Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Byung-Chun Yoo"'
Autor:
Ross Sager, Xu Wang, Kristine Hill, Byung-Chun Yoo, Jeffery Caplan, Alex Nedo, Thu Tran, Malcolm J. Bennett, Jung-Youn Lee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Auxin promotes lateral root emergence from pericycle cells in the root vasculature. Here the authors show that induction of the plasmodesmal regulator PDLP5 during lateral root emergence restricts the spatial scope of auxin signaling to the cells ove
Externí odkaz:
https://doaj.org/article/49adbad04b3948e1a53de04a13f9ce2e
Publikováno v:
PeerJ, Vol 8, p e8362 (2020)
We present a new approach to edit both mitochondrial and chloroplast genomes. Organelles have been considered off-limits to CRISPR due to their impermeability to most RNA and DNA. This has prevented applications of Cas9/gRNA-mediated genome editing i
Externí odkaz:
https://doaj.org/article/38e954cafe404bd3b361e7c84f472e24
Publikováno v:
Human Gene Therapy. 34:314-324
Figure S1. Fluorescence compensation of mock transfected, GFP- and ATTO 550-fluorescing cells. Figure S2. Representative images used for time course analysis. Figure S3. In vitro cleavage reaction of wildtype and R34G-mutated NRF2 amplicons with vary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b3da7d77a5cb7115e48adbf58b0236
https://doi.org/10.1158/1541-7786.22513666.v1
https://doi.org/10.1158/1541-7786.22513666.v1
Publikováno v:
Journal of the Korean institute of rural architecture. 23:9-18
Autor:
Kevin Bloh, Zugui Zhang, Eric B. Kmiec, Pawel Bialk, Rohan Kanchana, Kelly Banas, Byung-Chun Yoo
Publikováno v:
The CRISPR Journal
During CRISPR-directed gene editing, multiple gene repair mechanisms interact to produce a wide and largely unpredictable variety of sequence changes across an edited population of cells. Shortcomings inherent to previously available proposal-based i
Publikováno v:
Mol Cancer Res
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)–directed gene editing is approaching clinical implementation in cancer. Thus, it is imperative to define the molecular framework upon which safe and efficacious therapeutic strategi
Autor:
Xu Wang, Kristine Hill, Malcolm J. Bennett, Byung Chun Yoo, Ross Sager, Thu M. Tran, Jeffery L. Caplan, Alex Nedo, Jung-Youn Lee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications
Lateral roots originate from initial cells deep within the main root and must emerge through several overlying layers. Lateral root emergence requires the outgrowth of the new primordium (LRP) to coincide with the timely separation of overlying root
Autor:
Kelly Banas, Shirin Modarai, Natalia Rivera-Torres, Byung-Chun Yoo, Pawel A. Bialk, Connor Barrett, Mona Batish, Eric B. Kmiec
Publikováno v:
Gene therapy. 29(6)
We have been developing CRISPR-directed gene editing as an augmentative therapy for the treatment of non-small cell lung carcinoma (NSCLC) by genetic disruption of Nuclear Factor Erythroid 2-Related Factor 2 (NRF2). NRF2 promotes tumor cell survival
Recent data suggest that a time lag exists between nuclear penetration and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-directed gene editing activity in human cells. As CRISPR/Cas approaches clinical implementation, it is criti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d32a02f0323c9613e40ab3c426212c
https://doi.org/10.1101/799676
https://doi.org/10.1101/799676