss 1, Pp 1-18 (2018)
Abstract IP lookup is a core operation in packet forwarding, which is implemented using a Longest Prefix Matching (LPM) algorithm to find the next hop for an input address. This work proposes and evaluates the use of parallel processors to deploy an
Externí odkaz:
https://doaj.org/article/05242854ea0b49b78ba62c1ca65e80dc