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Autor:
Dan Bloomfield, Naab M. Al‐Saady, Debra Freedholm, Sara Coulter, Norman E. Lepor, Xiaohui Wang, Nancy Widener, Mark Lovern, Constance Cullen, Byungdoo Alexander Yi, Emilie Simard
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:307-315
Background Factor XI (FXI) inhibition offers the promise of hemostasis-sparing anticoagulation for the prevention and treatment of thromboembolic events. Abelacimab (MAA868) is a novel fully human monoclonal antibody that targets the catalytic domain