Effect on non-vascular outcomes of lowering LDL cholesterol in patients with chronic kidney disease: results from the Study of Heart and Renal Protection

Autor: C. Reith, N. Staplin, W. G. Herrington, W. Stevens, J. Emberson, R. Haynes, M. Mafham, J. Armitage, A. Cass, J. C. Craig, L. Jiang, T. Pedersen, C. Baigent, M. J. Landray, on behalf of the SHARP Collaborative Group

Publikováno v: BMC Nephrology, Vol 18, Iss 1, Pp 1-9 (2017)

Abstract Background Reducing LDL cholesterol (LDL-C) with statin-based therapy reduces the risk of major atherosclerotic events among patients with chronic kidney disease (CKD), with no evidence of an excess risk of cancer or death from any non-vascu

Externí odkaz: https://doaj.org/article/38596814f34b4338b23e3731801e6a2d

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Cost-effectiveness of statin therapy in categories of patients in the UK

Autor: B Mihaylova, R Wu, C Williams, J Zhou, I Schlackow, J Emberson, C Reith, A Keech, J Robson, K Wilkinson, J Armitage, R Collins, A Gray, J Simes, C Baigent

Publikováno v: European Heart Journal. 43

Background Cardiovascular disease (CVD) mortality has declined steadily over the last few decades across Europe and North America. Purpose To provide contemporary estimates of long-term effectiveness and cost-effectiveness of statin therapy in differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6c2ac496d149a2b992aec358fd037ea
https://doi.org/10.1093/eurheartj/ehac544.2841

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Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis

Autor: Milad Nazarzadeh, Zeinab Bidel, Dexter Canoy, Emma Copland, Derrick A Bennett, Abbas Dehghan, George Davey Smith, Rury R Holman, Mark Woodward, Ajay Gupta, Amanda I Adler, Malgorzata Wamil, Naveed Sattar, William C Cushman, Richard J McManus, Koon Teo, Barry R Davis, John Chalmers, Carl J Pepine, Kazem Rahimi, L Agodoa, A Algra, F W Asselbergs, N Beckett, E Berge, H Black, F P J Brouwers, M Brown, C J Bulpitt, B Byington, J Cutler, R B Devereaux, J Dwyer, R Estacio, R Fagard, K Fox, T Fukui, Y Imai, M Ishii, S Julius, Y Kanno, S E Kjeldsen, J Kostis, K Kuramoto, J Lanke, E Lewis, J Lewis, M Lievre, L H Lindholm, S Lueders, S MacMahon, G Mancia, M Matsuzaki, M H Mehlum, S Nissen, H Ogawa, T Ogihara, T Ohkubo, C Palmer, A Patel, M Pfeffer, N R Poulter, H Rakugi, G Reboldi, C Reid, G Remuzzi, P Ruggenenti, T Saruta, J Schrader, R Schrier, P Sever, P Sleight, J A Staessen, H Suzuki, L Thijs, K Ueshima, S Umemoto, W H van Gilst, P Verdecchia, K Wachtell, P Whelton, L Wing, Y Yui, S Yusuf, A Zanchetti, Z Y Zhang, C Anderson, C Baigent, BM Brenner, R Collins, D de Zeeuw, J Lubsen, E Malacco, B Neal, V Perkovic, B Pitt, A Rodgers, P Rothwell, G Salimi-Khorshidi, J Sundström, F Turnbull, G Viberti, J Wang

Publikováno v: Nazarzadeh, M, Bidel, Z, Canoy, D, Copland, E, Bennett, D A, Dehghan, A, Davey Smith, G, Holman, R R, Woodward, M, Gupta, A, Adler, A I, Wamil, M, Sattar, N, Cushman, W C, McManus, R J, Koon, T, Davis, B R, Chalmers, J, Pepine, C J & Rahimi, K 2022, ' Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes : an individual participant-level data meta-analysis ', Lancet Diabetes and Endocrinology, vol. 10, no. 9, pp. 645-654 . https://doi.org/10.1016/S2213-8587(22)00172-3

Background Controversy exists as to whether the threshold for blood pressure-lowering treatment should differ between people with and without type 2 diabetes. We aimed to investigate the effects of blood pressure-lowering treatment on the risk of maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44422d6b20717ea24c63a10d59c54203
https://pubmed.ncbi.nlm.nih.gov/36427521