Zobrazeno 1 - 10
of 1 419
pro vyhledávání: '"C, Clifford"'
Autor:
David R. Ghasemi, Konstantin Okonechnikov, Anne Rademacher, Stephan Tirier, Kendra K. Maass, Hanna Schumacher, Piyush Joshi, Maxwell P. Gold, Julia Sundheimer, Britta Statz, Ahmet S. Rifaioglu, Katharina Bauer, Sabrina Schumacher, Michele Bortolomeazzi, Felice Giangaspero, Kati J. Ernst, Steven C. Clifford, Julio Saez-Rodriguez, David T. W. Jones, Daisuke Kawauchi, Ernest Fraenkel, Jan-Philipp Mallm, Karsten Rippe, Andrey Korshunov, Stefan M. Pfister, Kristian W. Pajtler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Medulloblastomas with extensive nodularity are cerebellar tumors characterized by two distinct compartments and variable disease progression. The mechanisms governing the balance between proliferation and differentiation in MBEN remain poorl
Externí odkaz:
https://doaj.org/article/73c7a67e39074505ad2f97eb63756762
Autor:
David R. Ghasemi, Konstantin Okonechnikov, Anne Rademacher, Stephan Tirier, Kendra K. Maass, Hanna Schumacher, Piyush Joshi, Maxwell P. Gold, Julia Sundheimer, Britta Statz, Ahmet S. Rifaioglu, Katharina Bauer, Sabrina Schumacher, Michele Bortolomeazzi, Felice Giangaspero, Kati J. Ernst, Steven C. Clifford, Julio Saez-Rodriguez, David T. W. Jones, Daisuke Kawauchi, Ernest Fraenkel, Jan-Philipp Mallm, Karsten Rippe, Andrey Korshunov, Stefan M. Pfister, Kristian W. Pajtler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/47da4125f4844105ae9c15e274201e59
Autor:
Henrik Pedersen, Tatiana Skliarova, C. Clifford Attkisson, Mariela L. Lara-Cabrera, Audun Havnen
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Introduction Patient satisfaction with mental health services has for several decades been considered an important component when evaluating service quality. It is often assessed in the context of monitoring quality of care, developing or ev
Externí odkaz:
https://doaj.org/article/7a4bc70300334f50b3c200ff915e0a66
Autor:
Kathryn M. Sturge, Noah Hoppis, Aneesh Anandanatarajan, Ariana M. Bussio, Bryson C. Clifford, Emily H. Frashure, Miriam E. Hiebert, James E. Krutzler, Timothy W. Koeth
Publikováno v:
APL Materials, Vol 12, Iss 3, Pp 031119-031119-6 (2024)
Dielectric charging aboard spacecraft and satellites is a persistent and pressing issue in materials design and applications. This study investigated the effect of electron irradiation on charge trapping and leakage properties in polymethyl methacryl
Externí odkaz:
https://doaj.org/article/698b00da012d428cb1740669064383ff
Autor:
Claire Keeling, Simon Davies, Jack Goddard, Vijay Ramaswamy, Edward C. Schwalbe, Simon Bailey, Debbie Hicks, Steven C. Clifford
Publikováno v:
EClinicalMedicine, Vol 69, Iss , Pp 102469- (2024)
Summary: Background: Medulloblastoma patients with a sub-total surgical resection (STR; >1.5 cm2 primary tumour residuum post-surgery) typically receive intensified treatment. However, the association of STR with poor outcomes has not been observed c
Externí odkaz:
https://doaj.org/article/8aac62da82144c32925d2195f0158088
Autor:
Sarah Kohe, Christopher Bennett, Florence Burté, Magretta Adiamah, Heather Rose, Lara Worthington, Fatma Scerif, Lesley MacPherson, Simrandip Gill, Debbie Hicks, Edward C. Schwalbe, Stephen Crosier, Lisa Storer, Ambarasu Lourdusamy, Dipyan Mitra, Paul S. Morgan, Robert A. Dineen, Shivaram Avula, Barry Pizer, Martin Wilson, Nigel Davies, Daniel Tennant, Simon Bailey, Daniel Williamson, Theodoros N. Arvanitis, Richard G. Grundy, Steven C. Clifford, Andrew C. Peet
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104958- (2024)
Summary: Background: The malignant childhood brain tumour, medulloblastoma, is classified clinically into molecular groups which guide therapy. DNA-methylation profiling is the current classification ‘gold-standard’, typically delivered 3–4 wee
Externí odkaz:
https://doaj.org/article/7ea57b301d434c53922cf4908ce48606
Autor:
Oliver J. Mainwaring, Holger Weishaupt, Miao Zhao, Gabriela Rosén, Anna Borgenvik, Laura Breinschmid, Annemieke D. Verbaan, Stacey Richardson, Dean Thompson, Steven C. Clifford, Rebecca M. Hill, Karl Annusver, Anders Sundström, Karl O. Holmberg, Maria Kasper, Sonja Hutter, Fredrik J. Swartling
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
CDKN2A loss and p53 mutations are rare in MYC-driven Group 3 medulloblastomas (MBs). Here the authors generated a transgenic mouse model of Group 3 MB by MYC overexpression and show that MYC suppresses ARF to drive tumorigenesis.
Externí odkaz:
https://doaj.org/article/15ce094130ad4d1185c37a3fd0a60446
Autor:
Franziska Linke, James E. C. Johnson, Stefanie Kern, Christopher D. Bennett, Anbarasu Lourdusamy, Daniel Lea, Steven C. Clifford, Catherine L. R. Merry, Snow Stolnik, Morgan R. Alexander, Andrew C. Peet, David J. Scurr, Rian L. Griffiths, Anna M. Grabowska, Ian D. Kerr, Beth Coyle
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-18 (2023)
Abstract The most common malignant brain tumour in children, medulloblastoma (MB), is subdivided into four clinically relevant molecular subgroups, although targeted therapy options informed by understanding of different cellular features are lacking
Externí odkaz:
https://doaj.org/article/8e0594bb9b0f4ee79da8bd0f140e5dd2
Autor:
Henrik Pedersen, Audun Havnen, Martin Brattmyr, C. Clifford Attkisson, Mariela L. Lara-Cabrera
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Validated measures of patient-reported experiences are essential for assessing and improving the quality of mental health services and interventions. In Norwegian mental healthcare settings, the Client Satisfaction Questionnaire (
Externí odkaz:
https://doaj.org/article/5e9ef136e3bf4ffcbcc060f89f46dad5