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Publikováno v:
The EMBO Journal. 12:1713-1721
Wild-type human transferrin receptor (hTfR), like endogenous canine receptor, is expressed almost exclusively (97%) at the basolateral membrane of transfected Madin-Darbey canine kidney (MDCK) cells. We investigated the role of two distinct features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa8b8ed9217a7f2f90232403ecf1079
https://doi.org/10.1002/j.1460-2075.1993.tb05816.x
https://doi.org/10.1002/j.1460-2075.1993.tb05816.x
Autor:
L C Kühn, C Dargemont
Publikováno v:
The Journal of Cell Biology
Export of mRNA from the nucleus to the cytoplasm was studied in mature Xenopus laevis oocytes. In vitro transcribed, capped 32P-labeled mRNA was microinjected into nuclei, and its appearance in the cytoplasm measured by counting radioactivity or by R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0e624d7a6d61973ef2cdd9f5828c16
https://doi.org/10.1083/jcb.118.1.1
https://doi.org/10.1083/jcb.118.1.1
Autor:
Lionel Larue, Elena Caretti, F. Van Roy, C. Dargemont, L. Nelles, Alfonso Bellacosa, J. Bonaventure, A García de Herreros, Isabel Puig, S. Julien
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2007, 26 (53), pp.7445-56. ⟨10.1038/sj.onc.1210546⟩
Oncogene, Nature Publishing Group, 2007, 26 (53), pp.7445-56. ⟨10.1038/sj.onc.1210546⟩
International audience; Carcinoma progression is associated with the loss of epithelial features, and the acquisition of mesenchymal characteristics and invasive properties by tumour cells. The loss of cell-cell contacts may be the first step of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23489da6d8afbf91e474fc75128a4ef3
https://hal.archives-ouvertes.fr/hal-00235814
https://hal.archives-ouvertes.fr/hal-00235814
Publikováno v:
Traffic (Copenhagen, Denmark). 4(8)
The nuclear transport of both proteins and RNAs has attracted considerable interest in recent years. However, regulation pathways of the nuclear transport machineries are still not well characterized. Previous studies indicated that ubiquitination is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bba1e3c6365d38a267a8f3619b3fccb
https://pubmed.ncbi.nlm.nih.gov/12839499
https://pubmed.ncbi.nlm.nih.gov/12839499
Publikováno v:
Traffic (Copenhagen, Denmark). 2(10)
The evolution of the nucleus imposed on eukaryotic cells the necessity to strictly control exchange of molecules between the nucleus and the remainder of the cell, not only to protect and correctly transmit genetic information, but also to coordinate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea70ab390153b891cd8adc20df176a25
https://pubmed.ncbi.nlm.nih.gov/11576444
https://pubmed.ncbi.nlm.nih.gov/11576444
Publikováno v:
The Journal of biological chemistry. 276(28)
Determining the cis-acting elements controlling nuclear export of RNA is critical, because they specify which RNA will be selected for transport. We have characterized the nuclear export motif of the adenoviral VA1 RNA, a small cytoplasmic RNA transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c855c93ca20dae262a3f901d5f682c2
https://pubmed.ncbi.nlm.nih.gov/11342536
https://pubmed.ncbi.nlm.nih.gov/11342536
Publikováno v:
Molecular and cellular biology. 21(10)
Transcriptional activation of NF-kappaB is mediated by signal-induced phosphorylation and degradation of its inhibitor, IkappaBalpha. NF-kappaB activation induces a rapid resynthesis of IkappaBalpha which is responsible for postinduction repression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::702283832786485975d6732707c6a619
https://pubmed.ncbi.nlm.nih.gov/11313474
https://pubmed.ncbi.nlm.nih.gov/11313474
Publikováno v:
The Journal of biological chemistry. 275(46)
IkappaBalpha inhibits the transcriptional activity of NF-kappaB both in the cytoplasm by preventing the nuclear translocation of NF-kappaB and in the nucleus where it dissociates NF-kappaB from DNA and transports it back to the cytoplasm. Cytoplasmic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0dcd2025c86835004439432c07400231
https://pubmed.ncbi.nlm.nih.gov/10969074
https://pubmed.ncbi.nlm.nih.gov/10969074
Publikováno v:
The Journal of biological chemistry. 274(10)
IkappaBalpha controls the transcriptional activity of nuclear factor (NF)-kappaB by retaining it in the cytoplasm; but, when expressed in the nucleus, it can also inhibit the interaction of NF-kappaB with DNA and promote the export of NF-kappaB from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::938059f4e448aeb897b44fbee95a5244
https://pubmed.ncbi.nlm.nih.gov/10037782
https://pubmed.ncbi.nlm.nih.gov/10037782