Zobrazeno 1 - 10
of 2 666
pro vyhledávání: '"C, Christensen"'
Autor:
Ze Zhang, Kartik Sehgal, Keisuke Shirai, Rondi A. Butler, John K. Wiencke, Devin C. Koestler, Geat Ramush, Min Kyung Lee, Annette M. Molinaro, Hannah G. Stolrow, Ariel Birnbaum, Lucas A. Salas, Robert I. Haddad, Karl T. Kelsey, Brock C. Christensen
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract Tissue biomarkers for immune checkpoint inhibitor (ICI) response are limited by tumor sample heterogeneity and availability. This study identifies clinically actionable pretreatment blood biomarkers that are associated with ICI treatment res
Externí odkaz:
https://doaj.org/article/fdd69c008307400fa3cabca4cbe4d4c4
Autor:
Natascha H Bohnstedt-Pedersen, Gitte Linderoth, Barbara Helios, Helle C Christensen, Britta K Thomsen, Lisbeth Bekker, Jannie K B Gram, Ulla Vaeggemose, Tine B Gehrt
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Telehealth has become increasingly essential in healthcare provision, also in the Prehospital Emergency Medical Services (EMS), where live video is implemented as a supplemental tool to assess and triage medical emergency calls. S
Externí odkaz:
https://doaj.org/article/2a9d22ed3fa44381b10011b82bbca1e1
Autor:
Steven C. Pike, John K. Wiencke, Ze Zhang, Annette M. Molinaro, Helen M. Hansen, Devin C. Koestler, Brock C. Christensen, Karl T. Kelsey, Lucas A. Salas
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract A scalable platform for cell typing in the glioma microenvironment can improve tumor subtyping and immune landscape detection as successful immunotherapy strategies continue to be sought and evaluated. DNA methylation (DNAm) biomarkers for m
Externí odkaz:
https://doaj.org/article/c2f50a1e2f134257a5b02c38f46d2ea6
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
DNA methylation has been extensively utilized to study epigenetic patterns across many diseases as well as to deconvolve blood cell type proportions. This study builds upon previous studies examining methylation patterns in paediatric patients with v
Externí odkaz:
https://doaj.org/article/64a42ab9c7754acd8d99e08ff9999d68
Autor:
Min Kyung Lee, Nasim Azizgolshani, Joshua A. Shapiro, Lananh N. Nguyen, Fred W. Kolling, George J. Zanazzi, Hildreth Robert Frost, Brock C. Christensen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Central nervous system (CNS) tumors are the leading cause of pediatric cancer death, and these patients have an increased risk for developing secondary neoplasms. Due to the low prevalence of pediatric CNS tumors, major advances in targeted
Externí odkaz:
https://doaj.org/article/0e78f5f944ac4d33a304ccca7e04c5a9
Autor:
Min Kyung Lee, Nasim Azizgolshani, Ze Zhang, Laurent Perreard, Fred W. Kolling, Lananh N. Nguyen, George J. Zanazzi, Lucas A. Salas, Brock C. Christensen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Although intratumoral heterogeneity has been established in pediatric central nervous system tumors, epigenomic alterations at the cell type level have largely remained unresolved. To identify cell type-specific alterations to cytosine modif
Externí odkaz:
https://doaj.org/article/0f056dd83a1c4f31861e1c0484d38c51
Autor:
Madeline E. Olufsen, MD, Jens Hannibal, MD, Nina B. Soerensen, MD, Anders T. Christiansen, MD, Ulrik C. Christensen, MD, Grazia Pertile, MD, David H. Steel, MD, Steffen Heegaard, MD, Jens F. Kiilgaard, MD
Publikováno v:
Ophthalmology Science, Vol 5, Iss 2, Pp 100644- (2025)
Purpose: Autologous retinal transplantation has been successfully employed in the treatment of large and myopic macular holes that are refractory to standard surgical treatments. Patients transplanted with a peripheral neurosensory retinal graft have
Externí odkaz:
https://doaj.org/article/944489fab4b049e5b8b1df74867b7937
Autor:
Niklas Breindahl, Signe A. Wolthers, Thea P. Møller, Stig N. F. Blomberg, Jacob Steinmetz, Helle C. Christensen, the Danish Drowning Validation Group
Publikováno v:
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 32, Iss 1, Pp 1-11 (2024)
Abstract Background Improving oxygenation and ventilation in drowning patients early in the field is critical and may be lifesaving. The critical care interventions performed by physicians in drowning management are poorly described. The aim was to d
Externí odkaz:
https://doaj.org/article/45d372b8f0074a0d95408fff0b991fc4
Autor:
Joshua J Levy, Matthew J Davis, Rachael S Chacko, Michael J Davis, Lucy J Fu, Tarushii Goel, Akash Pamal, Irfan Nafi, Abhinav Angirekula, Anish Suvarna, Ram Vempati, Brock C Christensen, Matthew S Hayden, Louis J Vaickus, Matthew R LeBoeuf
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-18 (2024)
Abstract Successful treatment of solid cancers relies on complete surgical excision of the tumor either for definitive treatment or before adjuvant therapy. Intraoperative and postoperative radial sectioning, the most common form of margin assessment
Externí odkaz:
https://doaj.org/article/570c1948b6fb48e796a4dd6a1535e5e9
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Among men, prostate cancer (PCa) is the second most common cancer and the second leading cause of cancer death. Etiologic factors associated with both prostate carcinogenesis and somatic alterations in tumors are incompletely unde
Externí odkaz:
https://doaj.org/article/2f55d7e66f2e476f80b4ae2313318851