Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Byunghee Yoo"'
Publikováno v:
Applied Sciences, Vol 14, Iss 2, p 664 (2024)
Leveraging natural language processing models using a large volume of text data in the construction safety domain offers a unique opportunity to improve understanding of safety accidents and the ability to learn from them. However, little effort has
Externí odkaz:
https://doaj.org/article/08707842ca4647d3996e3c18d4a9e6b9
Autor:
N. Anna Savan, Paulo Vilar Saavedra, Alan Halim, Vilma Yuzbasiyan-Gurkan, Ping Wang, Byunghee Yoo, Matti Kiupel, Lorenzo Sempere, Zdravka Medarova, Anna Moore
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Ninety percent of deaths from cancer are caused by metastasis. miRNAs are critical players in biological processes such as proliferation, metastasis, apoptosis, and self-renewal. We and others have previously demonstrated that miRNA-10b promotes meta
Externí odkaz:
https://doaj.org/article/08e05b70878c452684172a1cc0482271
Autor:
Mariane Le Fur, Alana Ross, Pamela Pantazopoulos, Nicholas Rotile, Iris Zhou, Peter Caravan, Zdravka Medarova, Byunghee Yoo
Publikováno v:
Cancer Nanotechnology, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Background In our earlier work, we identified microRNA-10b (miR10b) as a master regulator of the viability of metastatic tumor cells. This knowledge allowed us to design a miR10b-targeted therapeutic consisting of an anti-miR10b antagomir co
Externí odkaz:
https://doaj.org/article/7b7d769c8b584fca8bd0e493831dea3f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract RNA interference represents one of the most appealing therapeutic modalities for cancer because of its potency, versatility, and modularity. Because the mechanism is catalytic and affects the expression of disease-causing antigens at the pos
Externí odkaz:
https://doaj.org/article/aba3c435f7b44d53a08fc458de111e51
Autor:
Byunghee Yoo, Nikhil Meka, Patrick Sheedy, Ann-Marie Billig, Pamela Pantazopoulos, Zdravka Medarova
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226356 (2019)
Prior research has shown that critical differences between non-metastatic and metastatic tumor cells are at the level of microRNA. Consequently, harnessing these molecules for the treatment of metastatic cancer could have significant clinical impact.
Externí odkaz:
https://doaj.org/article/3be13adc8eb04672a9fa28565874935c
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Traditional cancer therapy has relied on a strictly cytotoxic approach that views non-metastatic and metastatic tumor cells as identical in terms of molecular biology and sensitivity to therapeutic intervention. Mounting evidence suggests that, in fa
Externí odkaz:
https://doaj.org/article/1760f97ad86f4017ace7354767905317
Autor:
Byunghee Yoo, Patricia Greninger, Giovanna T Stein, Regina K Egan, Joseph McClanaghan, Anna Moore, Cyril H Benes, Zdravka Medarova
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201046 (2018)
Since microRNAs (miRNAs, miRs) have been implicated in oncogenesis, many of them have been identified as therapeutic targets. Previously we have demonstrated that miRNA-10b acts as a master regulator of the viability of metastatic tumor cells and rep
Externí odkaz:
https://doaj.org/article/7d4e07a6112548db9914389c72aecba7
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Traditionally, cancer therapy has relied on surgery, radiation therapy, and chemotherapy. In recent years, these interventions have become increasingly replaced or complemented by more targeted approaches that are informed by a deeper understanding o
Externí odkaz:
https://doaj.org/article/260073d77b3d46448eac86e2ef1be9bf
Lanthanide-Mediated Dephosphorylation Used for Peptide Cleavage during Solid Phase Peptide Synthesis
Autor:
Byunghee Yoo, Mark D. Pagel
Publikováno v:
Molecules, Vol 18, Iss 4, Pp 3894-3905 (2013)
Lanthanide(III) ions can accelerate the hydrolysis of phosphomonoesters and phosphodiesters in neutral aqueous solution. In this paper, lanthanide-mediated dephosphorylation has been applied in aqueous media as an orthogonal cleavage condition that c
Externí odkaz:
https://doaj.org/article/4db8ae38fee148a79389d1e6b6ec8ed8
Autor:
Zdravka Medarova, Anna Moore, Aseda Tena, Pamela Pantazopoulos, Victoria Petkova, Natalia Barteneva, Kornelia Polyak, Doris P. Tabassum, Ping Wang, Alana Ross, Amol Kavishwar, Byunghee Yoo
Supplementary Fig. S6. Gross anatomical features of mice treated with MN-anti-miR10b and doxorubicin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c2f9350dc0a6713e4b365948c2bd06
https://doi.org/10.1158/0008-5472.22407131.v1
https://doi.org/10.1158/0008-5472.22407131.v1