Zobrazeno 1 - 10
of 3 689
pro vyhledávání: '"C, Carroll"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Heme trafficking is essential for cellular function, yet mechanisms of transport and/or heme interaction are not well defined. The System I and System II bacterial cytochrome c biogenesis pathways are developing into model systems for heme t
Externí odkaz:
https://doaj.org/article/def7cd7a4f7d41d4905ef0a02e7b9a10
Autor:
Robert C. Carroll, Simon J. Coles
Publikováno v:
IUCrJ, Vol 11, Iss 4, Pp 578-586 (2024)
Investigation of the analyte soaking conditions on the crystalline sponge {[(ZnI2)3(tpt)2·x(solvent)]n} method using a statistical design of experiments model has provided fundamental insights into the influence of experimental variables. This appro
Externí odkaz:
https://doaj.org/article/737ad0270fac4ab798e35d6c6cbb0ae8
Autor:
Ryuichiro Abe, Nikhil Ram-Mohan, Elizabeth Jordan Zudock, Shawna Lewis, Karen C. Carroll, Samuel Yang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHumoral bactericidal activity was first recognized nearly a century ago. However, the extent of inter-individual heterogeneity and the mechanisms underlying such heterogeneity beyond antibody or complement systems have not been well studied
Externí odkaz:
https://doaj.org/article/27762fa05c714a5994d1b0b26889d634
Autor:
Trevor Jamieson, Kevin Thorpe, Francois Bernier, Melyssa Aronson, Marc Clausen, Rita Kodida, Emma Reble, June C Carroll, Jordan Lerner-Ellis, Yvonne Bombard, Matthew Osmond, Muhammad Mamdani, Ronald Cohn, Emily Seto, Hanna Faghfoury, Josh Silver, Maureen Smith, Lauren Chad, Jan M Friedman, Robin Z Hayeems, Michael Brudno, Gregory Costain, Quynh Pham, Anne-Marie Laberge, Christian Marshall, Cheryl Shuman, Rebekah Jobling, Irfan Dhalla, Serena Shastri-Estrada, Daniel Assamad, Stephanie Luca, Stacy Hewson, Eriskay Liston, Frank Rudzicz, Wendy Ungar, Guylaine D'Amours
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Introduction Genetic testing is used across medical disciplines leading to unprecedented demand for genetic services. This has resulted in excessive waitlists and unsustainable pressure on the standard model of genetic healthcare. Alternative models
Externí odkaz:
https://doaj.org/article/8affa2793f8c4b6b9384324d8a29b5cd
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract PURPOSE Cathepsin B (Cat B) is a cysteine lysosomal protease that is upregulated in many inflammatory diseases and widely expressed in the brain. Here, we used a Cat B activatable near-infrared (NIR) imaging probe to measure glial activation
Externí odkaz:
https://doaj.org/article/359be611fdde4ffda055513fa4260f81
Autor:
Richard G. Bachur, Sheldon L. Kaplan, Cesar A. Arias, Natasha Ballard, Karen C. Carroll, Andrea T. Cruz, Richard Gordon Jr., Salim Halabi, Jeffrey D. Harris, Kristina G. Hulten, Theresa Jacob, Mark D. Kellogg, Adi Klein, Pninit Shaked Mishan, Sergey M. Motov, Octavia M. Peck‐Palmer, Leticia M. Ryan, Ma'anit Shapira, George S. Suits, Henry E. Wang, Alexandra Weissman, Richard E. Rothman
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 5, Iss 3, Pp n/a-n/a (2024)
Abstract Objectives To determine the diagnostic accuracy of a rapid host‐protein test for differentiating bacterial from viral infections in patients who presented to the emergency department (ED) or urgent care center (UCC). Methods This was a pro
Externí odkaz:
https://doaj.org/article/e7fc5ef3cf90420587dd3af3e93259a5
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 5, p e1011869 (2024)
We introduce an innovative, data-driven topological data analysis (TDA) technique for estimating the state spaces of dynamically changing functional human brain networks at rest. Our method utilizes the Wasserstein distance to measure topological dif
Externí odkaz:
https://doaj.org/article/44e816fc9ae9478d88f0dac428b576ab
Autor:
Cecilia Fahlquist-Hagert, Thomas R. Wittenborn, Ewa Terczyńska-Dyla, Kristian Savstrup Kastberg, Emily Yang, Alysa Nicole Rallistan, Quinton Raymond Markett, Gudrun Winther, Sofie Fonager, Lasse F. Voss, Mathias K. Pedersen, Nina van Campen, Alexey Ferapontov, Lisbeth Jensen, Jinrong Huang, John D. Nieland, Cees E. van der Poel, Johan Palmfeldt, Michael C. Carroll, Paul J. Utz, Yonglun Luo, Lin Lin, Søren E. Degn
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Circumstantial evidence suggests that B cells may instruct T cells to break tolerance. Here, to test this hypothesis, we used a murine model in which a single B cell clone precipitates an autoreactive response resembling systemic lupus eryth
Externí odkaz:
https://doaj.org/article/77b3e9364b6c4ef5993ede3e01fc8946
Publikováno v:
IUCrJ, Vol 10, Iss 4, Pp 497-508 (2023)
Utilization of the crystalline sponge {[(ZnI2)3(tpt)2·x(solvent)]n} method has enabled characterization of a novel family of synthetic organic oils. The systematic structural differences and diversity of functional groups offered by 13 related molec
Externí odkaz:
https://doaj.org/article/ba03bbda60d246eab0f40b1b6615717a
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTHeme trafficking is a fundamental biological process, yet its direct study has been hampered due to heme’s tight intracellular regulation, heme cytotoxicity, and the transient nature of trafficking. The bacterial System I and System II cyto
Externí odkaz:
https://doaj.org/article/5f2393c5971e4c4eb9d52935a85a0629