Durability of different initial regimens in HIV-infected patients starting antiretroviral therapy with CD4+ counts <200 cells/mm3 and HIV-RNA >5 log10 copies/mL

Autor: Bruno Cacopardo, M. A. Ursitti, Claudio Maria Mastroianni, Emanuele Nicastri, R. Piolini, A. Antinori, Giustino Parruti, S. Truffa, Ivan Gentile, Giovanni Cassola, E. Girardi, I. Caramma, Andrea Calcagno, Laura Monno, A d'Arminio Monforte, R. Acinapura, Francesca Ceccherini-Silberstein, A. Di Biagio, Gabriella Verucchi, Alessandra Latini, Simone Marcotullio, Nicola Gianotti, C. Balotta, Camilla Tincati, M. C. Moioli, Alessandro Tavelli, Pietro Caramello, Carmen Rita Santoro, C. Abeli, A. Londero, F. Di Martino, R. Iardino, Stefano Bonora, M. Andreoni, A. Costantini, Raffaella Libertone, F. von Schloesser, G. Prota, Annalisa Saracino, Maria Grazia Cecchetto, Antonio Cristaudo, Mauro Zaccarelli, Carmela Pinnetti, Fabrizio Carletti, N. Abrescia, Andrea Giacometti, L. Gallo, Paolo Bonfanti, G. Angarano, E. Quiros Roldan, G. Pellizzer, F. Petrone, Giovanni Mazzarello, Silvia Nozza, R. Orlando, Franco Baldelli, Giovanni Guaraldi, Paola Meraviglia, Laura Sighinolfi, S. Carrara, D. Segala, Giuliano Rizzardini, C. Suardi, P. Piano, Mauro Sciandra, Daniela Francisci, A. De Luca, Patrizia Lorenzini, Paola Cinque, Tiziana Quirino, S. Graziano, Cristina Mussini, Massimo Galli, Giuseppe Ippolito, S. Lo Caputo, Benedetto Maurizio Celesia, C. Valeriani, Matteo Bassetti, Maria Rosaria Capobianchi, Claudio Viscoli, Vinicio Manfrin, Alessandro Chiodera, Alessandra Bandera, Guglielmo Borgia, Cinzia Puzzolante, Stefano Rusconi, Leonardo Calza, Valeria Belvisi, Francesca Vichi, Serena Quartu, Roberto Cauda, J. Vecchiet, Antonio Chirianni, A. Di Caro, P.E. Manconi, Stefania Cicalini, G. Magnani, M. Lichtner, Milensu Shanyinde, Stefano Savinelli, M. Puoti, Giulia Marchetti, Laura Carenzi, Carlo Federico Perno, Annalisa Ridolfo, G. Di Perri, F. Maggiolo, A Castagna, G. Orofino, Roberto Rossotti, Francesco Mazzotta, Gianmaria Baldin, Giovanni Lapadula, A. Rodano, V. Donati, Barbara Rossetti, F. Viviani, Adriana Ammassari, N. Bobbio, Adriano Lazzarin, C. Minardi, A. Alessandrini, Katia Falasca, Maria Stella Mura, Tamara Ursini, Andrea Gori, A. Cingolani, L. Maddaloni, Alessandro Cozzi-Lepri, Francesco Castelli, Iuri Fanti, Giordano Madeddu, E. Quiros, P. Viale, Marco Borderi, M. Capozzi, Vincenzo Vullo

Publikováno v: Journal of Antimicrobial Chemotherapy. 74:2732-2741

ObjectivesOur aim was to investigate the durability of different initial regimens in patients starting ART with CD4+ counts 5 log10 copies/mL.MethodsThis was a retrospective study of HIV-infected patients prospectively followed in the ICONA cohort. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fbb99d54686c78a368f229e5371836
https://doi.org/10.1093/jac/dkz237

Duplex droplet digital PCR to study the composition of HIV-DNA in blood cells

Autor: A. Lai, S. Gioffrè, F.R. Simonetti, P. Cattaneo, C. Balotta

Publikováno v: Journal of Virus Eradication, Vol 1, Iss, Pp 30-(2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4cce229f5024cb54f4e98081c12a11
http://www.sciencedirect.com/science/article/pii/S205566402031373X

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Comparison between HIV- and CMV-specific T cell responses in long-term HIV infected donors

Autor: Sarah Rowland-Jones, T Rostron, Philippa Easterbrook, Annapurna Vyakarnam, Julian Sutton, Abigail S. King, Laura Papagno, C. Balotta, A. T. Makadzanhge, Anele Waters, Graham S. Ogg, Victor Appay, Geraldine M. Gillespie

Publikováno v: Clinical and Experimental Immunology. 130:509-517

Summary The mechanisms underlying non-progression in HIV-1 infection are not well understood; however, this state has been associated previously with strong HIV-1-specific CD8+ T cell responses and the preservation of proliferative CD4+ T cell respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5534df3cac06f022f5ed8430e8922a7e
https://doi.org/10.1046/j.1365-2249.2002.02005.x

Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages

Autor: Paolo Lusso, Richard W. Crowley, Genoveffa Franchini, Robert C. Gallo, C Balotta

Publikováno v: Scopus-Elsevier

The replication of human immunodeficiency viruses (HIV) in human macrophages is influenced by genetic determinants which have been mapped predominantly to the viral envelope. However, in HIV-2, the vpr gene has also been suggested as an important mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015982d13cc9449cbb8970c148e3d0f5
https://doi.org/10.1128/jvi.67.7.4409-4414.1993