Zobrazeno 1 - 10
of 40
pro vyhledávání: '"C, Chavany"'
Publikováno v:
Methods in molecular medicine. 1
In the laboratory, antisense oligodeoxynucleotides (ODN) have repeatedly demonstrated efficacy in modulating the expression of various genes, thus providing important insights into their roles in tumorigenesis or normal growth and development (1-3).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::829337f225e6fd31fd4140cb61dd056b
https://pubmed.ncbi.nlm.nih.gov/21359716
https://pubmed.ncbi.nlm.nih.gov/21359716
Autor:
C, Chavany, E, Mimnaugh, P, Miller, R, Bitton, P, Nguyen, J, Trepel, L, Whitesell, R, Schnur, J, Moyer, L, Neckers
Publikováno v:
The Journal of biological chemistry. 271(9)
Treatment of SKBr3 cells with benzoquinone ansamycins, such as geldanamycin (GA), depletes p185erbB2, the receptor tyrosine kinase encoded by the erbB2 gene. In the same cells, a biologically active benzoquinone photoaffinity label specifically binds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::576affcc1168fa350af2c189828230d9
https://pubmed.ncbi.nlm.nih.gov/8617772
https://pubmed.ncbi.nlm.nih.gov/8617772
Publikováno v:
Molecular pharmacology. 48(4)
c-myc is overexpressed in glioblastoma multiforme, the most common form of brain tumor. To find a suitable target for in vivo antisense therapy of gliomas, we investigated the biological effects on the human glioma cell line, U87MG, of antisense olig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a22dcaa3e1dcd8d10e297b5130c93dd
https://pubmed.ncbi.nlm.nih.gov/7476902
https://pubmed.ncbi.nlm.nih.gov/7476902
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 91(22)
Ras oncogenes owe their transforming properties to single point mutations in the sequence coding for the active site of the p21 protein. These mutations lead to changes in cellular proliferation and induce tumorigenic properties. Point mutations repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98deae1c1c7caa45ae3e4de0d563dbca
https://pubmed.ncbi.nlm.nih.gov/7937975
https://pubmed.ncbi.nlm.nih.gov/7937975
Publikováno v:
Pharmaceutical research. 11(9)
Oligonucleotides can be adsorbed on polyisohexylcyanoacrylate nanoparticles in the presence of hydrophobic quarternary ammonium salts. Oligonucleotides bound to nanoparticles are protected from nuclease attack both in buffer and in cell culture media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d9ce608560b2a80b1768354d86f77f1
https://pubmed.ncbi.nlm.nih.gov/7816773
https://pubmed.ncbi.nlm.nih.gov/7816773
Publikováno v:
Biochimie. 75(1-2)
RNase H has been clearly implicated in vitro in mediating some antisense effects. In vivo evidence is limited to experiments performed in Xenopus oocytes in which antisense oligonucleotides are microinjected. In other mammalian cell systems scant dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f86256fc161acd0a8a7cc7828df96a
https://pubmed.ncbi.nlm.nih.gov/8389212
https://pubmed.ncbi.nlm.nih.gov/8389212
Publikováno v:
Pharmaceutical research. 9(4)
Adsorption of oligothymidylates on polyisobutyl- or polyisohexylcyanoacrylate nanoparticles was achieved in the presence of hydrophobic cations such as tetraphenylphosphonium chloride or quaternary ammonium salts. Results suggested that oligonucleoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2aecac1e9c9c5e04382e450cf8dc3e5f
https://pubmed.ncbi.nlm.nih.gov/1495887
https://pubmed.ncbi.nlm.nih.gov/1495887
Publikováno v:
Journal of Clinical Oncology. 22:9736-9736
9736 Background: Evaluation of prostate specific antigen (PSA) is the current screening method for early detection of prostate cancer. PSA is more prostate specific than cancer specific, and elevat...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa0cee6abc76f24110d96109d06b4d2f
https://doi.org/10.1200/jco.2004.22.90140.9736
https://doi.org/10.1200/jco.2004.22.90140.9736
Autor:
Jocelyne Just, K.D. Yamaguchi, Alain Grimfeld, S. R. Schramm, Fatiha Sahraoui, S. Chen, M. Jendoubi, C. Chavany
Publikováno v:
Journal of Allergy and Clinical Immunology. 113:S329
Rationale As proteins are the ultimate effectors of gene expression, we have applied an innovative antibody-based approach to the identification of serum secreted protein markers in pediatric asthma. Methods In this asthmatic population we have analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31f6627fb47da4ba34029b6323cab089
https://doi.org/10.1016/j.jaci.2004.01.692
https://doi.org/10.1016/j.jaci.2004.01.692
Publikováno v:
Bulletin du cancer. 76(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a4b6342d43b6999d2a4f9702b2165b2
https://pubmed.ncbi.nlm.nih.gov/2695179
https://pubmed.ncbi.nlm.nih.gov/2695179