Zobrazeno 1 - 10
of 508
pro vyhledávání: '"C, Dorman"'
Autor:
Guillermo Najarro, Kevin Brackett, Hunter Woosley, Leah C Dorman, Vincent Turon-Lagot, Sudip Khadka, Catya Faeldonea, Osvaldo Kevin Moreno, Adriana Ramirez Negron, Christina Love, Ryan Ward, Charles Langelier, Frank McCarthy, Carlos Gonzalez, Joshua E Elias, Brooke M Gardner, Carolina Arias
Publikováno v:
PLoS Pathogens, Vol 20, Iss 10, p e1012660 (2024)
The Endoplasmic Reticulum (ER)-resident HSP70 chaperone BiP (HSPA5) plays a crucial role in maintaining and restoring protein folding homeostasis in the ER. BiP's function is often dysregulated in cancer and virus-infected cells, conferring pro-oncog
Externí odkaz:
https://doaj.org/article/ba9d798e7041468bbfff37dc0d7d585d
Autor:
Lutz Goehring, David C. Dorman, Klaus Osterrieder, Brandy A. Burgess, Kelsie Dougherty, Peggy Gross, Claire Neinast, Nicola Pusterla, Gisela Soboll‐Hussey, David P. Lunn
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1892-1905 (2024)
Abstract Background Equine herpes virus type 1 (EHV‐1) infection in horses is associated with upper respiratory disease, neurological disease, abortions, and neonatal death. Review Question Does pharmacological therapy decrease either the incidence
Externí odkaz:
https://doaj.org/article/08e7211b0dc7489288e1a98f00da1a73
Autor:
Klaus Osterrieder, David C. Dorman, Brandy A. Burgess, Lutz S. Goehring, Peggy Gross, Claire Neinast, Nicola Pusterla, Gisela Soboll Hussey, David P. Lunn
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1858-1871 (2024)
Abstract Background Equine herpes virus type 1 (EHV‐1) infection in horses is associated with respiratory and neurologic disease, abortion, and neonatal death. Hypothesis Vaccines decrease the occurrence of clinical disease in EHV‐1‐infected ho
Externí odkaz:
https://doaj.org/article/8f3a9737b7ba403a9c4fd22ffb30b355
Autor:
David P. Lunn, Brandy A Burgess, David C. Dorman, Lutz S. Goehring, Peggy Gross, Klaus Osterrieder, Nicola Pusterla, Gisela Soboll Hussey
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1290-1299 (2024)
Abstract Equine herpesvirus‐1 (EHV‐1) is a highly prevalent and frequently pathogenic infection of equids. The most serious clinical consequences of infection are abortion and equine herpesvirus myeloencephalopathy (EHM). The previous consensus s
Externí odkaz:
https://doaj.org/article/ca999b68f1b343aca245168ad61dc116
Autor:
Gisela Soboll‐Hussey, David C. Dorman, Brandy A. Burgess, Lutz Goehring, Peggy Gross, Claire Neinast, Klaus Osterrieder, Nicola Pusterla, David P. Lunn
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1872-1891 (2024)
Abstract Background Equine herpes virus type 1 (EHV‐1) infection in horses is associated with upper respiratory disease, neurological disease, abortions, and neonatal death. Objective To determine if there is an association between the level and du
Externí odkaz:
https://doaj.org/article/d7b584cb5dd94c688ec30b23e1710352
Autor:
Nicola Pusterla, David C. Dorman, Brandy A. Burgess, Lutz Goehring, Margaret Gross, Klaus Osterrieder, Gisela Soboll Hussey, David P. Lunn
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1765-1791 (2024)
Abstract Background Equine herpesvirus type 1 (EHV‐1) infection is associated with upper respiratory disease, EHM, abortions, and neonatal death. Research Questions Are nasal secretions a more sensitive biological sample compared to blood for the d
Externí odkaz:
https://doaj.org/article/f338a1e674014e3c9eea8a6798d389e5
Autor:
Elvira Mennillo, Yang Joon Kim, Gyehyun Lee, Iulia Rusu, Ravi K. Patel, Leah C. Dorman, Emily Flynn, Stephanie Li, Jared L. Bain, Christopher Andersen, Arjun Rao, Stanley Tamaki, Jessica Tsui, Alan Shen, Madison L. Lotstein, Maha Rahim, Mohammad Naser, Faviola Bernard-Vazquez, Walter Eckalbar, Soo-jin Cho, Kendall Beck, Najwa El-Nachef, Sara Lewin, Daniel R. Selvig, Jonathan P. Terdiman, Uma Mahadevan, David Y. Oh, Gabriela K. Fragiadakis, Angela Pisco, Alexis J. Combes, Michael G. Kattah
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Ulcerative colitis (UC) is driven by immune and stromal subsets, culminating in epithelial injury. Vedolizumab (VDZ) is an anti-integrin antibody that is effective for treating UC. VDZ is known to inhibit lymphocyte trafficking to the intest
Externí odkaz:
https://doaj.org/article/0ea20593138a4ffda5f1bf392dc9a45e
Publikováno v:
Animals, Vol 14, Iss 23, p 3445 (2024)
Many domesticated dogs show signs of anxiety, negatively impacting their own and their owner’s mental and physical health. A systematic review evaluating whether pressure wraps decrease clinical signs of anxiety in dogs was completed to identify re
Externí odkaz:
https://doaj.org/article/d33fab11b617439a80547659c7d1bc2e
Autor:
Pauli Seppänen, Markus M. Forsberg, Miia Tiihonen, Heikki Laitinen, Selena Beal, David C. Dorman
Publikováno v:
Parkinson's Disease, Vol 2024 (2024)
Background. Rasagiline or pramipexole monotherapy has been suggested for the management of early Parkinson’s disease (PD). The aim of this research was to systematically review the clinical efficacy and safety of rasagiline or pramipexole in early
Externí odkaz:
https://doaj.org/article/32799b2e5bf94a3e90641a0d1592292e
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Microglia remodel synapses and engulf apoptotic cells. The molecular program underlying these distinct functions are unclear. Here, the authors identify distinct microglial subsets associated with synaptic vs. neurogenic regions of the developing zeb
Externí odkaz:
https://doaj.org/article/827e8387a61f43bfa0b99a363397af48